Oral Ulcer clinical trials
The registry lists 54 studies for Oral Ulcer across more than 10 countries. 11 are recruiting or about to start. 21 of them are mainly about Oral Ulcer (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-04.
Get an email when these change. Save the Oral Ulcer studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
See an example email
Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Who runs them
Cairo University (3) · Amgen (3) · i+Med S.Coop. (2) · Dow University of Health Sciences (2) · Yuzuncu Yıl University (1) · National Institute of Dental and Craniofacial Research (NIDCR) (1) · Swedish Orphan Biovitrum (1) · Hillel Yaffe Medical Center (1)
What is being tested here
Drugs under test in Oral Ulcer studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 7
- Nov 2026A Study of Phenytoin Mucoadhesive Film for Oral Ulcers in Healthy Volunteers · Misr University for Science and Technology
- Dec 2026Lenalidomide in the Treatment of Mucosal Behçet's Syndrome · Peking Union Medical College Hospital
- Jan 2027Comparing the Extent to Which Apremilast is Made Available in the Body After Administration as an Extended-release or Immediate-release Formulation · Amgen
- Mar 2027Phase II Single Arm Open Label Study Evaluating the Feasibility and Safety of Photobiomodulation as an Adjunct to Standard Supportive Care for Chemotherapy Induced Oral Mucositis in Pediatric Patients With Hematolymphoid Malignancies · Tata Memorial Hospital
- Apr 2027Evaluation of Topical Rebamipide Versus Topical Betamethasone for Treatment of Oral Aphthous Ulcers · Cairo University
- Apr 2027Observational Study of OROSEDAL in Sore Throat and Minor Oral Lesions · Laboratoires Elerte
- Jul 2027The Preventive and Therapeutic Effects of Spirulina Preparations on Ulcers of Oral Mucosa · The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Who these studies take
Of the 6 Oral Ulcer studies recruiting now, 1 (17%) set no upper age limit and 4 (67%) stop at 75 or younger. 3 (50%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (50%) | 3 (50%) |
| 18 | 5 (83%) | 5 (83%) |
| 30 | 4 (67%) | 4 (67%) |
| 40 | 4 (67%) | 4 (67%) |
| 50 | 4 (67%) | 4 (67%) |
| 65 | 4 (67%) | 4 (67%) |
| 75 | 2 (33%) | 2 (33%) |
| 85 | 2 (33%) | 2 (33%) |
Across all 54 studies, recruiting or not: 50% stop at 75 or younger and 43% at 65; 37% take children; 4% are for women only and 0% for men only; 31% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Oral Ulcer studies take
Of 16 interventional studies with no phase under Oral Ulcer, half reached primary completion within 11 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 11 mo6–29 · 16 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered2
Studies
Recruiting first, then most recently updated. Showing 50 of 54. Browse all 54 → or search them.
- A Study of Apremilast in Children With Oral Ulcers Associated With Behçet's Disease or Juvenile Psoriatic ArthritisRecruitingNCT05767047Phase 34 countries
- Comparing the Extent to Which Apremilast is Made Available in the Body After Administration as an Extended-release or Immediate-release FormulationNot yet recruitingNCT07908641Phase 1
- A Study of Phenytoin Mucoadhesive Film for Oral Ulcers in Healthy VolunteersNot yet recruitingNCT07890428Phase 11 country
- Evaluation of Topical Rebamipide Versus Topical Betamethasone for Treatment of Oral Aphthous UlcersRecruitingNCT06084624Phase 21 country
- Apremilast Pediatric Study in Children With Active Oral Ulcers Associated With Behçet's DiseaseRecruitingNCT04528082Phase 38 countries
- The Preventive and Therapeutic Effects of Spirulina Preparations on Ulcers of Oral MucosaRecruitingNCT07723612Not applicable1 country
- Lenalidomide in the Treatment of Mucosal Behçet's SyndromeRecruitingNCT05449548Not applicable1 country
- Observational Study of OROSEDAL in Sore Throat and Minor Oral LesionsRecruitingNCT076203531 country
- Phase II Single Arm Open Label Study Evaluating the Feasibility and Safety of Photobiomodulation as an Adjunct to Standard Supportive Care for Chemotherapy Induced Oral Mucositis in Pediatric Patients With Hematolymphoid MalignanciesNot yet recruitingNCT07605234Not applicable
- Mucoadhesive Film With/without Acmella Oleracea & Triamcinolone Acetonide for Aphthous UlcersNot yet recruitingNCT06622213Phase 2
- Study for the Prevention of Oral Mucositis (SPOM)Enrolling by invitationNCT05338398Phase 1/21 country
- Comparison of Hyaluronic Acid and Chlorhexidine Gels for Traumatic Oral Ulcers During Fixed Orthodontic TreatmentCompletedNCT07709455Not applicable1 country
