Drug
Vancomycin clinical trials
Also written Firvanq.
How each study uses Vancomycin is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
Get an email when these change. Save the Vancomycin studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Approvals
The first approval found in each region, with its record
- United States
- 6 Nov 1964 · VANCOCIN HYDROCHLORIDE · ANDA 060180 (FDA, Drugs@FDA)
- European Union
- Not in EMA's list of EU-wide authorisations
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
How studies write it
Studies that test it under each name
Studies by the year they started
175 studies that test it; most in 2018 (14); 1 more planned to start later
| Year | Studies |
|---|---|
| 1997 | 1 |
| 2000 | 1 |
| 2001 | 1 |
| 2002 | 2 |
| 2004 | 1 |
| 2005 | 4 |
| 2006 | 2 |
| 2007 | 1 |
| 2008 | 1 |
| 2009 | 3 |
| 2010 | 7 |
| 2011 | 6 |
| 2012 | 13 |
| 2013 | 6 |
| 2014 | 9 |
| 2015 | 9 |
| 2016 | 7 |
| 2017 | 10 |
| 2018 | 14 |
| 2019 | 11 |
| 2020 | 8 |
| 2021 | 10 |
| 2022 | 11 |
| 2023 | 11 |
| 2024 | 10 |
| 2025 | 6 |
| 2026 | 10 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 13 · Other 163
Mayo Clinic (5) · University of Minnesota (4) · Pfizer (4) · Assiut University (4) · Hamilton Health Sciences Corporation (4) · Medical College of Wisconsin (3) · NYU Langone Health (3) · University of Tennessee (3)
Often tested with
Tested in the same studies.
Cefazolin (9) · Metronidazole (8) · Gentamicins (7) · Tobramycin (7) · Fidaxomicin (6) · Neomycin (6) · Linezolid (6) · Daptomycin (6)
Coming up
From the study records. Dates are the sponsors’ own estimates and often move.
Reaching primary completion within a year · 14, 2 in phase 3
Studies that test Vancomycin, phase 3 first.
- Dec 2026Enteral Vancomycin as Primary Prophylaxis Against Clostridioides Difficile Infection in Critically Ill PatientsPhase 2/3 · Riverside University Health System Medical Center
- Jan 2027Intramedullary Calcium Sulfate Antibiotic DepotPhase 3 · Wake Forest University Health Sciences
- Dec 2026Vancomycin in TKAsPhase 4 · University of California, San Diego
- Jan 2027A Phase 1/2 Study to Evaluate the Safety, PK and Efficacy of TNP-2092 Administered Via IA Injection in PJI ParticipantsPhase 1/2 · TenNor Therapeutics Inc.
- Jan 2027Can Intraosseous Antibiotics Improve the Results of Irrigation & Debridement and Prosthetic Retention for PJI?Phase 4 · OrthoCarolina Research Institute, Inc.
- Mar 2027Haemoglobin And Vancomycin Pharmacokinetics in the Cerebrospinal Fluid Following Subarachnoid HaemorrhageNot applicable · University Hospital Southampton NHS Foundation Trust
- Mar 2027Evaluating the Efficacy and Safety of Intra-wound Vancomycin Powder in High Risk PatientsNot applicable · The University of Hong Kong
- Mar 2027Evaluation of an Oral Microbiota-based Therapeutic as a Treatment Option for PSCEarly Phase 1 · University of Minnesota
- May 2027Efficacy and Cost-Effectiveness of Topical Vancomycin Powder in Preventing Pediatric Ventriculoperitoneal Shunt Infections Across Different EtiologiesPhase 4 · Assiut University
- May 2027Novel Biomarkers of Non-IgE Immediate Hypersensitivity Drug ReactionsPhase 1/2 · Johns Hopkins University
Studies
Open first, then newest update. How each study uses Vancomycin is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 176
- A Phase 1/2 Study to Evaluate the Safety, PK and Efficacy of TNP-2092 Administered Via IA Injection in PJI ParticipantsRecruitingPhase 1/2TenNor Therapeutics Inc.NCT06889701Written as Vancomycin Hydrochloride for Injection (IA)
