VA Office of Research and Development: Heart Failure trials

The registry lists 36 Heart Failure studies with VA Office of Research and Development as lead sponsor. 5 are open to participants now and 27 have results posted.

Early Phase 1 2Phase 2 4Phase 3 2Phase 4 2No phase 28(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Virtual Nurse and Social Worker Palliative Care Team to Improve Quality of Life in Veterans With Heart Failure or COPDEnrolling by invitationNCT07714252Not applicable
• Pharmacist-Assisted Titration of Rx to Implement Optimal Medical Therapy for Heart FailureNot yet recruitingNCT07714239Not applicable
• Central Apnea in Heart Failure: Physiological Mechanisms to Inform TreatmentRecruitingNCT07210606Phase 4
• CSP #2025 - Geriatric OUt-of-hospital Randomized MEal Trial in Heart Failure: Veterans Affairs (GOURMET-VA)RecruitingNCT05996328Not applicable
• Remote Ischemic Preconditioning for Renal and Cardiac Protection in Congestive Heart Failure (RICH) TrialRecruitingNCT04982419Phase 2/3
• Informational Nudge to Improve Heart Failure PrescribingCompletedNCT05986695Not applicableResults posted
• Goals of Care Conversations StudyCompletedNCT05001009Not applicableResults posted
• The Re-Prosper HF StudyCompletedNCT04551222Phase 2/3Results posted
• LINK-HF2 - Remote Monitoring Analytics in Heart FailureCompletedNCT04502563Not applicableResults posted
• Exercise Therapy to Reduce Heart Failure Symptoms; Sorting Mechanisms of BenefitCompletedNCT03648762Not applicableResults posted
• Dietary Prevention of Heart Failure in Hypertensive Metabolic SyndromeCompletedNCT03170375Not applicableResults posted
• Advancing Symptom Alleviation With Palliative TreatmentCompletedNCT02713347Not applicableResults posted
• Group Medical Visits in Heart FailureCompletedNCT02481921Not applicableResults posted
• Exercise Training in Heart Failure: Changes in Cardiac Structure and FunctionCompletedNCT02275819Not applicableResults posted
• Biomarker Guided Therapies in Stage A/B Heart FailureCompletedNCT02230891Phase 2Results posted
• Premature Fatigue in Veterans With Heart Failure: Neuronal InfluencesCompletedNCT02209610Early Phase 1Results posted
• Contribution of Endothelin-1 to Exercise Intolerance in Heart FailureCompletedNCT02124824Early Phase 1Results posted
• Efficacy and Safety of Implantable Cardioverter-Defibrillator (ICD) Implantation in the ElderlyTerminatedNCT02121158Not applicableResults posted
• Oxygen Versus PAP for Sleep Apnea in Heart FailureCompletedNCT01807897Phase 4Results posted
• Caregiver Outlook: An Intervention to Improve Caregiving in Serious IllnessCompletedNCT01672294Not applicableResults posted
• Targeted Intervention to Improve Medication Adherence in Cognitively Impaired Patients With HF (TARGET)CompletedNCT01602731Not applicableResults posted
• Improving Symptoms and Quality of Life in Chronic Heart Failure: Pilot StudyCompletedNCT01581008Not applicableResults posted
• Effects of Exercise Training on Fluid Instability in Heart Failure PatientsCompletedNCT01375673Not applicableResults posted
• "Hub and Satellite" Heart Failure Provider's Network StudyCompletedNCT01246050Not applicableResults posted
• Adjusting to Chronic Conditions Using Education, Support, and SkillsCompletedNCT01149772Not applicableResults posted
• Veterans Affairs Lowering Readmission in Heart FailureCompletedNCT01144182Not applicableResults posted
• Outlook Quality of Life Intervention StudyCompletedNCT01044290Not applicableResults posted
• Outlook Quality of Life InterventionCompletedNCT00784095Not applicableResults posted
• An Intervention to Improve Function in Severe Cardiopulmonary IllnessCompletedNCT00467298Not applicableResults posted
• Patient-Centered Heart Failure TrialCompletedNCT00461513Results posted
• Depression and Congestive Heart Failure in Outpatients.CompletedNCT00321269Not applicableResults posted
• A Culturally Sensitive Values-Guided Aid for End of Life Decision-MakingCompletedNCT00122135Not applicableResults posted
• Allopurinol Improves Heart Function in African Americans With Resistant HypertensionCompletedNCT05888233Phase 2
• Evaluation of Left Bundle Branch Area Pacing As A Rescue Strategy for Cardiac Resynchronization Therapy Non-ResponseWithdrawnNCT05884411Not applicable
• Diagnostic Potential of UCHL1 in Acute Decompensated Heart FailureCompletedNCT04999995
• Patient Activation in High-Risk Patients With Heart FailureCompletedNCT00260650Not applicable