Mayo Clinic: Melanoma trials

The registry lists 43 Melanoma studies with Mayo Clinic as lead sponsor. 6 are open to participants now and 5 have results posted.

Early Phase 1 7Phase 1 17Phase 2 9Phase 4 1No phase 12(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Studying Quality of Life Inclusive of Mental Health and Cognitive Behavioral Therapy for Cancer Distress for the Improvement of Quality of Life in Stage III-IV Melanoma PatientsRecruitingNCT07379138Not applicable
• The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding AreasRecruitingNCT07285044Phase 2
• Digital Remote Monitoring of Immune Checkpoint Inhibitor Therapy Induced Toxicity Using the Vigilant AppRecruitingNCT06675643
• Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) ProgramRecruitingNCT06265285Phase 2
• Evaluation of Anti-PD-1 Therapy by Monitoring T Cell Responses in Melanoma, Lung and Other Cancer TypesRecruitingNCT06075524
• Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid TumorsRecruitingNCT05269381Phase 1/2
• Dendritic Cell Therapy With Pembrolizumab for Metastatic or Unresectable MelanomaTerminatedNCT03325101Phase 1/2Results posted
• Imiquimod and Pembrolizumab in Treating Patients With Stage IIIB-IV MelanomaCompletedNCT03276832Early Phase 1Results posted
• Neoadjuvant Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) in Cutaneous Stage L-lll MelanomaCompletedNCT02451488Phase 4Results posted
• Individualized Temozolomide in Treating Patients With Stage IV Melanoma That Cannot Be Removed By SurgeryCompletedNCT01328535Phase 2Results posted
• Paclitaxel and Carboplatin or Temozolomide in Treating Patients With Stage IV MelanomaTerminatedNCT00568451Phase 2Results posted
• Associations Between Chemotherapy-Induced Nausea in Patients With Genitourinary, Sarcoma or Melanoma Cancers and Changes in Gut Microbiome: Potential for Precision TherapeuticsTerminatedNCT05819827
• Pharmacokinetic Profiling of Pembrolizumab and Nivolumab in Patients With Melanoma and/or Non-Small Cell Lung CancerCompletedNCT05740501
• Aerosolized Sargramostim Added to Immunotherapy for the Treatment of Patients With Metastatic Melanoma to the LungWithdrawnNCT05717140Phase 1
• CA-4948 in Combination With Pembrolizumab and Stereotactic Radiosurgery to Improve Treatment of Melanoma Brain MetastasesSuspendedNCT05669352Phase 1/2
• Intra-Lymphatic STI-3031 Using the Sofusa DoseConnect Device for Treatment of In-Transit Melanoma, The Sofusa-2 StudyTerminatedNCT05393713Phase 1
• E6201 and Dabrafenib for the Treatment of Central Nervous System Metastases From BRAF V600 Mutated Metastatic MelanomaTerminatedNCT05388877Phase 1
• Education for Prevention of Melanoma in Hispanic PopulationsTerminatedNCT05388851Phase 2
• Ipilimumab and Nivolumab for the Treatment of Stage III-IV Unresectable Metastatic MelanomaTerminatedNCT04967196Phase 1
• Radiation Therapy, Plasma Exchange, and Immunotherapy (Pembrolizumab or Nivolumab) for the Treatment of MelanomaCompletedNCT04581382Early Phase 1
• Pharmacogenomics Testing in the Optimal Use of Supportive Care Medications in Stage III-IV CancerCompletedNCT04067960Early Phase 1
• Sonidegib and Pembrolizumab in Treating Patients With Advanced Solid TumorsActive, not recruitingNCT04007744Phase 1
• Modified Virus VSV-IFNbetaTYRP1 in Treating Patients With Stage III-IV MelanomaTerminatedNCT03865212Phase 1
• Preventing Lymphedema in Axillary Lymph Node DissectionTerminatedNCT03428581Not applicable
• Two Cancers, One Gene. Why Some People in Families Develop Melanoma or Pancreas Cancer, While Still Others Never Develop Cancer.CompletedNCT03174574
• Pembrolizumab and Ibrutinib in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by SurgeryCompletedNCT03021460Phase 1
• Immune Predictors of Response to Pembrolizumab Therapy in Stage IV Melanoma PatientsTerminatedNCT02744209
• TLR8 Agonist VTX-2337 and Cyclophosphamide in Treating Patients With Metastatic, Persistent, Recurrent, or Progressive Solid TumorsTerminatedNCT02650635Phase 1
• MART-1 Antigen With or Without TLR4 Agonist GLA-SE in Treating Patients With Stage II-IV Melanoma That Has Been Removed by SurgeryCompletedNCT02320305Early Phase 1
• Nab-Paclitaxel and Bevacizumab in Treating Patients With Unresectable Stage IV Melanoma or Gynecological CancersCompletedNCT02020707Phase 1
• Second Echelon Node Study With Methylene BlueCompletedNCT01823172Not applicable
• Aldesleukin Imaging in Viewing Tumor Growth in Patients With Stage IV Melanoma Receiving Ipilimumab or Pembrolizumab TherapyCompletedNCT01789827Early Phase 1
• Immune Responses in Prostate, Lung, Melanoma and Breast Cancer Patients Following Stereotactic Body Radiotherapy (SBRT), Intensity Modulated Radiotherapy (IMRT) or BrachytherapyCompletedNCT01777802
• Vaccine Therapy and Resiquimod in Treating Patients With Stage II-IV Melanoma That Has Been Removed By SurgeryCompletedNCT01748747Early Phase 1
• Minimally Invasive Groin Dissection for MelanomaCompletedNCT01500304Not applicable
• Collecting Blood and Tissue Samples From Family Members of Patients With Pancreatic Diseases, Pancreatic Cancer, and MelanomaActive, not recruitingNCT00835133
• Monoclonal Antibody Therapy in Treating Patients With Stage IV MelanomaCompletedNCT00658892Phase 1
• Everolimus and Vatalanib in Treating Patients With Advanced Solid TumorsCompletedNCT00655655Phase 1
• ABT-510 in Treating Patients With Metastatic MelanomaCompletedNCT00602199Phase 2
• Radiofrequency Therapy-Induced Endogenous Heat-Shock Proteins With or Without Radiofrequency Ablation or Cryotherapy in Treating Patients With Stage IV MelanomaCompletedNCT00568763Phase 1
• Vaccine Therapy and Resiquimod in Treating Patients With Stage II, Stage III, or Stage IV Melanoma That Has Been Completely Removed by SurgeryCompletedNCT00470379Early Phase 1
• Vaccine Therapy and GM-CSF With or Without Low-Dose Aldesleukin in Treating Patients With Stage II, Stage III, or Stage IV MelanomaCompletedNCT00470015Phase 1
• Flavopiridol Plus Cisplatin or Carboplatin in Treating Patients With Advanced Solid TumorsCompletedNCT00003690Phase 1