Angina, Unstable clinical trials
The registry lists 328 studies for Angina, Unstable across more than 10 countries. 42 are recruiting or about to start. 87 of them are mainly about Angina, Unstable (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-05. Counting its narrower condition Angina Pectoris, Variant too: 360 studies, 51 open.
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Who runs them
University College, London (12) · Collegium Medicum w Bydgoszczy (6) · Massachusetts General Hospital (6) · Seoul National University Hospital (5) · Assistance Publique - Hôpitaux de Paris (4) · Foundation of Cardiovascular Research and Education Enschede (4) · Jun Li (4) · Karolinska Institutet (3)
What is being tested here
Drugs under test in Angina, Unstable studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Colchicine | 2 | 1 | 2 |
| Ticagrelor | 1 | 3 | 11 |
| Aspirin | 1 | 2 | 3 |
| Bempedoic acid | 1 | 0 | 1 |
| Clopidogrel | 0 | 2 | 6 |
| Rivaroxaban | 0 | 1 | 5 |
| Atorvastatin | 0 | 0 | 5 |
| Abciximab | 0 | 2 | 3 |
| Enoxaparin | 0 | 2 | 3 |
| Argatroban | 0 | 0 | 2 |
Drug classes tested here P2Y12 inhibitors 1 open · Factor Xa inhibitors 7 · Statins 7
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Sep 2027Evaluation of Low Dose Colchicine and Ticagrelor in Prevention of Ischemic Stroke in Patients With Stroke Due to Atherosclerosis · Phase 3 · Assistance Publique - Hôpitaux de Paris
- Dec 2026Fractional Flow Reserve Guided Immediate Versus Staged Complete Myocardial Revascularization in Patients With ST-segment Elevation Myocardial Infarction With Multivessel Disease (Future Study) · RenJi Hospital
- Dec 2026A Cohort of Patients Undergoing Percutaneous Coronary Intervention · Su Guohai
- Dec 2026International Survey of Acute Coronary Syndromes · University of Bologna
- Dec 2026SIROOP Registry - a Prospective Registry Study to Evaluate the Outcomes of Coronary Artery Disease Patients Treated with SIROlimus or Paclitaxel Eluting Balloon Catheters · Luzerner Kantonsspital
- Feb 2027Treatment of ACuTe Coronary Syndromes With Low-dose colchICine · Beijing Anzhen Hospital
- Mar 2027Clinical Characteristics, Frailty, and Prognostic Predictors in Patients Aged 75 and Older With Acute Coronary Syndrome · Clinical Center Niš
- May 2027Aerobic Exercise-induced Effect on Endothelial Function in Patients With Ischaemic Heart Disease · Instituto de Investigación Sanitaria y Biomédica de Alicante
- May 2027Japanese Coronary Intervention Using Drug Eluting and Perfusion Therapy for Left Main Disease (JDEPTH-LM Registry) · TCROSS Co., Ltd.
- Jun 2027Advanced NanoTherapies Dual-API DCB to Treat De-Novo and ISR Lesions in Patients With Symptomatic Coronary Artery Disease · Advanced NanoTherapies
Who these studies take
Of the 34 Angina, Unstable studies recruiting now, 29 (85%) set no upper age limit and 3 (9%) stop at 75 or younger. 3 (9%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 3 (9%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (9%) | 3 (9%) |
| 18 | 27 (79%) | 27 (79%) |
| 30 | 32 (94%) | 32 (94%) |
| 40 | 32 (94%) | 32 (94%) |
| 50 | 33 (97%) | 33 (97%) |
| 65 | 33 (97%) | 33 (97%) |
| 75 | 34 (100%) | 34 (100%) |
| 85 | 31 (91%) | 31 (91%) |
Across all 328 studies, recruiting or not: 13% stop at 75 or younger and 2% at 65; 6% take children; 1% are for women only and <1% for men only; 8% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Angina, Unstable studies take
Of 17 phase 4 interventional studies under Angina, Unstable, half reached primary completion within 44 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 4 | 44 mo26–51 · 17 studies | — | — |
| Interventional, no phase | 19 mo13–44 · 50 studies | — | 19 mo12–47 · 42 studies |
| Observational | 38 mo19–71 · 62 studies | — | 47 mo19–86 · 51 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting1
- Early Single Antiplatelet Therapy After IVUS-Guided PCI in Acute Coronary SyndromeNov 5, 2026NCT07684742
Studies
Recruiting first, then most recently updated. Showing 50 of 328. Browse all 328 → or search them.
