Microvascular Angina clinical trials
The registry lists 111 studies for Microvascular Angina across more than 10 countries. 39 are recruiting or about to start. 71 of them are mainly about Microvascular Angina (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
Qilu Hospital of Shandong University (6) · University Hospital, Grenoble (4) · NHS National Waiting Times Centre Board (4) · Bispebjerg Hospital (3) · Samsung Medical Center (3) · Johannes Gutenberg University Mainz (2) · National Heart, Lung, and Blood Institute (NHLBI) (2) · Queen Mary University of London (2)
What is being tested here
Drugs under test in Microvascular Angina studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Nebivolol | 1 | 1 | 2 |
| Cisplatin | 1 | 0 | 1 |
| Bexagliflozin | 1 | 0 | 1 |
| Amlodipine | 1 | 1 | 1 |
| Diltiazem | 0 | 1 | 2 |
| Ranolazine | 0 | 0 | 2 |
| Bivalirudin | 0 | 0 | 1 |
| Adenosine | 0 | 0 | 1 |
| Heparin | 0 | 0 | 1 |
| Prednisolone | 0 | 1 | 1 |
Drug classes tested here Calcium channel blockers 1 open · Beta blockers 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026Efficacy of Targeted Medical Therapy in Angina and Nonobstructive Coronary Arteries · Phase 3 · Stanford University
- Dec 2026Self-Expanding Coronary Sinus Reducer for Treatment of Symptomatic Coronary Microvascular Dysfunction (CMD) (SERRA-I Study) · VahatiCor, Inc.
- Dec 2026The FLARE (Flurpiridaz vs. Rubidium Evaluation) Trial · University of California, Los Angeles
- Dec 2026Non-invasive Diagnosis of Coronary Microvascular Disease: Pilot Study · University of Leicester
- Dec 2026Relationship Between Coronary Microvascular Dysfunction and Improvement of Left Ventricular Systolic Function in Patients With Heart Failure With Reduced Ejection Fraction Caused by Non-ischemic Etiology · Samsung Medical Center
- Dec 2026Compound Danshen Dripping Pill for Diabetic Microvascular Angina · Qilu Hospital of Shandong University
- Jan 2027Comprehensive Coronary Physiology in Patients With Angina With Nonobstructive Coronary Arteries - Czech Republic · University Hospital, Motol
- Apr 2027Microvascular Coronary Rehabilitation For Improving Treatment - Feasibility Study · Royal United Hospitals Bath NHS Foundation Trust
- Jun 2027Microvascular Angina Intervention With Compound Danshen Dripping Pill (MAIDS) · Qilu Hospital of Shandong University
- Jul 2027Serial PET MPI in Patients Undergoing Cancer Treatment · University of California, Los Angeles
Who these studies take
Of the 27 Microvascular Angina studies recruiting now, 18 (67%) set no upper age limit and 3 (11%) stop at 75 or younger. 1 (4%) take children under 18. 1 (4%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 21 (78%) | 20 (74%) |
| 30 | 24 (89%) | 23 (85%) |
| 40 | 26 (96%) | 25 (93%) |
| 50 | 27 (100%) | 26 (96%) |
| 65 | 27 (100%) | 26 (96%) |
| 75 | 27 (100%) | 26 (96%) |
| 85 | 22 (81%) | 21 (78%) |
Across all 111 studies, recruiting or not: 15% stop at 75 or younger and 4% at 65; 5% take children; 7% are for women only and 0% for men only; 13% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Microvascular Angina studies take
Of 24 interventional studies with no phase under Microvascular Angina, half reached primary completion within 39 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 39 mo24–64 · 24 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered1
- Coronary MicrovAscular Diseases Intervention With Compound Danshen Dropping PillsOct 21, 2026NCT07885462
Studies
Recruiting first, then most recently updated. Showing 50 of 111. Browse all 111 → or search them.
