VA Office of Research and Development: Sleep Initiation and Maintenance Disorders trials

The registry lists 43 Sleep Initiation and Maintenance Disorders studies with VA Office of Research and Development as lead sponsor. 10 are open to participants now and 28 have results posted.

Phase 2 2Phase 3 1Phase 4 2No phase 38(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Sleep MAPP in the Polytrauma/TBI System of CareNot yet recruitingNCT07886398Not applicable
• SleepSMART for Veterans With Insomnia and Mild Cognitive ImpairmentNot yet recruitingNCT07397182Not applicable
• Implementing Cognitive Behavioral Therapy for Insomnia (SWELL): Function QUERI 3.0RecruitingNCT07216261Not applicable
• The Effects of Orexin Antagonism on Fear Extinction in PTSDNot yet recruitingNCT06788522Phase 4
• A Transdiagnostic Sleep Health Intervention for Veterans With PTSDNot yet recruitingNCT06549049Not applicable
• Predictors of Post-COVID-19 Clinical and Cognitive ConsequencesRecruitingNCT06291870
• Brief Behavioral Treatment for Insomnia in Veterans With Posttraumatic Stress DisorderRecruitingNCT05780177Not applicable
• Pimavanserin for Insomnia in Veterans With PTSDRecruitingNCT05441280Phase 2
• Treatments for Insomnia in Veterans With PTSDRecruitingNCT05194930Not applicable
• Suvorexant: A Dual Orexin Receptor Antagonist for Treating Sleep Disturbance in Posttraumatic StressRecruitingNCT03642028Phase 4
• The Feasibility of Home-Based Measurement of Circadian Timing for Veterans With TBI and InsomniaCompletedNCT05665764Results posted
• MIDAS Cluster Randomized Controlled Trial of Implementation Strategies to Optimize Use of Medications in VA Clinical SettingsCompletedNCT05065502Not applicableResults posted
• Reducing Use of Sleep Medications Assisted by a Digital Insomnia InterventionCompletedNCT05027438Not applicableResults posted
• SleepSMART for Veterans With MCI and InsomniaCompletedNCT05016960Not applicableResults posted
• Internet-based Cognitive-behavioral Treatment for Insomnia in COPD Patients Undergoing Pulmonary RehabilitationCompletedNCT04700098Not applicableResults posted
• Promoting Benzodiazepine Cessation Through an Electronically-delivered Patient Self-management InterventionCompletedNCT04572750Not applicableResults posted
• Enhancing Access to Insomnia (EASI) Care in VA PCMHI ClinicsCompletedNCT04350866Results posted
• Neurofeedback Impact on Veterans With mTBICompletedNCT04195685Not applicableResults posted
• Apnea and Insomnia Relief StudyCompletedNCT04007796Phase 2Results posted
• Tele-Self CBTI TrialCompletedNCT03727438Not applicableResults posted
• RCT of Brief CBT-I in Primary Care Veterans With Suicidal ThoughtsCompletedNCT03603717Not applicableResults posted
• Non-Pharmacological Treatments for Insomnia in Chronic Traumatic Brain InjuryCompletedNCT03261674Not applicableResults posted
• Predictors of Response to Insomnia Treatments for Gulf War VeteransCompletedNCT03208049Not applicableResults posted
• Implementing and Evaluating Computer-Based Interventions for Mental Health: Testing an Implementation Strategy for VA Outpatient CareCompletedNCT03151083Not applicableResults posted
• Cognitive Behavioral Therapy for Insomnia for Gulf War IllnessCompletedNCT02782780Not applicableResults posted
• Integrated CBT-I and PE on Sleep and PTSD Outcomes (Impact Study)CompletedNCT02774642Not applicableResults posted
• Cognitive-Behavioral Therapy for Veterans With TBICompletedNCT02658669Not applicableResults posted
• Brief Behavioral Insomnia Treatment StudyCompletedNCT02571452Not applicableResults posted
• Mobile Sleep Intervention for OEF, OIF and OND VeteransCompletedNCT02392000Not applicableResults posted
• Adjunctive Brief Behavioral Treatment of Insomnia (BBTI) for Sleep Intervention (SI)CompletedNCT02248675Not applicableResults posted
• CBT-I for Cannabis UseTerminatedNCT02102230Not applicableResults posted
• Insomnia Treatment for Women VeteransCompletedNCT02076165Not applicableResults posted
• Novel Treatment of Comorbid Insomnia and Sleep Apnea in Older VeteransCompletedNCT02027558Not applicableResults posted
• The Efficacy of CBT-I in Alcoholics & Its Effects on Remission & RelapseCompletedNCT01987089Not applicableResults posted
• Telemedicine Management of Chronic InsomniaCompletedNCT01686438Not applicableResults posted
• Toileting at Night in Older Adults: Light to Maximize Balance, Minimize InsomniaCompletedNCT01350505Not applicableResults posted
• AcuSleep in Mild Traumatic Brain Injury (TBI)CompletedNCT01162317Not applicableResults posted
• Implementing Sleep Interventions for Older VeteransCompletedNCT00781963Not applicableResults posted
• Brief Versus Standard Cognitive Behavioral Therapy for Insomnia in VeteransTerminatedNCT05724498Not applicable
• Treatments in Women Veterans With Insomnia and PTSDActive, not recruitingNCT05683132Not applicable
• The DigIT Trial: The Effectiveness and Implementation of a Coached Digital Insomnia Treatment Program in a Regional Healthcare System.CompletedNCT05558475Not applicable
• CBT-I to Improve Functional Outcomes in Veterans With PsychosisActive, not recruitingNCT04646200Not applicable
• National Adaptive Trial for PTSD Related InsomniaCompletedNCT03668041Phase 3