Mayo Clinic: Depressive Disorder trials

The registry lists 21 Depressive Disorder studies with Mayo Clinic as lead sponsor. 2 are open to participants now and 8 have results posted.

Phase 2 2Phase 3 1Phase 4 2No phase 16(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Enhancing Brain And Mental Health Through Breathing PracticeRecruitingNCT07369752Not applicable
• RNA Editing as a Biomarker of Antidepressant Response in Unipolar and Bipolar Depression (EDIT-ANDRE)RecruitingNCT07266545Phase 4
• Biomarkers in Repetitive Transcranial Magnetic Stimulation (rTMS) for Adolescent DepressionCompletedNCT03363919Not applicableResults posted
• The BIO-K Study: A Single-Arm, Open-Label, Biomarker Development Clinical Trial of Ketamine for Non-Psychotic Unipolar Major Depression and Bipolar I or II Depression.CompletedNCT03156504Phase 4Results posted
• Ketamine for Depression and Suicide RiskCompletedNCT02094898Phase 2Results posted
• Oral Ketamine in the Treatment of Depression and Anxiety in Patients With CancerTerminatedNCT01680172Phase 2Results posted
• Ketamine Anesthesia in Electroconvulsive TherapyCompletedNCT01367119Not applicableResults posted
• Study of Repetitive Transcranial Magnetic Stimulation (rTMS) as Adjuvant Treatment for DepressionTerminatedNCT01115699Not applicableResults posted
• Bipolar Depression Before and After Lamotrigine TreatmentCompletedNCT01042496Phase 3Results posted
• An Evaluation of Safety and Feasibility Using Repetitive Transcranial Magnetic Stimulation (rTMS) in Adolescents With DepressionCompletedNCT00587639Not applicableResults posted
• Stress Management and Resiliency Training for Depression vs Treatment as Usual in the Treatment of Major DepressionCompletedNCT04388748Not applicable
• Augmented Human Intelligence in Major Depressive DisorderCompletedNCT04355650Not applicable
• Transcranial Direct Current Stimulation (tDCS) in Children and Adolescents With Epilepsy and DepressionWithdrawnNCT03368469Not applicable
• Stress Management and Resiliency Training (SMART) Integrated Into Treatment of Major DepressionCompletedNCT03275961Not applicable
• Clinical Impact of the Antidepressant Pharmacogenomic Algorithm in an Outpatient Therapy-based Clinical SettingCompletedNCT02479464Not applicable
• Microbiome of Depression & Treatment Response to CitalopramCompletedNCT02330068
• Glutamate Probes in Adolescent DepressionCompletedNCT02307617
• A PK/PD Genetic Variation Treatment Algorithm Versus Treatment As Usual for Adolescent Management Of DepressionCompletedNCT02286440Not applicable
• A Pharmacokinetic/Pharmacodynamic Genetic Variation Treatment Algorithm Versus Treatment As Usual for Management Of DepressionCompletedNCT02189057Not applicable
• Cortical Excitability and Inhibition in MDDCompletedNCT01718730
• Cognitive Behavioral Therapy, Self-Efficacy, and Depression in Persons With Chronic PainCompletedNCT01055665