- Intramedullary Calcium Sulfate Antibiotic DepotRecruitingPhase 3Wake Forest University Health SciencesNCT05766670Written as Vancomycin Hydrochloride
- Investigation of Vancomycin Efficacy in Patients With Ulcerative Colitis and Primary Sclerosing CholangitisRecruitingPhase 2McMaster UniversityNCT07341282Written as Vancomycin (blinded)
- Placement of Antibiotic Powder in Wounds During the Emergency RoomRecruitingPhase 4The University of Texas Health Science Center at San AntonioNCT03765567Written as Vancomycin
- Vancomycin Study in Multiple Sclerosis (MS)RecruitingPhase 1Icahn School of Medicine at Mount SinaiNCT05539729Written as Vancomycin
- Vancomycin Taper to Prevent Recurrent Clostridioides DifficileRecruitingPhase 3McGill University Health Centre/Research Institute of the McGill University Health CentreNCT07328971Written as Vancomycin capsule
- Antibiotics and Vaccine Immune Responses StudyRecruitingPhase 4South Australian Health and Medical Research InstituteNCT06148025Written as Vancomycin Oral Capsule
- Vancomycin Efficacy in Response to Dysbiosis in Atypical ColitisNot yet recruitingPhase 2Tampere University HospitalNCT07646223Written as Oral Vancomycin
- A Clinical Trial Evaluating Fecal Microbiota Transplantation (FMT) in Adolescents With ADHDNot yet recruitingPhase 2University of CalgaryNCT07756255Written as Vancomycin 250mg BID
- Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT 2RecruitingPhase 3Major Extremity Trauma Research ConsortiumNCT04678154Written as Vancomycin and Tobramycin
- Antibiotic Impregnated Bone Graft to Reduce Infection in Hip Replacement.RecruitingPhase 2University Hospital, LinkoepingNCT05169229Written as Vancomycin + Tobramycin
- A Study of Antibiotic Delivery to Prevent Infection After Breast Tissue Expander PlacementRecruitingPhase 4Memorial Sloan Kettering Cancer CenterNCT07220967Written as Vancomycin and Gentamicin
- Radiation, Oral Vancomycin, and CAR-T for B-Cell LymphomasRecruitingPhase 1Abramson Cancer Center at Penn MedicineNCT07478848Written as Vancomycin 125mg
- Evaluation of Microbiota Transplant Therapy in Patients With Alopecia AreataRecruitingPhase 2University of MinnesotaNCT06747611Written as Vancomycin, Neomycin and MTT capsules
- Vancomycin in TKAsRecruitingPhase 4University of California, San DiegoNCT07282782Written as Vancomycin
- Infection Prophylaxis in Total Joint ReplacementRecruitingPhase 3Hamilton Health Sciences CorporationNCT06126614Written as Vancomycin Hydrochloride
- Evaluation of an Oral Microbiota-based Therapeutic as a Treatment Option for PSCRecruitingEarly Phase 1University of MinnesotaNCT06197308Written as oral vancomycin and oral amoxicillin
- Staphylococcus Aureus Network Adaptive Platform TrialRecruitingPhase 4University of MelbourneNCT05137119Written as Vancomycin
- Efficacy and Cost-Effectiveness of Topical Vancomycin Powder in Preventing Pediatric Ventriculoperitoneal Shunt Infections Across Different EtiologiesNot yet recruitingPhase 4Assiut UniversityNCT07547826Written as Topical Vancomycin Powder
- Can Intraosseous Antibiotics Improve the Results of Irrigation & Debridement and Prosthetic Retention for PJI?Enrolling by invitationPhase 4OrthoCarolina Research Institute, Inc.NCT03713528Written as Intraoperative Intraosseous Vancomycin
See all 176 studies that test Vancomycin →
Given beside what is tested · 39 — Vancomycin is usual care or a partner of the new treatment
- Safety, Dosage, and Microbiome Engraftment Study of MGT-006 for Ulcerative Colitis (ROOT Study)RecruitingPhase 1/2Metagen Therapeutics, Inc.NCT07913347Written as Vancomycin hydrochloride