- Efficacy of 5% Chitosan Nanoparticle Paste in the Treatment of Recurrent Aphthous StomatitisCompletedNCT07702474Phase 2
- A Study on Sumac Mouth Rinse for Treating Recurrent Aphthous StomatitisCompletedNCT07229469Not applicable1 country
- Effectiveness of Vitamin b12 Versus Kenalog on Traumatic Ulcer Associated With Orthodontic TreatmentCompletedNCT07004465Not applicable1 country
- Non-Thermal Plasma vs. Low-Level Laser Therapy for Recurrent Oral UlcersCompletedNCT07322666Not applicable1 country
- Pilot Clinical Study Testing Tiger Milk Mushroom Gel (Lignosus Rhinocerus TM02®) for Treating Mouth UlcersCompletedNCT06969495Not applicable1 country
- Post-marketing Study for the Evaluation of Profilm Mouth SoresCompletedNCT06741280Not applicable1 country
- Post-marketing Study for the Evaluation of Profilm Cold SoresCompletedNCT06734728Not applicable1 country
- Ustekinumab (Anti-IL-12/23p40 Monoclonal Antibody) in Patients With Leukocyte Adhesion Deficiency Type 1 (LAD1) Who Have Inflammatory PathologyCompletedNCT03366142Phase 1/21 country
- Clinical Efficiency of Natural Herbal Based Gel.CompletedNCT06490289Not applicable1 country
- Comparison of the Effects of Oral Ulceration Healing in Patients Wearing a Removable DentureCompletedNCT06531720Not applicable1 country
- Treatment of Aphtous Ulcers With Photodynamic TherapyCompletedNCT06379438Not applicable1 country
- Implementation of a Minor Ailment Service in Community Pharmacy PracticeCompletedNCT05247333Not applicable1 country
- ROMAN: Phase 3 Trial Investigating the Effects of GC4419 on Radiation Induced Oral Mucositis in Head/Neck Cancer PatientsCompletedNCT03689712Phase 33 countries
- Effectiveness of a Curcumin Mouthwash in Preventing Traumatic Ulcers in Patients With Fixed Orthodontic AppliancesCompletedNCT05147376Early Phase 11 country
- Combination of Diclofenac Potassium and Propolis in the Therapy of Oral AphthosisCompletedNCT05413096Early Phase 11 country
- Clonidine HCl MBT vs. Placebo to Prevent Chemoradiotherapy-Induced Severe Oral Mucositis in Oropharyngeal Cancer.TerminatedNCT04648020Phase 2/35 countries
- The Efficacy of Topical Mesalazine Sustained-Release Tablets in Crohn's Disease Patients With Oral UlcerWithdrawnNCT02769494Phase 31 country
- Miracle Mouthwash Plus Hydrocortisone vs Prednisolone Mouth Rinse for Mouth Sores Caused by EverolimusCompletedNCT02229136Phase 21 country
- Dose-ranging Study of Dentoxol® Mouthrinse for Managing Oral Symptoms in People With Epidermolysis Bullosa.Status unknownNCT05288478Phase 21 country
- Therapeutic Effect of Folic Acid in Healing of Oral UlcersStatus unknownNCT04989049Early Phase 1
- Uses of Tacrolimus in Behcet DiseaseCompletedNCT05032248Not applicable1 country
- Using Tea-based Mouthwash Relieve Stomatitis and Oral UlcersStatus unknownNCT05010928Phase 21 country
- Clinical Evaluation of the OncAlert RAPID in Subjects Presenting for Evaluation and/or Initial Biopsy; Impact on Decision-MakingCompletedNCT032398341 country
- Hyaluronic Acid in Counteracting Aphthous StomatitisCompletedNCT048844641 country
- Basil Extract (Ocimum Basilicum) in the Management of Recurrent Aphthous StomatitisStatus unknownNCT04710888Phase 21 country
- PRF in Management of Chronic Multiple Oral UlcersCompletedNCT03878771Phase 11 country
- Probiotic Lozenges for Treatment of Recurrent Aphthous StomatitisCompletedNCT04383236Not applicable
- Use of Topical NSAID to Reduce Pain in Oral Lichen Planus and Oral Lichenoid Lesions.CompletedNCT03509675Phase 2/31 country
- Diode Laser Versus Topical Corticosteroids in Management of Oral Ulcers in Behcet's DiseaseStatus unknownNCT03771768Not applicable
- Tocilizumab for the Treatment of Behcet's SyndromeTerminatedNCT01693653Phase 21 country
- Aloe Vera and Chlorhexidine Against Traumatic Oral UlcersCompletedNCT03633292Phase 41 country
- Oral Ulcer Prevalence: Hospital-based Cross-sectional StudyCompletedNCT03167632
- A Randomized Controlled Trial Evaluating the Effectiveness of a Salvia-based Mouthwash in Palliative CareCompletedNCT02067572Not applicable1 country
- Palifermin for the Reduction of Oral Mucositis in Patients With Locally Advanced Head and Neck CancerCompletedNCT00101582Phase 3
- Aphtostomatitis and Mucositis Treatment by Natural Herbal Formula (Sorend®)Status unknownNCT013213071 country
- Phototherapy for the Management of Oral Ulcers in Bone Marrow RecipientsCompletedNCT01307540Not applicable
- Diet and Lifestyle Intervention Study in Postpartum Women in ChinaStatus unknownNCT01039051Phase 2/31 country
- The Effectiveness of Pasteurized Goat Milk in the Treatment of Childhood Oral Ulcer DiseasesCompletedNCT00333749Phase 11 country