Mayo Clinic: Glioma trials

The registry lists 21 Glioma studies with Mayo Clinic as lead sponsor. 8 are open to participants now and 5 have results posted.

Early Phase 1 4Phase 1 4Phase 2 4Phase 4 2No phase 8(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Retifanlimab With or Without Difluoromethylornithine for the Treatment of Progressive High Grade GliomasRecruitingNCT07468136Phase 1/2
• A Study for Cerebral Open Flow MicroperfusionNot yet recruitingNCT07089758Not applicable
• A Digital Treatment Platform for the Delivery of Home-Based Sequential Therapy in Patients With Glioma, GHoST TrialRecruitingNCT07074756Not applicable
• Medication Combinations of Dasatinib, Quercetin, Fisetin, Temozolomide, LMP744, and Autologous TLPO Vaccine for the Treatment of Previously Treated Glioma With Residual DiseaseRecruitingNCT07025226Early Phase 1
• Mapping of Electrical Properties in the BrainRecruitingNCT06470711
• Intratumoral Extracellular Metabolic Impact of DFMO and AMXT 1501 in Patients With Diffuse or High Grade GliomaRecruitingNCT05717153Early Phase 1
• Preoperative Radiosurgery for the Treatment of High Grade Glioma, NeoGlioma TrialRecruitingNCT05030298Phase 1
• Feasibility of Intra- and Post-operative Microdialysis During Neurosurgery for Central Nervous System LesionsRecruitingNCT04047264Not applicable
• Perampanel for the Reduction of Seizure Frequency in Patients With High-grade Glioma and Focal EpilepsyTerminatedNCT04650204Phase 4Results posted
• 18F-DOPA-PET/MRI Scan in Imaging Elderly Patients With Newly Diagnosed Grade IV Malignant Glioma or Glioblastoma During Planning for a Short Course of Proton Beam Radiation TherapyCompletedNCT03778294Phase 2Results posted
• The Utility of 18F-DOPA-PET in the Treatment of Recurrent High-grade GliomaCompletedNCT03242824Phase 2Results posted
• 18F-DOPA-PET in Finding Tumors in Patients With Newly Diagnosed Gliomas Undergoing Radiation TherapyCompletedNCT01991977Phase 2Results posted
• Viral Therapy in Treating Patients With Recurrent Glioblastoma MultiformeCompletedNCT00390299Phase 1Results posted
• Comparing Telehealth and In-person Assessments in Glioma Patients Receiving Oral ChemotherapyCompletedNCT06625047Phase 4
• Advanced Development of Desorption Electrospray Ionization Mass Spectrometry for Intraoperative Molecular Diagnosis of Brain Cancer Using Pathology BiopsiesSuspendedNCT06387979
• Early Integration of Palliative Care Using the BEACON PROQOL in Patients With High Grade Glioma and Their CaregiversCompletedNCT04630379Not applicable
• Awake vs. Asleep Craniotomy for Non-eloquent GliomasCompletedNCT03621748Not applicable
• Wild-Type Reovirus in Combination With Sargramostim in Treating Younger Patients With High-Grade Relapsed or Refractory Brain TumorsCompletedNCT02444546Phase 1
• A Pilot Study Using 18F-DOPA PET-guided Radiotherapy in GliomasActive, not recruitingNCT02104310
• 18F-DOPA-PET in Planning Surgery in Patients with GliomasCompletedNCT02020720Early Phase 1
• Fluorine F 18 Fluorodopa-Labeled PET Scan in Planning Surgery and Radiation Therapy in Treating Patients With Newly Diagnosed High- or Low-Grade Malignant GliomaCompletedNCT01165632Early Phase 1