- Evaluation of the Systemic Microcirculation as a Surrogate for Coronary Microcirculation in Women With ANOCANot yet recruitingNCT07558018
- Simultaneous Measurement of EpicArdial and Microvascular ResisTance Via Angiographic FLOW StudyEnrolling by invitationNCT076760972 countries
- The Value of Measuring Retinal Vascular Density by Optical Coherence Tomography-Angiography (OCT-A) in Patients With Microvascular Angina Confirmed by Myocardial Microcirculatory Resistance Index (MRI).RecruitingNCT066927511 country
- Coronary MicrovAscular Diseases Intervention With Compound Danshen Dropping PillsNot yet recruitingNCT07885462Phase 41 country
- Study Targeting Myocardial Perfusion and Symptom Relief in Women With SGLT2 Inhibitors (STRONG)RecruitingNCT06600178Phase 11 country
- A Study of Microcirculatory Function in Type 2 Myocardial Infarction (T2MI)Not yet recruitingNCT057935671 country
- The FLARE (Flurpiridaz vs. Rubidium Evaluation) TrialEnrolling by invitationNCT077617281 country
- Microvascular Coronary Rehabilitation For Improving Treatment - Feasibility StudyRecruitingNCT06681896Not applicable1 country
- Non-invasive Diagnosis of Coronary Microvascular Disease: Pilot StudyRecruitingNCT060706621 country
- iCorMicA - Stratified Medicine in AnginaRecruitingNCT04674449Not applicable4 countries
- Coronary Flow During Rapid Heart RatesRecruitingNCT058411991 country
- Coronary Sinus Reducer in Coronary Microvascular DiseaseEnrolling by invitationNCT06898541Not applicable1 country
- Barts-MINOCA RegistryRecruitingNCT044407611 country
- POLish Registry of CArdioneuroablation and CArdioneuromodulationRecruitingNCT071963971 country
- An Observational Study of Coronary Microvascular Disease of ChinaRecruitingNCT066761371 country
- A Clinical Study of Fundus OCTA for the Identification of CMDRecruitingNCT057431401 country
- Serial PET MPI in Patients Undergoing Cancer TreatmentEnrolling by invitationNCT059139991 country
- Comprehensive Coronary Physiology in Patients With Angina With Nonobstructive Coronary Arteries - Czech RepublicRecruitingNCT071033171 country
- Comparative Study of Magnetocardiography and Emission Computed Tomography.Not yet recruitingNCT07078266
- Clinical Evaluation of Aromatic Wentong in the Treatment of Coronary Microvascular DiseaseNot yet recruitingNCT06901570Phase 41 country
- Sex Difference of Coronary Microvascular Dysfunction in Patients With Non-obstructive Coronary Artery DiseaseRecruitingNCT060765511 country
- Angina After PCI: a Systems Medicine StudyEnrolling by invitationNCT068543021 country
- Impact of Exercise Training on Ischemia With Non-Obstructive Coronary Arteries (INOCA): The ExINOCA StudyRecruitingNCT06529848Not applicable1 country
- Evaluation of the Efficacy of MACitentan in the Treatment of CoronaryMICrovascular Angina (MACMIC)RecruitingNCT06811831Early Phase 11 country
- Nebivolol ANOCA Treatment Randomized TrialNot yet recruitingNCT06755801Phase 3
- Compound Danshen Dripping Pill for Diabetic Microvascular AnginaNot yet recruitingNCT06727890Phase 41 country
- Efficacy of Targeted Medical Therapy in Angina and Nonobstructive Coronary ArteriesRecruitingNCT06424834Phase 2/31 country
- Qishenyiqi Dripping Pill for Coronary Microvascular DiseaseRecruitingNCT06699420Phase 41 country
- Multicenter Registry on Microvascular Dysfunction - Searching a New Ach Spasm DefinitionRecruitingNCT061253921 country
- Artificial Intelligence With DEep Learning on COROnary Microvascular DiseaseRecruitingNCT045989971 country
- Personalized Medicine Using Coronary Microvascular Function Measured in Patient With Percutaneous Coronary Intervention in AnginaRecruitingNCT05178914Not applicable1 country
- Southeastern Europe Microcirculation RegistryRecruitingNCT063934785 countries
- Transcutaneous Electrical Nerve Stimulation in Patients With Angina and Non-Obstructive Coronary ArteriesRecruitingNCT06401291Not applicable1 country
- Relationship Between Coronary Microvascular Dysfunction and Improvement of Left Ventricular Systolic Function in Patients With Heart Failure With Reduced Ejection Fraction Caused by Non-ischemic EtiologyRecruitingNCT062436531 country
- Clinical Trial for Evaluating the Effectiveness and Safety of Online caIMR in STEMI PatientsRecruitingNCT061184501 country
- Microvascular Angina Intervention With Compound Danshen Dripping Pill (MAIDS)RecruitingNCT06092736Phase 41 country
- COSIMA: COronary SInus Reducer for the Treatment of Refractory Microvascular AnginaRecruitingNCT04606459Not applicable1 country
- Abnormal Coronary Vasomotion in Patients With Suspected Coronary Artery Disease (CAD)RecruitingNCT00921856Not applicable1 country
- Coronary Artery Disease and Coronary Microvascular Disease in Cardiomyopathies RegistryRecruitingNCT034795801 country
- A Single Center Diagnostic, Cross-sectional Study of Coronary Microvascular DysfunctionActive, not recruitingNCT03537586Not applicable1 country
- Insulin Resistance and Coronary Microvascular Dysfunction in Patients With Myocardial Ischemia and Non-obstructive Coronary Artery DiseaseActive, not recruitingNCT06597851Not applicable1 country
- The DISCOVER INOCA Prospective Multi-center RegistryActive, not recruitingNCT052883611 country
- Self Expanding Coronary Sinus Reducer for Treatment of Symptomatic Coronary Microvascular Dysfunction (CMD)SuspendedNCT07449325Not applicable1 country
- Self-Expanding Coronary Sinus Reducer for Treatment of Symptomatic Coronary Microvascular Dysfunction (CMD) (SERRA-I Study)Active, not recruitingNCT06991322Not applicable3 countries
- Coronary Sinus Reducer Implantation in Patients With Ischaemia and Non-obstructed Coronary Arteries and Coronary Microvascular Dysfunction.Active, not recruitingNCT05492110Not applicable1 country
- Endothelin Role In COronary MicrocirculationActive, not recruitingNCT07670091Not applicable1 country
- A Placebo-Controlled Trial of CLBS16 in Subjects With Coronary Microvascular DysfunctionTerminatedNCT04614467Phase 21 country
- Standardizing the Management of Patients With Coronary Microvascular DysfunctionActive, not recruitingNCT06025994Not applicable1 country
- Multicenter Registry of Coronary Flow-Derived Indexes for Coronary Microvascular Disease (Multicenter FLOW-CMD Registry)Active, not recruitingNCT053691821 country
- Exercise and Coronary Microvascular DiseaseActive, not recruitingNCT05810051Not applicable1 country