Amputation, Traumatic clinical trials
The registry lists 112 studies for Amputation, Traumatic across more than 10 countries. 24 are recruiting or about to start. 94 of them are mainly about Amputation, Traumatic (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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Who runs them
Gaziler Physical Medicine and Rehabilitation Education and Research Hospital (8) · Shirley Ryan AbilityLab (8) · Point Designs (6) · University of Michigan (4) · US Department of Veterans Affairs (4) · VA Office of Research and Development (3) · Hacettepe University (3) · Centre hospitalier de l'Université de Montréal (CHUM) (3)
What is being tested here
Drugs under test in Amputation, Traumatic studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Antibodies, Monoclonal | 1 | 1 | 1 |
| Tacrolimus | 1 | 1 | 1 |
| Amitriptyline | 0 | 0 | 1 |
| Methadone | 0 | 0 | 1 |
| Interleukin-2 | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 6
- Nov 2026Anaesthetic Technique for Minor Lower Limb Amputation Surgery (ATLLAS) · University Hospitals of North Midlands NHS Trust
- Dec 2026Clinical and Functional Assessment of Patients With Transfemoral Amputation Treated With Osteointegrated Implant · Istituto Ortopedico Rizzoli
- Dec 2026Feasibility of Using an App for Managing Phantom Limb Pain Associated with Combat Injury in Ukraine (PAMELA) · Winfried Meißner
- Mar 2027Prospective Study on the Role of Intravenous Unfractionated Heparin Following Digital Replantation and Revascularization · Centre hospitalier de l'Université de Montréal (CHUM)
- Apr 2027To Evaluate the Clinical Impact of the Point Powered System · Point Designs
- Jun 2027Improving Mobility and Function Following Transfemoral Amputation: A Novel Approach to Reverse Volumetric Muscle Loss · University of Illinois at Chicago
Who these studies take
Of the 18 Amputation, Traumatic studies recruiting now, 6 (33%) set no upper age limit and 9 (50%) stop at 75 or younger. 1 (6%) take children under 18. 0 (0%) are for women only and 3 (17%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 13 (72%) | 16 (89%) |
| 30 | 15 (83%) | 18 (100%) |
| 40 | 15 (83%) | 18 (100%) |
| 50 | 15 (83%) | 18 (100%) |
| 65 | 14 (78%) | 16 (89%) |
| 75 | 9 (50%) | 9 (50%) |
| 85 | 9 (50%) | 9 (50%) |
Across all 112 studies, recruiting or not: 50% stop at 75 or younger and 32% at 65; 5% take children; 0% are for women only and 7% for men only; 21% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Amputation, Traumatic studies take
Of 46 interventional studies with no phase under Amputation, Traumatic, half reached primary completion within 27 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 27 mo14–51 · 46 studies | — | 31 mo13–58 · 38 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 112. Browse all 112 → or search them.
- Clinical and Functional Assessment of Patients With Transfemoral Amputation Treated With Osteointegrated ImplantRecruitingNCT06737770Not applicable1 country
- Cryo NerVe Block Extremity AmputatioN RegIStry for Post Operative and pHantom Limb PainRecruitingNCT069085381 country
- Transtibial OsseointegrationRecruitingNCT06636136Not applicable1 country
- REsistance and LOADing Exercise for Bone HealthRecruitingNCT07817381Not applicable1 country
- Dual-Task Balance Training in Traumatic Lower-Limb Prosthesis UsersRecruitingNCT07706452Not applicable1 country
- Human Penile AllotransplantationRecruitingNCT02395497Phase 2/31 country
- To Evaluate the Clinical Impact of the Point Powered SystemNot yet recruitingNCT07135947Not applicable1 country
- Post-Amputation Stump Infection as a Predictor of Persistent Residual Limb Pain: A Prospective Cohort StudyNot yet recruitingNCT07438795
- Human Upper Extremity AllotransplantationRecruitingNCT01459107Phase 21 country
- Human Upper Extremity Allotransplantation: F/U ProtocolRecruitingNCT034003451 country
- Prospective Study on the Role of Intravenous Unfractionated Heparin Following Digital Replantation and RevascularizationRecruitingNCT04725201Phase 41 country
- DExterous Hand Control Through Fascicular Targeting (DEFT) - (Human Subjects)RecruitingNCT02994160Not applicable1 country
- Evaluation of Myoelectric Implantable Recording Array (MIRA) in Participants With Transradial AmputationRecruitingNCT05768802Not applicable1 country