- A Phase 2b Study to Evaluate the Efficacy, Safety, and PK Profiles of TNP-2092 Administered Via IA Injection in PJI ParticipantsRecruitingPhase 2TenNor Therapeutics (Zhongshan) LimitedNCT07858916Written as Vancomycin Hydrochloride for Injection
- Intestinal Microbiota Transplantation in Patients With Chronic Heart FailureRecruitingPhase 1Melana Yuzefpolskaya, MDNCT07490054Written as Vancomycin
- Intraoperative Placement of Vancomycin-impregnated Calcium Sulfate Beads Conjugated With Analgesics to Improve Spine Surgery OutcomesNot yet recruitingPhase 2Ganesh M. ShankarNCT07201987Written as Vancomycin (local, via calcium sulfate beads)
- A Pragmatic Clinical Trial Comparing the Risk of Acute Kidney Injury During Treatment With Vancomycin and Piperacillin-Tazobactam vs. Vancomycin and Cefepime in Hospitalized PatientsRecruitingPhase 4University of PennsylvaniaNCT06954129Written as Vancomycin
- Combination Study of Antibiotics With Enzalutamide (PROMIZE)RecruitingPhase 1/2Institute of Cancer Research, United KingdomNCT06126731Written as Vancomycin 125mg
- Fecal Microbiota Transfer in Liver Cancer to Overcome Resistance to Atezolizumab/Bevacizumab (FLORA)RecruitingPhase 2Michael DillNCT05690048Written as Vancomycin Oral Capsule
- Microbiota Transfer Therapy for Children and Adults With Both Pitt Hopkins Syndrome and Gastrointestinal DisordersRecruitingPhase 2Gut-Brain-Axis Therapeutics Inc.NCT06321796Written as Vancomycin
- VE416 for Treatment of Food AllergyRecruitingPhase 1/2Massachusetts General HospitalNCT03936998Written as Vancomycin plus VE416 before PNOIT
- A Phase 1b Trial to Evaluate the Safety of MB310 in Patients With Active, Mild-to-Moderate Ulcerative ColitisCompletedPhase 1Microbiotica LtdNCT06582264Written as Vancomycin
- Fecal Microbiota Transplant and Re-introduction of Anti-PD-1 Therapy (Pembrolizumab or Nivolumab) for the Treatment of Metastatic Colorectal Cancer in Anti-PD-1 Non-respondersActive, not recruitingPhase 2M.D. Anderson Cancer CenterNCT04729322Written as Vancomycin
- Postoperative Antibiotic Management Duration Following Surgery for Intravenous Drug Abuse (IVDA) Endocarditis (OPTIMAL)TerminatedPhase 4West Virginia UniversityNCT05156437Written as Ampicillin, Oxacillin, Vancomycin, Daptomycin, Ceftriaxone, Cefepime, Ceftaroline
- PHASE II SINGLE-CENTER, RANDOMIZED, OPEN-LABEL, PROSPECTIVE, STUDY TO DETERMINE THE IMPACT OF SERIAL PROCALCITONINCompletedPhase 2M.D. Anderson Cancer CenterNCT04983901Written as Vancomycin
- Precision Dosing of Vancomycin in Critically Ill ChildrenCompletedPhase 4University Hospital, GhentNCT04666948Written as Vancomycin
- VE202 in Patients With Mild-to-Moderate Ulcerative ColitisTerminatedPhase 2Vedanta Biosciences, Inc.NCT05370885Written as Vancomycin Oral Capsule
- Study of VE800 and Nivolumab in Patients With Selected Types of Advanced or Metastatic CancerCompletedPhase 1/2Vedanta Biosciences, Inc.NCT04208958Written as Vancomycin Oral Capsule
- Beneficial Bacteria Treatment for AutismCompletedPhase 1/2Arizona State UniversityNCT02504554Written as oral Vancomycin
- Effectiveness of Adding Morphine to Intraosseous Vancomycin for Pain Control in Total Knee ArthroplastyCompletedPhase 2Carilion ClinicNCT06716749Written as Vancomycin
- A Phase 2a Study, Effect of Vancomycin With vs Without Delpazolid (LCB01-0371) in Patients With MRSA BacteremiaTerminatedPhase 2LigaChem Biosciences, Inc.NCT05225558Written as Vancomycin
- VE303 for Treatment of Hepatic Encephalopathy (HE)CompletedPhase 2Patricia BloomNCT04899115Written as oral vancomycin
Showing 20 of 39.
