Vitamin B 12 Deficiency clinical trials
The registry lists 73 studies for Vitamin B 12 Deficiency across more than 10 countries. 8 are recruiting or about to start. 43 of them are mainly about Vitamin B 12 Deficiency (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-02.
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Status
Who runs them
Haukeland University Hospital (3) · Nutrition Institute, Slovenia (3) · University of Aarhus (3) · University of California, Davis (3) · USDA, Western Human Nutrition Research Center (2) · Northwell Health (2) · Liaquat University of Medical & Health Sciences (2) · University of British Columbia (2)
What is being tested here
Drugs under test in Vitamin B 12 Deficiency studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Vitamin B 12 | 1 | 2 | 13 |
| Hydroxocobalamin | 0 | 0 | 4 |
| Mecobalamin | 0 | 0 | 3 |
| Folic Acid | 0 | 0 | 2 |
| Vitamin B 6 | 0 | 0 | 1 |
| Pyridoxine | 0 | 0 | 1 |
| Levomefolate calcium | 0 | 0 | 1 |
| B12 | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 2
- Dec 2026Challenges in Achieving Adequate Dietary Status of Women · Nutrition Institute, Slovenia
- Dec 2026Diet Quality of Pregnant Women With a Strict Plant-based Diet Versus an Omnivorous Diet · Maastricht University Medical Center
Who these studies take
Of the 2 Vitamin B 12 Deficiency studies recruiting now, 0 (0%) set no upper age limit and 2 (100%) stop at 75 or younger. 2 (100%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 1 (50%) | 1 (50%) |
| 30 | 1 (50%) | 1 (50%) |
| 40 | 1 (50%) | 1 (50%) |
| 50 | 0 (0%) | 0 (0%) |
| 65 | 0 (0%) | 0 (0%) |
| 75 | 0 (0%) | 0 (0%) |
| 85 | 0 (0%) | 0 (0%) |
Across all 73 studies, recruiting or not: 58% stop at 75 or younger and 45% at 65; 23% take children; 23% are for women only and 1% for men only; 52% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Vitamin B 12 Deficiency studies take
Of 19 interventional studies with no phase under Vitamin B 12 Deficiency, half reached primary completion within 7 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 7 mo4–38 · 19 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 73. Browse all 73 → or search them.
- THE B-BABIES STUDY: An Observational Study of Group B Vitamins in Preterm InfantsNot yet recruitingNCT071639621 country
- Effectiveness of a Modified Cost-Effective Dietary Plan in Promoting Weight Loss and Preservation of Lean Body Mass in Patients After Bariatric SurgeryNot yet recruitingNCT07111767Not applicable1 country
- Neurological Recovery Following NOS-SACDRecruitingNCT057149171 country
- Challenges in Achieving Adequate Dietary Status of WomenEnrolling by invitationNCT067458171 country
- Hydroponic Fortification and Dietary App Effect on Nutrients Level (Harvest)Enrolling by invitationNCT05740462Not applicable1 country
- Vitamin B12 Status and Its Impact on Chronic Haemodialysis PatientNot yet recruitingNCT06441721
- Diet Quality of Pregnant Women With a Strict Plant-based Diet Versus an Omnivorous DietNot yet recruitingNCT06046703
- Early Infant Micronutrition and DevelopmentRecruitingNCT05005897Phase 2/31 country
- Dietary Challenges in the Population of Nursing Homes' ResidentsCompletedNCT053896181 country
- A Study to See if a Combination of Vitamins That is Injected Into a Muscle is as Good and Safe as a Vitamin That is Taken by MouthCompletedNCT07029698Phase 41 country
- Oral Versus Intravenous Vitamin B12 Replacement in Hemodialysis PatientsCompletedNCT07781020Not applicable1 country
- Effectiveness of Fortification With Folic Acid and Vitamin B12 Among Teenage GirlsCompletedNCT06100146Not applicable1 country
- Vitamin B12 Supplementation During Pregnancy on Cognitive DevelopmentActive, not recruitingNCT03071666Phase 2/31 country
- Vitamin B12 Dose Escalation Trial in PregnancyActive, not recruitingNCT05426395Phase 11 country
- Pre- and Post-Treatment Investigation of B12 and Folic Acid (Folate) Levels in Patients Receiving Antiepileptic (Anticonvulsant) Treatment for Fibromyalgia: Retrospective StudyCompletedNCT070133051 country
