Mayo Clinic: Depression trials

The registry lists 31 Depression studies with Mayo Clinic as lead sponsor. 4 are open to participants now and 8 have results posted.

Phase 1 1Phase 2 3Phase 3 1Phase 4 1No phase 25(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Mindfulness and Meditation Based Lactation Education on Maternal Breastmilk in the Neonatal ICURecruitingNCT07351799Not applicable
• Virtual Reality Intervention to Improve Psychological Symptom Burden for Cancer Patients Undergoing TreatmentRecruitingNCT07221409Not applicable
• Evaluating the Effects of a Fermented Diet on Microbiome Diversity in Individuals With Long COVIDEnrolling by invitationNCT06560554Not applicable
• Effect of Vagal Nerve Stimulation on Gastric Motor FunctionsRecruitingNCT06038929Not applicable
• The BIO-K Study: A Single-Arm, Open-Label, Biomarker Development Clinical Trial of Ketamine for Non-Psychotic Unipolar Major Depression and Bipolar I or II Depression.CompletedNCT03156504Phase 4Results posted
• Ketamine for Depression and Suicide RiskCompletedNCT02094898Phase 2Results posted
• Oral Ketamine in the Treatment of Depression and Anxiety in Patients With CancerTerminatedNCT01680172Phase 2Results posted
• Evaluation of an Antidepressant Pharmacogenomic Algorithm in an Outpatient Clinical SettingCompletedNCT01610063Not applicableResults posted
• Ketamine Anesthesia in Electroconvulsive TherapyCompletedNCT01367119Not applicableResults posted
• Study of Repetitive Transcranial Magnetic Stimulation (rTMS) as Adjuvant Treatment for DepressionTerminatedNCT01115699Not applicableResults posted
• Bipolar Depression Before and After Lamotrigine TreatmentCompletedNCT01042496Phase 3Results posted
• An Evaluation of Safety and Feasibility Using Repetitive Transcranial Magnetic Stimulation (rTMS) in Adolescents With DepressionCompletedNCT00587639Not applicableResults posted
• A Study of Ketamine Infusions to Treat Clinically-depressed ICU PatientsTerminatedNCT05803551Phase 2
• Aloud Real-time Reading of ICU Diaries for Prevention of Negative Post-ICU Psychological OutcomesCompletedNCT04510272Not applicable
• Positive Suggestions Via MP3 MessagesCompletedNCT04437095Not applicable
• Stress Management and Resiliency Training for Depression vs Treatment as Usual in the Treatment of Major DepressionCompletedNCT04388748Not applicable
• Augmented Human Intelligence in Major Depressive DisorderCompletedNCT04355650Not applicable
• ICU Doulas Providing Psychological SupportCompletedNCT03736954Not applicable
• Stress Management and Resiliency Training (SMART) Integrated Into Treatment of Major DepressionCompletedNCT03275961Not applicable
• Effectiveness and Satisfaction With Brief Synchronous Tele-psychiatry ConsultWithdrawnNCT02967835Not applicable
• Clinical Impact of the Antidepressant Pharmacogenomic Algorithm in an Outpatient Therapy-based Clinical SettingCompletedNCT02479464Not applicable
• Glutamate Probes in Adolescent DepressionCompletedNCT02307617
• A PK/PD Genetic Variation Treatment Algorithm Versus Treatment As Usual for Adolescent Management Of DepressionCompletedNCT02286440Not applicable
• A Pharmacokinetic/Pharmacodynamic Genetic Variation Treatment Algorithm Versus Treatment As Usual for Management Of DepressionCompletedNCT02189057Not applicable
• Vigorous Exercise for Depressed SmokersCompletedNCT01860924Not applicable
• Cortical Excitability and Inhibition in MDDCompletedNCT01718730
• Acceleration and Relapse Prevention With Triiodothyronine (T3) as an Adjunct to Electroconvulsive Therapy (ECT)CompletedNCT01299337
• Cognitive Behavioral Therapy, Self-Efficacy, and Depression in Persons With Chronic PainCompletedNCT01055665
• Interpersonal and Social Rhythm Therapy Enter the Brief Title for Protocol IRB 09-003781>CompletedNCT01037283Not applicable
• Tamoxifen in Women With Breast Cancer and in Women at High-Risk of Breast Cancer Who Are Receiving Venlafaxine, Citalopram, Escitalopram, Gabapentin, or SertralineCompletedNCT00667121
• Pharmacodynamics and Pharmacokinetics of Citalopram and EscitalopramCompletedNCT00613470Phase 1