VA Office of Research and Development: Depressive Disorder trials

The registry lists 33 Depressive Disorder studies with VA Office of Research and Development as lead sponsor. 1 are open to participants now and 25 have results posted.

Phase 1 1Phase 2 4Phase 3 4Phase 4 1No phase 25(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• ACT for Veterans With IBD and Mental Health ChallengesNot yet recruitingNCT07397195Not applicable
• Comparing Group Therapies for Veterans With Depression and PTSDCompletedNCT03979040Not applicableResults posted
• Pilot Study of Annie Text Messaging for Depression Treatment AdherenceCompletedNCT03930849Not applicableResults posted
• Improving Outcomes for Older Veterans With Chronic Back Pain and DepressionCompletedNCT03896035Not applicableResults posted
• A Randomized Control Trial Treating Depression With Yoga and Coherent Breathing Versus Walking in VeteransTerminatedNCT03489122Not applicableResults posted
• Implementing a Blended Care Model That Integrates Mental Healthcare and Primary Care Using Telemedicine and Care Management for Patients With Depression or Alcohol Use Disorder in Small Primary Care ClinicsCompletedNCT02713217Results posted
• Ketamine for Treatment Resistant Late-Life DepressionCompletedNCT02556606Phase 3Results posted
• Telehealth Cognitive Behavioral Therapy for Depression in Parkinson's Disease (PD)CompletedNCT02475954Not applicableResults posted
• Ketamine for the Rapid Treatment of Major Depressive Disorder and Alcohol Use DisorderCompletedNCT02461927Phase 1/2Results posted
• Supported Employment in Patient Aligned Care TeamsCompletedNCT02400736Not applicableResults posted
• Efficacy of Repeated Ketamine Infusions for Treatment-resistant DepressionCompletedNCT02360280Phase 2Results posted
• Improving Mood in Veterans in Primary CareCompletedNCT02276807Not applicableResults posted
• Reducing the Burden of Depression Related DisabilityCompletedNCT02111811Not applicableResults posted
• Veteran Peer-Assisted Computerized Cognitive Behavioral Therapy for DepressionCompletedNCT02057042Not applicableResults posted
• Transdiagnostic Psychotherapy for Veterans With Mood and Anxiety DisordersCompletedNCT01947647Not applicableResults posted
• Lithium for Suicidal Behavior in Mood DisordersTerminatedNCT01928446Phase 2/3Results posted
• Behavioral Activation Therapy for Rural Veterans With Diabetes and DepressionCompletedNCT01572389Not applicableResults posted
• Life Goals Collaborative Care to Improve Health Outcomes in Mental DisordersCompletedNCT01487668Not applicableResults posted
• VA Augmentation and Switching Treatments for Improving Depression OutcomesCompletedNCT01421342Phase 3Results posted
• The Effectiveness of rTMS in Depressed VA PatientsCompletedNCT01191333Not applicableResults posted
• Hepatitis C Translating Initiatives for Depression Into Effective SolutionsCompletedNCT01143896Not applicableResults posted
• Project SERVE: Post Deployment FunctioningCompletedNCT01123642Results posted
• Chronic Kidney Disease Antidepressant Sertraline TrialCompletedNCT00946998Phase 3Results posted
• Behavioral Activation for PTSD/Depression Treatment in OIF/OEF VeteransCompletedNCT00805532Not applicableResults posted
• Regional Anesthesia Military Battlefield Pain Outcomes StudyCompletedNCT00431847Results posted
• Depression and Congestive Heart Failure in Outpatients.CompletedNCT00321269Not applicableResults posted
• VA Aripiprazole vs Esketamine for Treatment Resistant DepressionWithdrawnNCT05554627Phase 4
• Whole Health in VA Mental Health: Omnis SalutisActive, not recruitingNCT05400252Not applicable
• Reducing Suicide Risk in Older Veterans Using Problem Solving TherapyTerminatedNCT04763330Not applicable
• Imaging to Improve Brain StimulationCompletedNCT04016402
• Rescuing the Ruminating Brain: Identifying Biomarkers of Rumination and Mindfulness Through Concurrent EEG and Functional Magnetic Resonance Imaging (fMRI) Studies of Schizophrenia and DepressionWithdrawnNCT03758495
• Life Goals Behavioral Change to Improve Outcomes for Veterans With Serious Mental IllnessCompletedNCT01244854Not applicable
• Integrated Intervention for Substance Abusers With Depressive DisordersCompletedNCT00018655Phase 2