SupplementDrug
Vitamin B 12 clinical trials
Also written Vitamin B12.
Keep track of what changes. Save the Vitamin B 12 studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Name
Other names
Studies by the year they started
79 studies that test it; most in 2008 (6)
| Year | Studies |
|---|---|
| 1993 | 1 |
| 1999 | 1 |
| 2001 | 1 |
| 2004 | 5 |
| 2005 | 4 |
| 2006 | 5 |
| 2007 | 3 |
| 2008 | 6 |
| 2009 | 3 |
| 2010 | 4 |
| 2011 | 3 |
| 2012 | 2 |
| 2013 | 2 |
| 2014 | 4 |
| 2015 | 2 |
| 2016 | 2 |
| 2017 | 4 |
| 2018 | 4 |
| 2019 | 4 |
| 2020 | 2 |
| 2021 | 3 |
| 2022 | 1 |
| 2023 | 1 |
| 2024 | 4 |
| 2025 | 6 |
| 2026 | 2 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 7 · Other 72
University of Aarhus (4) · Centre For International Health (2) · Brigham and Women's Hospital (2) · Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh (2) · Acrotech Biopharma Inc. (2) · Chinese University of Hong Kong (2) · Northwell Health (2) · Francisco Javier Martínez Noguera (2)
Often tested with
Tested in the same studies.
Folic Acid (24) · Pyridoxine (12) · Vitamin B 6 (8) · Pralatrexate (3) · Cisplatin (2) · Levomefolic acid (2) · Iron (2) · Omega-3 fatty acid (2)
Studies
Open first, then newest update. How each study uses Vitamin B 12 is read from its arms, and is right about nine times in ten.
Testing it · 79
- Comparative Study of Combination Treatment of Bionerv E+ Versus Vitamin B Complex in Treatment of Diabetic Polyneuropathy in Type 2 Diabetic Patients and Its Effect on Wound HealingRecruitingNot applicableBREGO Life SciencesNCT07877948Written as Alpha-Lipoic Acid, Vitamin B1, Vitamin B6, Vitamin B12, Vitamin E
- Efficiency of a Composite Personalised Care on Functional Outcome in Early PsychosisRecruitingPhase 3Centre Hospitalier St AnneNCT05796401Written as Personalized neuroprotective strategies : Vitamin B12, folinic acid, Omega 3, NAC
- Microbiological and Clinical Effects of Pre- and Probiotics in Non-Surgical Periodontal TherapyRecruitingNot applicableUniversity Hospital HeidelbergNCT07443410Written as Vitamin B12 drops (natural elements)
- Effects of Vitamin B12 and Natural Orange Extract, and Their Combination on Physical and Mental PerformanceEnrolling by invitationNot applicableFrancisco Javier Martínez NogueraNCT07341789Written as Vitamin B 12
- ICOPE INTENSE-K Pilot StudyRecruitingNot applicableUniversity Hospital, ToulouseNCT07048860Written as Vitamin B12
- This Randomized, Clinical Trial Evaluates the Efficacy of Oral Versus Sublingual Vitamin B12 Supplementation in Correcting Early-onset Vitamin B12 Deficiency in Adult Patients Using Proton Pump Inhibitors (PPIs). The Primary Outcome is the Change in Serum Vitamin B12 Levels Over a 6-weekNot yet recruitingPhase 3Tanta UniversityNCT06966856Written as Cyanocobalamin 1000 Mcg Oral Tablet
- Study on the Improvement of Microcirculation in Patients With Sepsis by Vitamin B6, Vitamin B12 and Vitamin CRecruitingNot applicableFan ZengNCT06749756Written as vitamin B6+ Vitamin B12 +vitamin C
- Pilot Study of Open Label Homocysteine Management Therapy in Levodopa-treated Parkinson's DiseaseRecruitingNot applicableOregon Health and Science UniversityNCT06772220Written as Vitamin B12
- Effect of a New Formulation of Vitamin B12 on Physical and MentalRecruitingNot applicableFrancisco Javier Martínez NogueraNCT06639789Written as Vitamin B12 (B12)
- Early Infant Micronutrition and DevelopmentRecruitingPhase 2/3Sykehuset Innlandet HFNCT05005897Written as Cyanocobalamin