- Early Single Antiplatelet Therapy After IVUS-Guided PCI in Acute Coronary SyndromeRecruitingNCT07684742Phase 41 country
- Analysis of Life-threatening ARrhythMias After Acute Coronary SyndromeRecruitingNCT078240501 country
- Gangwon PCI Prospective RegistryRecruitingNCT020381271 country
- Early Triple Lipid-Lowering Therapy With Bempedoic Acid After Acute Coronary SyndromeRecruitingNCT07824323Phase 41 country
- Rapid or Ultra-rapid Diagnosis of Myocardial Infarction Using High-Sensitivity Cardiac Troponin on Hospital PresentationNot yet recruitingNCT07727135Not applicable1 country
- Diagnostic Performance of Artificial Intelligence Algorithms in Prediction of Acute Coronary Syndrome Based on White Blood Cell PropertiesRecruitingNCT063848461 country
- Oregano and Basil Leaves and Coronary Artery DiseaseRecruitingNCT07123181Not applicable1 country
- Clinical Characteristics, Frailty, and Prognostic Predictors in Patients Aged 75 and Older With Acute Coronary SyndromeRecruitingNCT073666841 country
- The International Survey of Acute Coronary Syndromes-ARCHIVESEnrolling by invitationNCT040081731 country
- Vascular Senescence and Atherosclerotic Plaque VulnerabilityRecruitingNCT063136451 country
- Prospective Lifespan Cohort of Myocardial InfarctionNot yet recruitingNCT074717631 country
- Safety and Effectiveness of the Crystalline Sirolimus-Eluting Device in Patients With Coronary Artery DiseaseRecruitingNCT074449571 country
- Aerobic Exercise-induced Effect on Endothelial Function in Patients With Ischaemic Heart DiseaseRecruitingNCT06788275Not applicable1 country
- Advanced NanoTherapies Dual-API DCB to Treat De-Novo and ISR Lesions in Patients With Symptomatic Coronary Artery DiseaseRecruitingNCT07368933Not applicable1 country
- Multicenter Study on Cardiovascular and Metabolic Complications in Patients With Biochemically Silent Pheochromocytomas and ParagangliomasEnrolling by invitationNCT073160751 country
- Breaking Fasts Ahead of Cardiac CathsRecruitingNCT06996639Not applicable1 country
- The Influence of Modifying Highly Calcified Coronary Lesions on Coronary MicrocirculationEnrolling by invitationNCT06507449Not applicable1 country
- FAPO-2: Cardiac Patient Monitoring Tool for Clinical Observation and Arrhythmia DetectionRecruitingNCT07174206Not applicable1 country
- Evaluation of Low Dose Colchicine and Ticagrelor in Prevention of Ischemic Stroke in Patients With Stroke Due to AtherosclerosisRecruitingNCT05476991Phase 31 country
- Occurrence of Severe Cardiac Rhythm and Conduction Disturbances in Emergency Department Patients With Non-ST Elevation Acute Coronary SyndromeNot yet recruitingNCT071125471 country
- LEADERS FREE IV (RCT): BioFreedom™ Ultra vs BioFreedom™ in HBR PatientsRecruitingNCT06657326Not applicable1 country
- A Multi-center, Real-World Clinical Trial of caIMR on Two Specific Kinds of Patients.Not yet recruitingNCT06945094
- Scientific Rationale and Design for a Prospective Study to Codify Coronary Lesions Based on Fluid Mechanics and Acoustic MechanismsNot yet recruitingNCT06868225
- International Survey of Acute Coronary SyndromesRecruitingNCT012187761 country
- Japanese Coronary Intervention Using Drug Eluting and Perfusion Therapy for Left Main Disease (JDEPTH-LM Registry)RecruitingNCT064360921 country
- Coronary Computed Tomography Versus Invasive Angiography for Non-ST Elevation Acute Coronary SyndromeRecruitingNCT06101862Not applicable1 country