- Oral Sucrosomial® Vitamin B12 in the Management of B12 Deficiency Among Metformin-Treated Type 2 Diabetes PatientsCompletedNCT06983223Not applicable1 country
- Pre- and Post-Treatment Investigation of B12 and Folic Acid (Folate) Levels in Patients Receiving Antiepileptic (Anticonvulsant) Treatment for Neuropathic PainCompletedNCT070133181 country
- Baby Detect : Genomic Newborn ScreeningCompletedNCT056874741 country
- Preoperative Anaemia prevaLence In surgiCal patiEntsCompletedNCT039782601 country
- Using Iodized Salt to Improve Serum Folate, B12 and Iron LevelsCompletedNCT069046122 countries
- Cobalamin Supply and Metabolism in Healthy Children From Birth to the Age of 12 Months and in Their Mothers (Cbl_Neo)CompletedNCT053158432 countries
- Acceptability and Nutritional Impact of Double-fortified Salt Containing Iodine and Folic AcidCompletedNCT06223854Not applicable1 country
- An Exploratory Investigation of a B12 Vitamin to Increase Energy and FocusCompletedNCT05517005Not applicable1 country
- Heart Failure With Reduced Ejection Fraction: Adjuvant Therapy With Neurostimulation and Chlorella Pyrenoidosa (HD-tDCS)Active, not recruitingNCT06528366Not applicable1 country
- Assessing the Efficacy of Different Carrier Systems in Oral Vitamin B12 SupplementationCompletedNCT06376591Not applicable1 country
- Effect of Household Use of Multiple Micronutrient-fortified Bouillon on Micronutrient Status Among Women and Children in Two Districts in the Northern Region of GhanaCompletedNCT05178407Not applicable1 country
- Egg Intervention During Pregnancy in IndonesiaActive, not recruitingNCT04694235Not applicable1 country
- Quadruple Fortified Salt Trial in IndiaActive, not recruitingNCT03853304Not applicable1 country
- Periconceptional Surveillance in IndiaActive, not recruitingNCT040483301 country
- Relationship Between Vitamin D and Vitamin B12 Levels and Neuropathic Pain in LipedemaActive, not recruitingNCT063380591 country
- Effect of Daily Consumption of Vitamin B12 Fortified Yoghurt on Vitamin B12 Status in Older AdultsCompletedNCT05993962Not applicable1 country
- ETOL-Elderly Study of the Efficiency of the Innovative Food Supplement in Elderly AdultsCompletedNCT05661006Not applicable1 country
- Dried Purple Laver (Nori) as a Food Source of Vitamin B12 in VegetariansCompletedNCT05614960Not applicable1 country
- A Comparison of Two Different Doses of Maternal B12 Supplementation in Improving Infant B12 Deficiency and NeurodevelopmentCompletedNCT04083560Not applicable2 countries
- Nutritional Status and Bouillon Use in Northern GhanaCompletedNCT046327711 country
- Natural Versus Synthetic Vitamin B Complexes in HumanCompletedNCT03444155Not applicable1 country
- Anemia in Older AdultsCompletedNCT04820465
- Adults Nutrition as a Protective or Health-risk FactorCompletedNCT032848401 country
- Transdermal Iontophoresis of Vitamin B12 Under Three Different Skin PreparationsCompletedNCT04027959Not applicable1 country
- Vitamin Deficiencies and Suppletion in Morbid ObesityCompletedNCT02270749Phase 41 country
- Cobalamin Deficiency - Diagnosis and TherapyCompletedNCT042437071 country
- Maternal B12 Supplementation to Improve Infant B12 Deficiency and NeurodevelopmentStatus unknownNCT03783104Not applicable2 countries
- Effects of Vitamin B12 Treatment in SingersCompletedNCT03437824Early Phase 11 country
- The Impact of Vitamin B12 Deficiency on Infant Gut MicrobiotaCompletedNCT033655831 country
- The Role of Methycobalamin in Early Dementia Patients With Vitamin B12 Deficiency and Hyperhomocysteinaemia.CompletedNCT00165711Phase 41 country
- Supplementation of Critical Nutrients in a Plant-based DietCompletedNCT035425911 country
- Cracking the Egg Potential: Improving Young Child Nutrition in EcuadorCompletedNCT02446873Not applicable1 country
- The Vitamin B Status in Type 2 Diabetes (VITA) StudyCompletedNCT03447275
- Effect of Toothpaste Fortified With Cyanocobalamin on Vitamin B12 StatusCompletedNCT02679833Not applicable1 country
- Homocysteine After Laparoscopic Roux-enY Gastric BypassCompletedNCT034895381 country