Mayo Clinic: Amyotrophic Lateral Sclerosis trials

The registry lists 10 Amyotrophic Lateral Sclerosis studies with Mayo Clinic as lead sponsor. 3 are open to participants now and 2 have results posted.

Early Phase 1 1Phase 1 2Phase 2 1Phase 3 1No phase 5(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Studies in Amyotrophic Lateral Sclerosis (ALS) and Other Neurodegenerative Motor Neuron DisordersRecruitingNCT05474235
• Biospecimen Biorepository for the Study of ALS, ALS-FTD and Similar Neurodegenerative DisordersRecruitingNCT05116943
• ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)RecruitingNCT04363684
• Intrathecal Autologous Adipose-derived Mesenchymal Stromal Cells for Amyotrophic Lateral Sclerosis (ALS)Active, not recruitingNCT03268603Phase 2Results posted
• Insulin-like Growth Factor-1 in Amyotrophic Lateral Sclerosis (ALS) TrialCompletedNCT00035815Phase 3Results posted
• Xavier Electromyographic Wheelchair Control for Limited Mobility PatientsCompletedNCT04800926Not applicable
• Perampanel Single Ascending Dose Transcranial Magnetic Stimulation Biomarker Study in Amyotrophic Lateral SclerosisCompletedNCT03793868Early Phase 1
• DNA, Blood and Skin Cell Repository for Research on ALS and Related Neurodegenerative Disorders at Mayo Clinic FloridaCompletedNCT01699451
• A Dose-escalation Safety Trial for Intrathecal Autologous Mesenchymal Stem Cell Therapy in Amyotrophic Lateral SclerosisCompletedNCT01609283Phase 1
• Mesenchymal Stem Cells for Treatment of Amyotrophic Lateral Sclerosis (ALS)CompletedNCT01142856Phase 1