- Treatment of ACuTe Coronary Syndromes With Low-dose colchICineRecruitingNCT06215989Not applicable1 country
- COMPLEX Registry - a Prospective COhort Study to Describe the Management and Outcomes of Patients Presenting with CompLEX and Calcified Coronary Artery DiseaseRecruitingNCT060756021 country
- SIROOP Registry - a Prospective Registry Study to Evaluate the Outcomes of Coronary Artery Disease Patients Treated with SIROlimus or Paclitaxel Eluting Balloon CathetersRecruitingNCT049886851 country
- Body Composition Estimated by Bioelectrical Impedance Analysis in Patients with Acute Coronary Syndrome.RecruitingNCT065618151 country
- Management Tactics for Patients High Risk With Acute Coronary Syndrome Without ST Segment Elevation and Multivessel Coronary Artery DiseaseRecruitingNCT06279663Not applicable1 country
- Identification of Biomarkers in Subjects With Coronary Syndrome (PLAQUE Study)RecruitingNCT061033571 country
- Implementation of Contemporary Coronary CT Angiography in Clinical PracticeRecruitingNCT062730331 country
- Distal Radial Access for Coronary ProceduresRecruitingNCT061654061 country
- Fractional Flow Reserve Guided Immediate Versus Staged Complete Myocardial Revascularization in Patients With ST-segment Elevation Myocardial Infarction With Multivessel Disease (Future Study)RecruitingNCT05967663Not applicable1 country
- Therapeutic Use of Contrast Ultrasound in Acute Coronary Artery DiseaseRecruitingNCT047320912 countries
- RNA as Prognostic Biomarkers in Patients With Acute Coronary SyndromeRecruitingNCT060581821 country
- Post-Revascularization Optimization and PHysiological Evaluation of intermediaTe LesionsRecruitingNCT050566621 country
- The Flash FFR Ⅱ StudyRecruitingNCT04575207Not applicable1 country
- A Cohort of Patients Undergoing Percutaneous Coronary InterventionRecruitingNCT057195451 country
- PRospective Evaluation of Complete Revascularization in Patients With multiveSsel Disease Excluding chroNic Total OcclusionsRecruitingNCT05230446Not applicable1 country
- Unstable Angina Pectoris in Comorbidity With Anxiety-depressive SyndromeRecruitingNCT045996211 country
- Intracoronary Cryotherapy Effect on Stabilization of Vulnerable Plaque in Patients With (N)STEMI or Unstable AnginaCompletedNCT05600088Not applicable2 countries
- Prediction of Adverse Events From Non-PCI Coronary Plaques Using Machine LearningCompletedNCT078661441 country
- Emergency Department Triage of Patients With Acute Chest Pain Based on the ESC 0/1-hour Algorithm (PRESC1SE-MI)Active, not recruitingNCT05649384Not applicable11 countries
- A Study Assessing Repatha® in Combination With Standard of Care (SOC) Compared With SOC on Major Cardiovascular Events in Chinese Participants With Atherosclerotic Cardiovascular DiseaseActive, not recruitingNCT062956791 country
- A Study of Population and Sex-specific Troponin Cutoffs for Ruling Out Acute Myocardial InfarctionCompletedNCT05336435Not applicable1 country
- A MAajor RAdiation-based PCI Study in STEMI and NSTEMIActive, not recruitingNCT065657931 country
- European Survey of Cardiovascular Disease Prevention, Diabetes and Chronic Kidney Disease (EUROASPIRE VI)Active, not recruitingNCT064951771 country
- Validation of the MedHub AutocathFFR Software Device for Non-Invasive Fractional Flow Reserve (FFR)CompletedNCT077637691 country