VA Office of Research and Development: Schizophrenia trials

The registry lists 48 Schizophrenia studies with VA Office of Research and Development as lead sponsor. 6 are open to participants now and 33 have results posted.

Early Phase 1 1Phase 1 4Phase 2 6Phase 3 2No phase 38(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Enhancing Veteran-Clinical Collaboration in VA PRRCsRecruitingNCT06898879Not applicable
• CBT-CP for Veterans With SMIRecruitingNCT06758414Not applicable
• Enhancing Rehabilitation for Veterans With Serious Mental IllnessRecruitingNCT06586164Not applicable
• Neurophysiologic Biomarkers for Cognitive RehabilitationRecruitingNCT05945602
• Acceptability and Feasibility of Work-Oriented Social-Cognitive Skills Training for Veterans With Serious Mental IllnessRecruitingNCT05491538Not applicable
• Exercise-based Program for Rehabilitation of Veterans With Severe Mental IllnessRecruitingNCT05157620Not applicable
• Mobile Self-Tracking of Mental HealthCompletedNCT05023252Not applicableResults posted
• Optimizing Cognitive RemediationCompletedNCT04395157Results posted
• Neuroplasticity in TBI and SchizophreniaCompletedNCT03995368Not applicableResults posted
• A Pharmaco-imaging Approach to Predicting Social Functioning and Clinical Responses to Oxytocin Administration in SchizophreniaTerminatedNCT03900754Phase 2Results posted
• Restoration of Cognitive Function With TDCS and Training in Serious Mental IllnessCompletedNCT03208036Not applicableResults posted
• Improving Neurocognitive Deficits and Function in Schizophrenia With Transcranial Magnetic StimulationCompletedNCT03037983Not applicableResults posted
• Reducing Hippocampal Hyperactivity and Improving Cognition in SchizophreniaCompletedNCT03034356Phase 1/2Results posted
• Benefits of Physical Exercise in SchizophreniaCompletedNCT02716584Not applicableResults posted
• Aerobic Exercise for Cognition in SchizophreniaCompletedNCT02621983Not applicableResults posted
• Improving Negative Symptoms & Community Engagement in Veterans With SchizophreniaCompletedNCT02469389Not applicableResults posted
• Motivational Negative Symptoms in Schizophrenia: Intervention and BiomarkersCompletedNCT02386605Not applicableResults posted
• Comparison of E-health vs. In-person Multi-Family Group (MFG)CompletedNCT02032680Not applicableResults posted
• Building Employment Skills Through Therapy for VeteransCompletedNCT01992913Not applicableResults posted
• Acceptance and Commitment Therapy for the Inpatient Treatment of PsychosisCompletedNCT01981356Early Phase 1Results posted
• Evaluating Two Types of Cognitive Training in Veterans With SchizophreniaCompletedNCT01891721Not applicableResults posted
• Get Moving and Get Well - Pilot StudyCompletedNCT01884025Not applicableResults posted
• PACT for Individuals With Serious Mental IllnessCompletedNCT01668355Not applicableResults posted
• PTSD (PostTraumatic Stress Disorder) Services for Veterans With SMI (Severe Mental Illness)CompletedNCT01542229Not applicableResults posted
• Life Goals Collaborative Care to Improve Health Outcomes in Mental DisordersCompletedNCT01487668Not applicableResults posted
• Reducing Internalized Stigma in People With Serious Mental IllnessCompletedNCT01259427Phase 2Results posted
• Remediation of Working Memory in SchizophreniaCompletedNCT00995553Not applicableResults posted
• Nicotinic Receptors and SchizophreniaCompletedNCT00952393Phase 1Results posted
• Neurophysiological Targets for Cognitive Training in SchizophreniaCompletedNCT00923078Not applicableResults posted
• Cognitive Behavior Therapy and Work OutcomeCompletedNCT00810355Not applicableResults posted
• Pregnenolone for Cognitive and Negative Symptoms in SchizophreniaCompletedNCT00728728Phase 2Results posted
• Cognitive-Behavioral Therapy in Veterans With SchizophreniaCompletedNCT00688259Not applicableResults posted
• Illness Management and Recovery for Veterans With Severe Mental IllnessCompletedNCT00515671Not applicableResults posted
• Improving Basic and Social Cognition in Veterans With SchizophreniaCompletedNCT00470106Not applicableResults posted
• The Use of Skills Training to Augment Compensated Work Therapy (CWT)/VI for Veterans With SMICompletedNCT00272168Not applicableResults posted
• Motivational Interviewing to Improve Work Outcomes in SchizophreniaCompletedNCT00261716Phase 3Results posted
• Cognitive Rehabilitation in SchizophreniaCompletedNCT00248794Not applicableResults posted
• Implementing Effective, Collaborative Care for Schizophrenia (EQUIP-2)CompletedNCT00137280Not applicableResults posted
• Genetic Research in Schizophrenia Using DNA Markers and Clinical PhenotypesCompletedNCT00108303Results posted
• Home-based Exercise for SMIWithdrawnNCT06078293Not applicable
• Alexithymia Intervention for SuicideTerminatedNCT05724953Phase 1
• Adapting and Examining Collaborative Decision Skills Training Among Veterans With Serious Mental IllnessCompletedNCT04324944Not applicable
• Assessment and Treatment for Chronic Pain in Veterans With Serious Mental IllnessCompletedNCT04118283Not applicable
• Rescuing the Ruminating Brain: Identifying Biomarkers of Rumination and Mindfulness Through Concurrent EEG and Functional Magnetic Resonance Imaging (fMRI) Studies of Schizophrenia and DepressionWithdrawnNCT03758495
• Evaluating the Use of Peer Specialists to Deliver Cognitive Behavioral Social Skills TrainingCompletedNCT03467243Not applicable
• Nicotinic Receptors and SchizophreniaWithdrawnNCT02538081Phase 1/2
• Life Goals Behavioral Change to Improve Outcomes for Veterans With Serious Mental IllnessCompletedNCT01244854Not applicable
• Work Activity Augmented by Cognitive Rehabilitation for SchizophreniaCompletedNCT00430560Phase 2/3