VA Office of Research and Development: Sleep Apnea Syndromes trials

The registry lists 36 Sleep Apnea Syndromes studies with VA Office of Research and Development as lead sponsor. 8 are open to participants now and 25 have results posted.

Early Phase 1 1Phase 1 3Phase 2 8Phase 3 4Phase 4 5No phase 21(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Central Apnea in Heart Failure: Physiological Mechanisms to Inform TreatmentRecruitingNCT07210606Phase 4
• Behavioral Optimization to Overcome Obstructive Sleep Apnea Treatment BarriersNot yet recruitingNCT07207473Not applicable
• DRonabinol Treatment of OSARecruitingNCT06477952Phase 1/2
• Sleep Disordered Breathing With Opioid UseRecruitingNCT05589753Phase 1/2
• Effect of Hypercapnia Treatment on Respiratory Recovery After Spinal Cord InjuryRecruitingNCT05536076Not applicable
• Impact of Positive Airway Pressure Therapy on Clinical Outcomes in Older Veterans With Chronic Obstructive Pulmonary Disease and Comorbid Obstructive Sleep Apnea (Overlap Syndrome)RecruitingNCT04179981Not applicable
• Central Sleep Apnea : Physiologic Mechanisms to Inform TreatmentRecruitingNCT04118387Phase 4
• Sleep Apnea in ElderlyRecruitingNCT02703220Phase 4
• Addressing Insufficient PAP Use in Older VeteransCompletedNCT04868682Not applicableResults posted
• Bright Light Therapy for Residual Daytime Symptoms Associated With Obstructive Sleep ApneaCompletedNCT04299009Not applicableResults posted
• Feasibility of Improving Sleep Apnea Treatment Adherence After Brain InjuryCompletedNCT04221009Not applicableResults posted
• Apnea and Insomnia Relief StudyCompletedNCT04007796Phase 2Results posted
• Self-Management of Continuous Positive Airway Pressure SettingsCompletedNCT03536572Not applicableResults posted
• Treating Sleep Apnea in Women VeteransCompletedNCT03377452Not applicableResults posted
• Remote Diagnosis and Management of Obstructive Sleep ApneaCompletedNCT03007745Not applicableResults posted
• Treatment of Sleep-disordered Breathing in Patients With SCICompletedNCT02830074Not applicableResults posted
• Influence of Exercise, Weight Loss, and Exercise Plus Weight Loss on Sleep ApneaTerminatedNCT02721251Not applicableResults posted
• Cognitive Behavioral Therapy to Increase CPAP Adherence in Veterans With PTSDCompletedNCT02641496Not applicableResults posted
• Role of Enhancing Serotonin Receptors Activity for Sleep Apnea Treatment in Patients With SCICompletedNCT02458469Phase 2Results posted
• Obstructive Sleep Apnea Treatment to Improve Cardiac RehabilitationTerminatedNCT02005445Not applicableResults posted
• Race And CPAP EffectivenessCompletedNCT01960465Not applicableResults posted
• Improving the Frequency and Quality of Sleep Apnea Care ManagementCompletedNCT01916655Not applicableResults posted
• Oxygen Versus PAP for Sleep Apnea in Heart FailureCompletedNCT01807897Phase 4Results posted
• A Randomized Cross Over Trial of Two Treatments for Sleep Apnea in Veterans With Post-Traumatic Stress DisorderCompletedNCT01569022Not applicableResults posted
• Inhaled Fluticasone Effects on Upper Airway Patency in Obstructive Lung DiseaseTerminatedNCT01554488Phase 4Results posted
• Using Telemedicine to Improve Veteran Sleep Apnea CareCompletedNCT01259440Phase 1/2Results posted
• Telemedicine Interventions for Obstructive Sleep Apnea (OSA)CompletedNCT01108081Phase 3Results posted
• Diagnosis and Treatment of Sleep Apnea in Cerebrovascular DiseaseCompletedNCT00984308Phase 2/3Results posted
• Respiratory and Autonomic Plasticity Following Intermittent HypoxiaCompletedNCT00860743Early Phase 1Results posted
• Determinants of Age Related Breathing Instability During Non-Rapid-Eye-Movement (NREM) SleepCompletedNCT00732199Not applicableResults posted
• Improving Obstructive Sleep Apnea Management Via Wireless TelemonitoringCompletedNCT00682838Phase 2/3Results posted
• Effect of Self-Management on Improving Sleep Apnea OutcomesCompletedNCT00310310Phase 2/3Results posted
• Telecommunications System in Sleep ApneaCompletedNCT00232544Not applicableResults posted
• Direct Referral for Apnea MonitoringCompletedNCT05419323
• Effect of Myofunctional Therapy on OSACompletedNCT04608552Not applicable
• Addressing Sleep Apnea Post-Stroke/TIAActive, not recruitingNCT04322162Not applicable