Mayo Clinic: Obesity trials

The registry lists 60 Obesity studies with Mayo Clinic as lead sponsor. 16 are open to participants now and 19 have results posted.

Early Phase 1 4Phase 1 5Phase 2 5Phase 3 3Phase 4 12No phase 32(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• The Effect of Tirzepatide on Menopausal Vasomotor Symptoms and Biological Aging in Post-menopausal Women With ObesityRecruitingNCT07218445Phase 4
• Individualized Pharmacological Approach to Obesity in Patients With Bipolar DisorderRecruitingNCT07213466Phase 4
• Aging Well: Targeting Obesity With GLP-1 Agonists to Enhance Physical and Vascular Health in Postmenopausal WomenEnrolling by invitationNCT07057310Phase 4
• Upper Body Subcutaneous Exosome Release in Response to a Meal in ObesityRecruitingNCT07031297Not applicable
• Circadian Rhythms in Human AdiposeRecruitingNCT06891534Not applicable
• Weight Loss Through Mayo Clinic DietRecruitingNCT06862375Not applicable
• Knee Injections for Obese Patients With Knee ArthritisRecruitingNCT06782529Phase 4
• Phenotype-Tailored Lifestyle Intervention for Obesity: A Randomized TrialRecruitingNCT06770049Not applicable
• Regional Lipolysis and Adipocyte Lipolysis Protein StimulationRecruitingNCT06416969Early Phase 1
• Regional Lipolysis Insulin RegulationRecruitingNCT06392854Early Phase 1
• Exercise Response in Humans With ObesityRecruitingNCT05857150
• Dietary Sugar Absorptive Phenotype for Prediction of Weight Loss OutcomeEnrolling by invitationNCT05408728
• Evaluating Benefit of Peptide Based Diet in Obese HEN PatientsEnrolling by invitationNCT05080699Not applicable
• Antibiotic Prophylaxis in High-Risk Arthroplasty PatientsEnrolling by invitationNCT04297592Phase 4
• Investigating the Link Between Type 2 Immunity and NAFLD in Human ObesityRecruitingNCT04232566
• Insulin Regulation of Lipolysis and Lipolysis ProteinsRecruitingNCT03866408Early Phase 1
• A Study of Endoscopic Sleeve Gastroplasty for Obesity in Ulcerative ColitisActive, not recruitingNCT05739162Not applicableResults posted
• Hybrid Argon Plasma Coagulation and Endoscopic Sleeve Gastroplasty TrialCompletedNCT05559866Not applicableResults posted
• Lifestyle Program for Obstructive Sleep Apnea With Severe ObesityCompletedNCT05343000Not applicableResults posted
• Effect of Bile Acids on Satiety, Cell Function and Body Weight in Patients With Obesity and Abnormal Satiety PhenotypeCompletedNCT05314374Phase 1Results posted
• Regulation of Muscle Protein Phenotype in Humans With ObesityCompletedNCT04700800Not applicableResults posted
• Anti-Obesity Phentermine-Topiramate Extended Release Pharmacotherapy vs Placebo Among Patients Using a Wearable Activity TrackerCompletedNCT04408586Phase 4Results posted
• Molecular Mechanisms of Exercise Benefits to Insulin Resistant PeopleCompletedNCT04158375Not applicableResults posted
• Effects of Niacin on Intramyocellular Fatty Acid Trafficking in Upper Body Obesity and Type 2 Diabetes MellitusCompletedNCT03867500Early Phase 1Results posted
• Metformin Effect on Brain Function in Insulin Resistant Elderly PeopleCompletedNCT03733132Phase 2Results posted
• Individualized Obesity PharmacotherapyCompletedNCT03374956Phase 3Results posted
• Characterization of Bile Acid Pathway in ObesityCompletedNCT03341052Not applicableResults posted
• Dermatome Electrical Stimulation on Individuals With Overweight and Class I ObesityTerminatedNCT03261531Not applicableResults posted