As the comparator · 96 — what is tested is compared with Vancomycin
- Daptomycin vs. Vancomycin for the Treatment of Methicillin Resistant S. Aureus BacteremiaRecruitingPhase 4Todd C. Lee MD MPH FIDSANCT06637332Written as Vancomycin (IV)
- Irrisept Solution for Instrumented Spine SurgeryRecruitingNot applicableRhode Island HospitalNCT06439953Written as Vancomycin
- IO Vancomycin SpineNot yet recruitingPhase 2/3The Methodist Hospital Research InstituteNCT06748144Written as Intravenous Vancomycin
- Linezolid or Vancomycin Surgical Site Infection ProphylaxisRecruitingPhase 4Assistance Publique Hopitaux De MarseilleNCT05571722Written as Vancomycin Injection
- Intraosseous Vs. Intravenous Vancomycin Administration in Total Ankle ArthroplastyRecruitingPhase 4The Methodist Hospital Research InstituteNCT06384651Written as Intravenous Vancomycin
- Pulsed Electromagnetic Field Stimulation and Charcot Foot UlcerRecruitingNot applicableCairo UniversityNCT06527131Written as Vancomycin
- Lyophilized Fecal Microbiome Transfer vs. Vancomycin Monotherapy for Primary Clostridioides Difficile InfectionRecruitingNot applicableRambam Health Care CampusNCT05709184Written as Vancomycin
- Randomized, Multicenter, Double-blind, Vancomycin-controlled Study to Evaluate the Efficacy of Ethanol Lock Solution for the Curative Treatment of Implantable Venous Access Port Infection Due to Coagulase-negative StaphylococciCompletedNot applicableUniversity Hospital, Clermont-FerrandNCT02411331Written as Vancomycine 5 mg/ml + Héparine 2500UI/ml
- Comparison of Ridinilazole Versus Vancomycin Treatment for Clostridium Difficile InfectionCompletedPhase 3Summit TherapeuticsNCT03595553Written as Vancomycin
- Ceftobiprole in the Treatment of Patients With Acute Bacterial Skin and Skin Structure InfectionsCompletedPhase 3Basilea PharmaceuticaNCT03137173Written as vancomycin+aztreonam
- Study to Assess Safety, Tolerability and Efficacy of Afabicin in The Treatment of Participants With Bone or Joint Infection Due to StaphylococcusTerminatedPhase 2Debiopharm International SANCT03723551Written as Vancomycin
- Intraosseous Versus Intravenous Vancomycin in Below-Knee Amputation for Ischemic Diabetic FootCompletedPhase 4Başakşehir Çam & Sakura City HospitalNCT07338773Written as Intravenous Vancomycin
- Comparison of Cadazolid Versus Vancomycin in Children With Clostridium Difficile-associated Diarrhea (CDAD)TerminatedPhase 2/3ActelionNCT03105479Written as Vancomycin capsule
- Efficacy and Safety of Cadazolid Versus Vancomycin in Subjects With Clostridium Difficile - Associated DiarrheaCompletedPhase 3ActelionNCT01987895Written as Vancomycin
- Efficacy and Safety of Cadazolid Versus Vancomycin in Subjects With Clostridium Difficile-associated DiarrheaCompletedPhase 3ActelionNCT01983683Written as Vancomycin
- ACX-362E [Ibezapolstat] for Oral Treatment of Clostridioides Difficile InfectionCompletedPhase 2Acurx Pharmaceuticals Inc.NCT04247542Written as Vancomycin
- DOTS: Dalbavancin as an Option for Treatment of Staphylococcus Aureus BacteremiaCompletedPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT04775953Written as Vancomycin
- A Study to Investigate the Safety and Efficacy of Fidaxomicin (Oral Suspension or Tablets) and Vancomycin (Oral Liquid or Capsules) in Pediatric Subjects With Clostridium Difficile-associated Diarrhea (CDAD)CompletedPhase 3Astellas Pharma Europe B.V.NCT02218372Written as Vancomycin capsules
- A Study to Compare Safety and Efficacy of OPT-80(Fidaxomicin) With Vancomycin in Subjects With Clostridium Difficile-associated Diarrhea (CDAD)CompletedPhase 3Astellas Pharma IncNCT02179658Written as vancomycin
- Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections in Children, Known or Suspected to be Caused by Susceptible Gram-positive Organisms, Including MRSACompletedPhase 3AbbVieNCT02814916Written as Vancomycin
Showing 20 of 96.
Codes
What other systems call Vancomycin · ClinicalTrials.gg INT008395
- MeSH (NLM) D014640VancomycinConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 6Q205EH1VUVANCOMYCINConfirmed FDA, NLM, Wikidata
- RxNorm 11124Confirmed FDA, Wikidata
- Wikidata Q424027vancomycinConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C925VancomycinConfirmed FDA, Wikidata
- DrugBank DB00512One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D014640 | Vancomycin | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 6Q205EH1VU | VANCOMYCIN | Confirmed FDA, NLM, Wikidata |
| RxNorm | 11124 | — | Confirmed FDA, Wikidata |
| Wikidata | Q424027 | vancomycin | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C925 | Vancomycin | Confirmed FDA, Wikidata |
| DrugBank | DB00512 | — | One source Wikidata |
Also registered as vancomycin hydrochloride (UNII 71WO621TJD · RxNorm 66955).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.