Mayo Clinic: Cholangitis, Sclerosing trials

The registry lists 15 Cholangitis, Sclerosing studies with Mayo Clinic as lead sponsor. 4 are open to participants now and 2 have results posted.

Phase 1 5Phase 2 4No phase 6(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Nemolizumab for the Treatment of Moderate to Severe Chronic Hepatic PruritusNot yet recruitingNCT07843420Phase 2
• Pharmacologic Approaches to Preventing Primary Sclerosing Cholangitis Recurrence After Liver TransplantationRecruitingNCT06905054Phase 2
• Characterization of Biliary Cell-derived Organoids From Bile of PSC and Non-PSC PatientsRecruitingNCT04753996
• Biobank for Cholestatic Liver Diseases.RecruitingNCT03445585
• A Pilot Study of Vancomycin or Metronidazole in Patients With Primary Sclerosing CholangitisCompletedNCT01085760Phase 1Results posted
• Thalidomide for the Treatment of Primary Sclerosing Cholangitis (PSC)TerminatedNCT00953615Phase 2Results posted
• Treatment of IgG4-Related Disease With Revlimid and RituximabCompletedNCT02705638Phase 1
• Bile Usefulness for Detecting IgG4-related Sclerosing CholangitisCompletedNCT02616705
• A Pilot Study of Xifaxan to Treat Patients With PSCCompletedNCT01695174Phase 1
• Genomics of Primary Sclerosing Cholangitis (PSC)CompletedNCT01161992
• Erlotinib for Chemoprevention in Trisomy 7 Positive Primary Sclerosing Cholangitis (PSC)CompletedNCT00955149Phase 1
• Cholangioscopy Using Narrow Band Imaging (NBI) in Patients With Primary Sclerosing Cholangitis (PSC) Undergoing Endoscopic Retrograde Cholangiopancreatogram (ERCP)CompletedNCT00951327
• Minocycline in Primary Sclerosing Cholangitis (PSC)CompletedNCT00630942Phase 1
• The Value of CT Cholangiography in Primary Sclerosing CholangitisWithdrawnNCT00588458Phase 2
• Compare Conventional Colonosocpy to Endoscopic AFI, NBI for Dysplasia Detection for Ulcerative Colitis & CholangitisCompletedNCT00587236