- Effect of Preoperative Intervention With Folic Acid and Vitamin B12 on Postoperative Neurobehavioral Changes in ChildrenRecruitingNot applicableShanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong UniversityNCT04456985Written as Folic acid and vitamin B12
- Pemetrexed, Cisplatin, and Vitamin B12 in Treating Patients With Mesothelioma of the Chest That Cannot Be Removed by SurgeryCompletedPhase 2Centre Oscar LambretNCT00541073Written as vitamin B12
- Vitamin B12 Absorption StudyCompletedPhase 4RDC Clinical Pty LtdNCT07665671Written as Ampli-B
- A Study to See if a Combination of Vitamins That is Injected Into a Muscle is as Good and Safe as a Vitamin That is Taken by MouthCompletedPhase 4Medice Arzneimittel Pütter GmbH & Co KGNCT07029698Written as Vitamin B12, Vitamin B6, Folic acid
- Vitamin B12 Supplementation During Pregnancy on Cognitive DevelopmentActive, not recruitingPhase 2/3Centre For International HealthNCT03071666Written as cobalamin
- Effectiveness of Vitamin b12 Versus Kenalog on Traumatic Ulcer Associated With Orthodontic TreatmentCompletedNot applicableHawraa Ali AbdullahNCT07004465Written as cyanocobalamin
- GLP-1 Therapy: The Role of IL-6 Signaling and Adipose Tissue Remodeling in Metabolic ResponseCompletedPhase 4The University of Texas Health Science Center, HoustonNCT04387201Written as Cyanocobalamin
- Vitamin B12 for Aromatase Inhibitors Associated Musculoskeletal Symptoms in Breast CancerWithdrawnNot applicableCase Comprehensive Cancer CenterNCT04205786Written as Vitamin B12
- Assessing the Efficacy of Different Carrier Systems in Oral Vitamin B12 SupplementationCompletedNot applicableLiaquat University of Medical & Health SciencesNCT06376591Written as Vit B12
- Vitamin B12, Neurodevelopment and Growth in NepalStatus unknownPhase 2/3Centre For International HealthNCT02272842Written as Vitamin B12
See all 79 studies that test Vitamin B 12 →
Given in every arm · 36 — Vitamin B 12 is usual care beside what is tested
- Pembrolizumab Plus Bevacizumab and Chemotherapy for Non-Squamous NSCLC PatientsActive, not recruitingPhase 2Shanghai Chest HospitalNCT05751187Written as Vitamin B12 1000 μg
- Improving HbA1c Levels by Methylcobalamin Vitamin in Diabetic VolunteersCompletedNot applicableAl-Balqa Applied UniversityNCT06241638Written as Vitamin B12 0.5 MG/ACTUAT
- Intrathecal Pemetrexed for Leptomeningeal MetastasisCompletedPhase 1/2The First Hospital of Jilin UniversityNCT05289908Written as Vitamin B12
- Study of Pemetrexed+Platinum Chemotherapy With or Without Cosibelimab in First Line Metastatic Non-squamous NSCLCTerminatedPhase 3Checkpoint Therapeutics, Inc.NCT04786964Written as Vitamin B12 1000 μg
- Study of Pemetrexed+Platinum Chemotherapy With or Without Pembrolizumab (MK-3475) in Participants With First Line Metastatic Nonsquamous Non-small Cell Lung Cancer (MK-3475-189/KEYNOTE-189)CompletedPhase 3Merck Sharp & Dohme LLCNCT02578680Written as Vitamin B12 1000 μg
- Study of Pemetrexed+Platinum Chemotherapy With or Without Pembrolizumab (MK-3475) in Participants With First Line Metastatic Nonsquamous Non-small Cell Lung Cancer (MK-3475-189/KEYNOTE-189)-Japan Extension StudyCompletedPhase 3Merck Sharp & Dohme LLCNCT03950674Written as Vitamin B12 1000 μg
- KEAPSAKE: A Study of Telaglenastat (CB-839) With Standard-of-Care Chemoimmunotherapy in 1L KEAP1/NRF2-Mutated, Nonsquamous NSCLCTerminatedPhase 2Calithera Biosciences, IncNCT04265534Written as Vitamin B12 1000 μg
