VA Office of Research and Development: Frailty trials

The registry lists 11 Frailty studies with VA Office of Research and Development as lead sponsor. 2 are open to participants now and 5 have results posted.

Phase 1 1Phase 2 1Phase 3 1No phase 9(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Partnered Evaluation to Improve the Identification and Management of Functional Impairment and Frailty Among Older Veterans in Primary Care SettingsRecruitingNCT06404970Not applicable
• High Intensity Interval Training (HIIT) to Reduce Frailty and Enhance Resilience in Older VeteransRecruitingNCT05625204Not applicable
• Prehabilitation of Veterans With Exercise and NutritionCompletedNCT04485611Not applicableResults posted
• Diet and Exercise Plus Metformin to Treat Frailty in Obese SeniorsCompletedNCT04221750Phase 3Results posted
• Enhancing Functional Capacity in Older Adults With Short Session High Intensity Interval TrainingTerminatedNCT03750006Not applicableResults posted
• Pilot Testing a Home-Based Rehabilitation Intervention Designed to Improve Outcomes of Frail Veterans Following Cardiothoracic SurgeryCompletedNCT03299101Not applicableResults posted
• Piloting Prehabilitation Before Abdominal SurgeryCompletedNCT03040336Not applicableResults posted
• Promoting Cognitive Resilience and Reducing Frailty in Older Veterans With Bright Light TherapyActive, not recruitingNCT05631236Not applicable
• Mesenchymal Stem Cells for Age-Related FrailtyWithdrawnNCT05284604Phase 1/2
• PAtient-centered mUltidiSciplinary Care for vEterans Undergoing Surgery (PAUSE)Active, not recruitingNCT05037292Not applicable
• Impacts of Nicotinamide Riboside on Functional Capacity and Muscle Physiology in Older VeteransActive, not recruitingNCT04691986Not applicable