- Anaesthetic Technique for Minor Lower Limb Amputation Surgery (ATLLAS)Not yet recruitingNCT072446271 country
- Operative Treatment vs Treatment With Semi-occlusive Dressing for Single Finger AmputationsRecruitingNCT07175675Not applicable1 country
- Improving Mobility and Function Following Transfemoral Amputation: A Novel Approach to Reverse Volumetric Muscle LossRecruitingNCT05929508Not applicable1 country
- Comparison Between Digital Nerve Microanastomosis and Traction Neurectomy in Post-Digital Amputation PainNot yet recruitingNCT07102654
- Effects of Myoelectric Channel Count and Targeting for Upper Limb Prosthetic ControlRecruitingNCT07011420Not applicable1 country
- Neuromusculoskeletal Interface for Bionic ArmsNot yet recruitingNCT07032753Not applicable1 country
- Feasibility of Using an App for Managing Phantom Limb Pain Associated with Combat Injury in Ukraine (PAMELA)Not yet recruitingNCT066045071 country
- Understanding How Powered Componentry Impacts K2-Level Transfemoral Amputee GaitRecruitingNCT06433648Not applicable1 country
- Medical Economic Evaluation of Bilateral Allograft of Hands and ForearmsRecruitingNCT02797457Not applicable1 country
- Evaluation of Functionality of Amputees According to the Medicare Functional K Classification SystemRecruitingNCT06293443Not applicable1 country
- The Relationship Between Thicknesses and Isokinetic Strength of Hip Flexor and Extensor MusclesRecruitingNCT058277441 country
- SoftHand Comparison StudyCompletedNCT05328934Not applicable1 country
- Early Discovery of Ischemia After Replantation Surgery of the ExtremitiesActive, not recruitingNCT05297266Not applicable1 country
- Cryoanalgesia to Treat Phantom Limb Pain Following Above-Knee AmputationCompletedNCT06071715Not applicable1 country
- Assessing the Usability and Reliability of the Prototype Prosthesis DevicesCompletedNCT06616402Not applicable1 country
- Criteria for Advanced Prosthetic Foot PrescriptionActive, not recruitingNCT03505983Not applicable1 country
- A Comparative Assessment of Transfemoral Prosthetic SocketsCompletedNCT04038580Not applicable1 country
- Optimizing Rehabilitation for Phantom Limb Pain Using Mirror Therapy and Transcranial Direct Current Stimulation (tDCS)Active, not recruitingNCT02487966Not applicable2 countries
- Study to Identify the Genetic Variations Associated With Phantom Limb PainCompletedNCT014624481 country
- Functional Importance of a Powered Multifunction Wrist ProtocolCompletedNCT04069793Not applicable1 country
- Low Cost Socket for Lower Limb AmputeesCompletedNCT04725461Not applicable1 country
- GaMA Metric to Quantify Functional Importance of Various Upper Limb Prosthetic DevicesActive, not recruitingNCT06420687Not applicable1 country
- To Assess the Utility of the Point Partial in a Clinical Take-home Study of Partial Hand AmputeesCompletedNCT05012683Not applicable1 country
- Dexterous Partial Hand Prosthesis OutcomesCompletedNCT05038566Not applicable1 country
- Teleoperation Experimental Comparison With Able-bodied SubjectsCompletedNCT05048394Not applicable1 country
- Functional Electrical Stimulation Use in Trans-tibial AmputationsCompletedNCT02931396Not applicable1 country
- Evaluation of Dexterous Terminal DeviceWithdrawnNCT05840601Not applicable
- Validation of Point Partial User Needs With Partial Finger AmputeesCompletedNCT05012657Not applicable1 country
- Tap Dance for Adults With Lower Limb AmputationCompletedNCT06334146Not applicable1 country
- Validation of User Needs of the Point Digit With Partial Hand AmputeesCompletedNCT04763278Not applicable1 country
- Study on the Functionality, Safety and Reliability of a Robotic Prosthesis for the Lower Limb At the Transfemoral LevelCompletedNCT06284005Not applicable1 country
- Whole-body Vibration Without Visual Feedback on Postural Steadiness in Unilateral Trans-femoral Traumatic AmputeesCompletedNCT06284733Not applicable1 country
- Studying Electromyographic Activity in Patients With Upper Limb AmputationsCompletedNCT02956603Not applicable
- Sagittal Spinopelvic Parameters in Patients With Lower Extremity AmputationCompletedNCT053185081 country
- No Power Bionic Lower Extremity ProsthesisCompletedNCT04070105Not applicable1 country
- Comparison of Classical Prosthesis and Silicone ProsthesisCompletedNCT058501041 country
- To Assess the Utility of the Point Digit in a Clinical Take-home StudyCompletedNCT04755790Not applicable1 country