Clostridium Infections clinical trials
The registry lists 251 studies for Clostridium Infections across more than 10 countries. 51 are recruiting or about to start. 222 of them are mainly about Clostridium Infections (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 3 narrower conditions too, such as Tetanus: 621 studies, 85 open.
Get an email when these change. Save the Clostridium Infections studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
See an example email
Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Who runs them
Brigham and Women's Hospital (5) · University of Wisconsin, Madison (5) · Mayo Clinic (5) · Actelion (5) · Summit Therapeutics (4) · Rebiotix Inc. (4) · Medical College of Wisconsin (4) · Assistance Publique - Hôpitaux de Paris (4)
What is being tested here
Drugs under test in Clostridium Infections studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Drug classes tested here Proton pump inhibitors (PPIs) 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026Enteral Vancomycin as Primary Prophylaxis Against Clostridioides Difficile Infection in Critically Ill Patients · Phase 3 · Riverside University Health System Medical Center
- Apr 2027Fecal Microbiota Transplantation in Clostridioides Difficile Infection First Episode and First Recurrence · Phase 3 · Benoit Guery
- Jun 2027VE303 for Prevention of Recurrent Clostridioides Difficile Infection · Phase 3 · Vedanta Biosciences, Inc.
- Nov 2026Clostridioides Difficile Infection: Analyzing CLInic Evolution and Bacterial Clearance · Fondation Hôpital Saint-Joseph
- Dec 2026Study on Clostridium Difficile Infection in Infants · First People's Hospital of Hangzhou
- Dec 2026Alanyl-glutamine Supplementation for C. Difficile Treatment (ACT) · University of Virginia
- Jan 2027Epidemiology of Clostridioides Difficile Infection (CDI) in Long-term Care Facilities, Assessment of Professional Practices Related to CDI Risk Prevention, and Strategies for Improving Care. · Assistance Publique Hopitaux De Marseille
- Jan 2027C. Difficile Toxin Levels in Stool From Healthy Individuals Following Standard of Care Antibiotic Treatment for CDI. · Bactolife A/S
- Feb 2027Changes in Recipients Gut Microbiota After Fecal Microbiota Transplantation · Fondazione Policlinico Universitario Agostino Gemelli IRCCS
- Feb 2027FMT in Initial CDI · Turku University Hospital
Who these studies take
Of the 36 Clostridium Infections studies recruiting now, 22 (61%) set no upper age limit and 8 (22%) stop at 75 or younger. 9 (25%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 3 (8%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 5 (14%) | 5 (14%) |
| 18 | 33 (92%) | 33 (92%) |
| 30 | 33 (92%) | 33 (92%) |
| 40 | 33 (92%) | 33 (92%) |
| 50 | 32 (89%) | 32 (89%) |
| 65 | 32 (89%) | 32 (89%) |
| 75 | 31 (86%) | 31 (86%) |
| 85 | 28 (78%) | 28 (78%) |
Across all 251 studies, recruiting or not: 14% stop at 75 or younger and 10% at 65; 18% take children; <1% are for women only and <1% for men only; 13% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Clostridium Infections studies take
Of 23 phase 2 interventional studies under Clostridium Infections, half reached primary completion within 23 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 21 mo13–28 · 14 studies | — | — |
| Phase 2 | 23 mo19–39 · 23 studies | — | — |
| Phase 3 | 37 mo34–46 · 23 studies | — | — |
| Interventional, no phase | 29 mo9–37 · 27 studies | — | — |
| Observational | 31 mo22–… · 26 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 14, 2026.
Started recruiting3
- A Safety Trial to Evaluate an Orally Ingested Yeast Modified to Express a Tetra-specific Anti-toxin for Clostridioides DifficileNov 10, 2026NCT07649096
- Prevention of Recurrence of Clostridioides Difficile Colitis With Ursodeoxycholic Acid (UCDA) as a Supplement to Standard TherapyNov 2, 2026NCT06884748
- Fecal Microbiota Transplantation (FMT) for Clostridium DifficileOct 16, 2026NCT03712722
Studies
Recruiting first, then most recently updated. Showing 50 of 251. Browse all 251 → or search them.