• EUS Guided Core Liver Biopsy and IGB Placement for the Diagnosis and Management of NASH and ObesityCompletedNCT02880189Not applicableResults posted
• Pilot Study of the Effect of Liraglutide on Weight Loss and Gastric Functions in ObesityCompletedNCT02647944Phase 2Results posted
• Effect of Exenatide in Obese Patients With Accelerated Gastric EmptyingCompletedNCT02160990Phase 4Results posted
• Peripheral Pharmacodynamics of Phentermine-Topiramate in Obese PatientsCompletedNCT01834404Phase 4Results posted
• Portion Control Treatment for ObesityCompletedNCT01451554Phase 2/3Results posted
• Vagal Nerve Stimulation and Glucose MetabolismCompletedNCT01117311Not applicableResults posted
• Effect of Vitamin D3 Supplementation on Insulin Resistance and Cardiovascular Risk Factors in Obese AdolescentsCompletedNCT00858247Phase 2Results posted
• A Study of a Novel Precision Medicine Approach For ObesityActive, not recruitingNCT06814938Phase 4
• Effects of Long-Acting GLP-1 (Glucagon-like Peptide-1) or Dual Incretin (GLP-1 and GIP [Glucose-dependent Insulinotropic Peptide]) Modulation on Gastric Motor FunctionsActive, not recruitingNCT06801015Phase 4
• The Weight of Cardiovascular DiseaseActive, not recruitingNCT06053645
• A Study of Adipose Tissue in Adaptive Responses to ExerciseActive, not recruitingNCT06053125Not applicable
• Cardiac and Metabolic Effects of Semaglutide in Heart Failure With Preserved Ejection FractionCompletedNCT05371496Phase 4
• Glucagon Suppression by Hyperglycemia in the Presence and Absence of Amino Acid InfusionActive, not recruitingNCT05264727Phase 4
• Eosinophils in Human Adipose TissueCompletedNCT04898400Not applicable
• Telemedicine Follow-up for Bariatric Surgery Patients: What Do Patients PreferTerminatedNCT04784286Not applicable
• Primary Care Referrals to Community-based Lifestyle Programs for Management of ObesityCompletedNCT04433806Not applicable
• Investigating the Effect of Obesity on Eosinophil Recruitment in Human Adipose TissueCompletedNCT04234295Not applicable
• Individualized Lifestyle Intervention for Obesity Management Based on Obesity PhenotypesCompletedNCT04073394Not applicable
• Connected Health Care in Exercise Program for ObesityCompletedNCT03446235Not applicable
• Bariatric Surgery Versus Diet Alone in the Bile Acid Pathway and Weight LossActive, not recruitingNCT03238794Not applicable
• Defining the Role of the Gut Microbiome in Mediating the Effects of Obesity on Intestinal Stem CellsTerminatedNCT02863029Not applicable
• Telecoaching Plus a Portion Control Device for Weight Management in the Primary Care SettingCompletedNCT02373878Not applicable
• Muscle Protein Metabolism in ObesityCompletedNCT01824173Phase 1
• Endoscopic Gastric Reduction for Weight ManagementCompletedNCT01682733Phase 1
• Sleep Restriction and ObesityCompletedNCT01580761Not applicable
• A Psychological and Behavioral Intervention for Post-Bariatric PatientsCompletedNCT01453517Not applicable
• Effect of Self Regulation With Mindfulness Training on Body Mass Index and Cardiovascular Risk Markers in Obese AdultsCompletedNCT01375504Not applicable
• Influence of Male Hormones on Regional Fat MetabolismCompletedNCT01160328Phase 1
• Effects of Gastric Antral Botulinum Toxin Injections in Obese SubjectsCompletedNCT00976443Phase 1
• Fat Gain and Cardiovascular Disease MechanismsCompletedNCT00589498Phase 3
• Pharmacodynamic Effects of Sibutramine on Gastric Function in ObesityCompletedNCT00330525Phase 2
• FFA Metabolism in Different Types of Human ObesityWithdrawnNCT00068900