Mayo Clinic: Oropharyngeal Neoplasms trials

The registry lists 11 Oropharyngeal Neoplasms studies with Mayo Clinic as lead sponsor. 3 are open to participants now and 3 have results posted.

Phase 1 1Phase 2 5Phase 3 1No phase 5(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Methotrexate, Erlotinib, and Celecoxib for the Treatment of Recurrent/Metastatic Head and Neck Cancer in a Rural Midwest United States PopulationRecruitingNCT06997068Phase 2
• Oropharynx (OPX) Biomarker TrialRecruitingNCT06356272
• De-Escalated Adjuvant and Definitive Radiation Therapy Informed by DART 2.0 ctHPV-DNARecruitingNCT05541016Phase 2
• A Vaccine (PDS0101) Alone or in Combination With Pembrolizumab for the Treatment of Locally Advanced Human Papillomavirus-Associated Oropharynx CancerActive, not recruitingNCT05232851Phase 1/2Results posted
• Evaluation of De-escalated Adjuvant Radiation Therapy for Human Papillomavirus (HPV)-Associated Oropharynx CancerCompletedNCT02908477Phase 3Results posted
• Acetylcysteine Rinse in Reducing Saliva Thickness and Mucositis in Patients With Head and Neck Cancer Undergoing Radiation TherapyCompletedNCT02123511Phase 2Results posted
• A Pneumatic Compression Device for the Treatment of Lymphedema in Patients With Stage II-IV Head and Neck Cancer After ChemoradiationWithdrawnNCT05512767Not applicable
• Intensity Modulated Proton or X-Ray Therapy After Surgery for Treatment of Head and Neck Cancer, the HEADLIGHT StudyActive, not recruitingNCT05075980Phase 2
• Study of Mucosal Sparing Adjuvant Radiotherapy After Surgical Exploration in HPV+ Head and Neck Cancer of Unknown PrimariesCompletedNCT04489212Not applicable
• Robotic Surgery in the Seated Position for Benign and Malignant Lesions of the Head and NeckCompletedNCT02792322Not applicable
• A Study of Mucosal Sparing Proton Beam Therapy (PBT) in Resected Oropharyngeal TumorsCompletedNCT02736786