Mayo Clinic: Insulin Resistance trials

The registry lists 23 Insulin Resistance studies with Mayo Clinic as lead sponsor. 3 are open to participants now and 6 have results posted.

Early Phase 1 1Phase 1 3Phase 2 4Phase 3 1No phase 14(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Comparison of Neuromuscular Recruitment in Trained and Untrained AdultsRecruitingNCT06820658
• Investigating the Link Between Type 2 Immunity and NAFLD in Human ObesityRecruitingNCT04232566
• Intramyocellular Fatty Acid Trafficking in Insulin Resistance States - Effects of Intestinal Delivery of LipidsRecruitingNCT03818178Not applicable
• Molecular Mechanisms of Exercise Benefits to Insulin Resistant PeopleCompletedNCT04158375Not applicableResults posted
• Metformin Effect on Brain Function in Insulin Resistant Elderly PeopleCompletedNCT03733132Phase 2Results posted
• Ursodiol on Insulin Sensitivity, Gastric Emptying and Body Weight With Type 2 Diabetes on MetforminCompletedNCT02033876Phase 2Results posted
• Omega-3 Fatty Acids and Insulin SensitivityCompletedNCT01686568Phase 3Results posted
• Effect of Vitamin D3 Supplementation on Insulin Resistance and Cardiovascular Risk Factors in Obese AdolescentsCompletedNCT00858247Phase 2Results posted
• Effect of Insulin Sensitizer Therapy on Atherothrombotic and Inflammatory Profiles Associated With Insulin ResistanceCompletedNCT00443755Phase 2Results posted
• Extracellular Vesicle Cargo in Obesity and Type 2 DiabetesCompletedNCT06401876
• IL-4 and Insulin Resistance for Treatment of Patients With Atopic DermatitisCompletedNCT05372003Early Phase 1
• Eosinophils in Human Adipose TissueCompletedNCT04898400Not applicable
• Preoperative Oral Carbohydrate Drink for Elective Cesarean Delivery and the Effect on Insulin SensitivityTerminatedNCT03494868Not applicable
• Understanding the Relationship Between Inflammation and Insulin Resistance in the Adipose TissueCompletedNCT02378077Not applicable
• Potential Impact of Polycystic Ovarian Syndrome on Protein Modifications and AccumulationCompletedNCT02105428Not applicable
• Metformin's Effect on Glucagon-induced Glucose Production and Protein Metabolism.CompletedNCT01956929Phase 1
• Plasma Triglyceride Extraction by The MuscleCompletedNCT01860911Phase 1
• Epigenetics and the Origin of Muscle Insulin Resistance in HumansCompletedNCT01726491
• Does Class of Dietary Fat Affect Insulin Resistance?CompletedNCT01541592Not applicable
• Effects of Calorie Restriction on Accumulation of Old, Modified Proteins in Abdominally Obese AdultsCompletedNCT01497106Not applicable
• Impact of Muscle Insulin Resistance on the Pathogenesis of Non Alcoholic SteatohepatitisCompletedNCT01324414
• Insulin Receptor Substrate 1 (IRS-1) Regulation in Insulin ResistanceCompletedNCT01240252Phase 1
• Production of Free Fatty Acids From Blood TriglyceridesCompletedNCT00911482