- Study of Pembrolizumab With Pemetrexed and Oxaliplatin in Chemo-Refractory Metastatic Colorectal Cancer PatientsStatus unknownPhase 1NSABP Foundation IncNCT03626922Written as Vitamin B-12
- Study of Pralatrexate to Treat Participants With Relapsed or Refractory B-cell Non-Hodgkin's LymphomaCompletedPhase 2Spectrum Pharmaceuticals, IncNCT00998946Written as Vitamin B12
- Study of Pralatrexate vs. Erlotinib for Non-Small Cell Lung Cancer After at Least 1 Prior Platinum-based TreatmentCompletedPhase 2Spectrum Pharmaceuticals, IncNCT00606502Written as Vitamin B12
- International ALLIANCE Study of Therapies to Prevent Progression of COVID-19Status unknownPhase 2National Institute of Integrative Medicine, AustraliaNCT04395768Written as Vitamin B12
- The Benefit of Add On DLBS1033 for Ischemic Stroke PatientStatus unknownPhase 2/3Duta Wacana Christian UniversityNCT04425590Written as Vit B12
- Study of Pralatrexate in Female Patients With Previously-treated Breast CancerCompletedPhase 2Acrotech Biopharma Inc.NCT01118624Written as Vitamin B12
- Pralatrexate and Bexarotene in Patients With Relapsed or Refractory Cutaneous T-cell LymphomaCompletedPhase 1Acrotech Biopharma Inc.NCT01134341Written as Vitamin B12
- Comparing Efficacy and Safety of CinnaGen Beta Erythropoietin (CinnaPoietin®) Versus Eprex® on the Treatment of Anemia in ESRD Hemodialysis PatientsCompletedPhase 3CinnagenNCT03408639Written as Vitamin B12 Injection
- Study of Pralatrexate to Treat Advanced or Metastatic Relapsed Transitional Cell Carcinoma of the Urinary BladderCompletedPhase 2Acrotech Biopharma Inc.NCT00722553Written as Vitamin B12
- Sirolimus and Pemetrexed to Treat Non-Small Cell Lung CancerTerminatedPhase 1/2National Cancer Institute (NCI)NCT00923273Written as Vitamin B12
- Phase II Study of Folotyn With Leucovorin to Prevent/Reduce Mucositis in Patients With Hematological MalignanciesCompletedPhase 2Acrotech Biopharma Inc.NCT02106650Written as Vitamin B12
- A Single Arm Study Evaluating the Efficacy and Safety of Pralatrexate in Subjects With Relapsed or Refractory PTCLCompletedPhase 3Mundipharma (China) Pharmaceutical Co. LtdNCT03349333Written as Vitamin B12 and folic acid
- A Study of Pemetrexed/Cisplatin as Pre-operative Treatment of Early Stage Nonsquamous Non-Small Cell Lung CancerCompletedPhase 2Eli Lilly and CompanyNCT01165021Written as Vitamin B12
Showing 20 of 36.
As the comparator · 3 — what is tested is compared with Vitamin B 12
- Effect of Methylcobalamin and Cyanocobalamin Consumption on Vitamin B12 Nutritional StatusRecruitingNot applicableFundació EurecatNCT05785585Written as Cyanocobalamin group
- Testing the Use of Combination Immunotherapy Treatment (N-803 [ALT-803] Plus Pembrolizumab) Against the Usual Treatment for Advanced Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)Active, not recruitingPhase 2/3SWOG Cancer Research NetworkNCT05096663Written as Cobalamin
- Vitamin B12 Dose Escalation Trial in PregnancyActive, not recruitingPhase 1George Washington UniversityNCT05426395Written as Vitamin B12 2.6 µg
Codes
What other systems call Vitamin B 12 · ClinicalTrials.gg INT008414
- MeSH (NLM) D014805Vitamin B 12Confirmed ClinicalTrials.gov, NLM
- UNII (FDA) 8406EY2OQACOBALAMINConfirmed FDA, NLM
- RxNorm 42604One source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D014805 | Vitamin B 12 | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | 8406EY2OQA | COBALAMIN | Confirmed FDA, NLM |
| RxNorm | 42604 | — | One source FDA |
Also registered as cyanocobalamin (UNII P6YC3EG204 · RxNorm 11248).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.