VA Office of Research and Development: Alzheimer Disease trials

The registry lists 14 Alzheimer Disease studies with VA Office of Research and Development as lead sponsor. 1 are open to participants now and 11 have results posted.

Phase 1 1Phase 2 4Phase 3 2Phase 4 3No phase 6(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Contributions of mTBI to Neurodegeneration Due to Chronic Traumatic Encephalopathy (CTE) and Alzheimer's Disease (AD)RecruitingNCT04124029
• Brain Amyloid and Vascular Effects of Eicosapentaenoic AcidCompletedNCT02719327Phase 2/3Results posted
• Optimizing Dementia CareCompletedNCT02585232Not applicableResults posted
• Preventing Loss of Independence Through Exercise (PLIE) in Persons With DementiaCompletedNCT02350127Phase 2/3Results posted
• Promoting Adaptive Neuroplasticity in Mild Cognitive ImpairmentCompletedNCT02155946Not applicableResults posted
• Enhancing Spatial Navigation Using Non-Invasive Brain StimulationCompletedNCT01958437Not applicableResults posted
• Semantic Memory, Financial Capacity, and Brain Perfusion in Mild Cognitive Impairment (MCI) (CASL)CompletedNCT00880555Results posted
• Behavioral and Neuroimaging Changes After Cognitive Rehab in Traumatic Brain Injuries (TBI) and Mild Cognitive Impairment (MCI)CompletedNCT00714571Phase 1Results posted
• Methylphenidate for Apathy in Alzheimer's Dementia: A Controlled StudyCompletedNCT00495820Phase 4Results posted
• Development of NIC5-15 in the Treatment of Alzheimer's DiseaseCompletedNCT00470418Phase 2Results posted
• Low-Dose Opiate Therapy for Discomfort in Dementia (L-DOT)CompletedNCT00385684Phase 4Results posted
• Partners in Dementia Care: A Telephone Care Consultation Intervention Provided to Veterans in Partnership With Local Alzheimer's Association ChaptersCompletedNCT00291161Not applicableResults posted
• Water-based Activity to Enhance Recall in Veterans: A Randomized Clinical TrialCompletedNCT04296565Phase 4
• Curcumin and Yoga Therapy for Those at Risk for Alzheimer's DiseaseStatus unknownNCT01811381Phase 2