- Prevention of Recurrent C. Difficile Infection Study With AZD5148 Monoclonal AntibodyRecruitingNCT07285213Phase 214 countries
- A Safety Trial to Evaluate an Orally Ingested Yeast Modified to Express a Tetra-specific Anti-toxin for Clostridioides DifficileRecruitingNCT07649096Phase 11 country
- ACX-362E [Ibezapolstat] for Oral Treatment of Recurrent Clostridioides Difficile InfectionRecruitingNCT07513285Phase 21 country
- VE303 for Prevention of Recurrent Clostridioides Difficile InfectionRecruitingNCT06237452Phase 324 countries
- Epidemiology of Clostridioides Difficile Infection (CDI) in Long-term Care Facilities, Assessment of Professional Practices Related to CDI Risk Prevention, and Strategies for Improving Care.Not yet recruitingNCT079206271 country
- Prevention of Recurrence of Clostridioides Difficile Colitis With Ursodeoxycholic Acid (UCDA) as a Supplement to Standard TherapyRecruitingNCT06884748Early Phase 11 country
- Evaluation of EXL01, a New Live Biotherapeutic Product to Prevent Recurrence of Clostridioides Difficile Infection in High-risk PatientsRecruitingNCT06306014Phase 1/21 country
- Fecal Microbiota Transplantation (FMT) for Clostridium DifficileRecruitingNCT037127221 country
- Natural History of Clostridioides Difficile InfectionRecruitingNCT048018621 country
- Intestinal Microbiota Transplantation in Patients Undergoing Colon ResectionRecruitingNCT06370884Phase 11 country
- A Clinical Trial of Resistant Potato Starch for Gut MDRO DecolonizationNot yet recruitingNCT07792915Phase 21 country
- Safety Registry of a Fecal Microbiota Transplant CohortRecruitingNCT063110061 country
- Fecal Microbiota Transplantation in Clostridioides Difficile Infection First Episode and First RecurrenceRecruitingNCT05266807Phase 31 country
- Lifestyle and Recurrent Clostridioides Difficile Infection (CDI)RecruitingNCT07613645Not applicable1 country
- Secondary Prevention of Clostridioides Difficile Using VancomycinRecruitingNCT06979609Phase 2/31 country
- Role of Bile Acids and Microbiota in Clostridioides Difficile Infection in Ulcerative ColitisRecruitingNCT062283521 country
- Fecal Microbiota Transplantation in an Expanded Ulcerative Colitis PopulationRecruitingNCT07401680Phase 11 country
- Long-Term Outcomes After CDI: FMT Versus Antibiotic-Only TreatmentNot yet recruitingNCT075693801 country
- FMT Capsules for rCDIRecruitingNCT07458984Phase 31 country
- Changes in Recipients Gut Microbiota After Fecal Microbiota TransplantationRecruitingNCT057398251 country
- Fecal Microbiota Transplantation (FMT): PRIM-DJ2727AvailableNCT03786900
- Clostridioides Difficile Infection: Analyzing CLInic Evolution and Bacterial ClearanceRecruitingNCT060302451 country
- Xylitol Use for Decolonization of C. Difficile in Patients With IBDNot yet recruitingNCT05852587Phase 11 country
- Outcomes and Data Collection for Fecal Microbiota Transplantation for the Treatment of Recurrent Clostridium DifficileRecruitingNCT03562741Not applicable1 country
- Clostridioides Difficile: Understanding Responses and Treatment EffectsRecruitingNCT073740941 country
- Fecal Microbiota Transplant National RegistryRecruitingNCT033258552 countries
- Pilot Trial of Xylitol for C. Difficile De-Colonization in Patients With Inflammatory Bowel DiseaseNot yet recruitingNCT06799039Early Phase 11 country
- Enteral Vancomycin as Primary Prophylaxis Against Clostridioides Difficile Infection in Critically Ill PatientsRecruitingNCT07221370Phase 2/31 country
- Use of Fidaxomicin Compared to Vancomycin for Decolonization of C. Difficile in Patients With Inflammatory Bowel DiseaseNot yet recruitingNCT06794944Phase 41 country
- STOP-CDI: Efficacy of Fecal Microbiota Transplantation vs Fidaxomicin vs Vancomycin in Treating and Preventing Relapse of Clostridioides Difficile InfectionNot yet recruitingNCT07120490Not applicable
- A Flexible Clinical Trial to Test if Freeze-dried Fecal Microbiota Therapy Helps Treat Diarrhea-predominant Irritable Bowel Syndrome or Prevent Recurring C. Difficile Infections.Not yet recruitingNCT06948461Phase 2
- Fecal Microbiota Transplantation for C Diff InfectionRecruitingNCT01905709Not applicable1 country
- FMT in Initial CDIRecruitingNCT05257538Not applicable1 country
- Prevention of Clostridium Difficile Infections Using Lactobacillus Plantarum 299v Strain in Nephrology and Transplantation DepartmentRecruitingNCT06859437Not applicable1 country
- CMTS0929 for Clostridioides Difficile InfectionNot yet recruitingNCT06836427Early Phase 11 country
- Study of Clostridioides Difficile in InfantsRecruitingNCT067887691 country
- Study on Clostridium Difficile Infection in InfantsRecruitingNCT067039181 country
- Alanyl-glutamine Supplementation for C. Difficile Treatment (ACT)RecruitingNCT04305769Phase 21 country
- Safety and Efficacy of Fecal Microbiota TransplantationRecruitingNCT04014413Not applicable1 country
- A Study to Assess the Effect of Doctor's Biome Medical Food in Individuals With Clostridium Difficile InfectionNot yet recruitingNCT06367504Not applicable1 country
- Virus as Treatment of C. Difficile Infection (VISION)Not yet recruitingNCT06398379Not applicable1 country
- Lyophilized Fecal Microbiome Transfer vs. Vancomycin Monotherapy for Primary Clostridioides Difficile InfectionRecruitingNCT05709184Not applicable6 countries
- Treatment of CDI and Recurrence With Fecal Microbiota Transplant Using PromicrobiomaNot yet recruitingNCT06107569Phase 3
- Rescue Fecal Microbiota Transplantation for National Refractory Intestinal InfectionsRecruitingNCT038955931 country
- Research on Gut Microbiome and Metabolomics Alterations in C.Difficile Infected IBD PatientsRecruitingNCT057145661 country
- Washed Microbiota Transplantation for Clostridioides Difficile InfectionRecruitingNCT061066981 country
- Clostridioides Difficile ColonisationRecruitingNCT05693077Phase 11 country
- L. Plantarum 299v and Gut Microbiome, Diarrhoea, and Clostridioides Difficile Infection in Colorectal Cancer PatientsRecruitingNCT06019312Not applicable1 country
- Fecal Filtrate as a Treatment Option of Multiple Recurrent Clostridioides Difficile InfectionNot yet recruitingNCT04960306Phase 31 country
- Faecal Bacteriotherapy for Postantibiotic Diarrhoea in Critically Ill PatientsRecruitingNCT05430269Not applicable1 country