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Drug

Trazodone clinical trials

Also written Desyrel.

studies test it
50
open now
12
in phase 3
10
first study started
2000

How each study uses Trazodone is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study

Get an email when these change. Save the Trazodone studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.

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Example · made-up studies

Breast cancer · Recruiting: 2 came in, 3 changed

What changed in your saved searches, Oct 31 – Nov 6:

A study of drug A after surgery for early breast cancer

Came in · now Recruiting

Drug B with hormone therapy in advanced breast cancer

Changed

· Sites: 4 added, including Seoul and Busan

· Enrollment: 300 → 450 participants

Exercise during chemotherapy

Now Active, not recruiting

One email a week for all your saved searches. Stop any time.

Approvals

The first approval found in each region, with its record

United States
24 Dec 1981 · DESYREL · NDA 018207 (FDA, Drugs@FDA)
European Union
Not in EMA's list of EU-wide authorisations

From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out

How studies write it

Studies that test it under each name

Name

Trazodone
34
Oleptro
7
Trazodone HCl
4
Trazodone 20 mg
2

Brand

Desyrel
8
Trittico®
1

Studies by the year they started

49 studies that test it; most in 2017 (5); 1 more planned to start later

Studies that test Trazodone, by start year
YearStudies
20001
20021
20052
20071
20084
20091
20102
20114
20123
20131
20153
20175
20182
20191
20202
20212
20222
20232
20244
20252
20264

By phase

A phase 1/2 study counts in both.

Early Phase 1
3
Phase 1
12
Phase 2
11
Phase 3
10
Phase 4
13
No phase
5

What it is tested for

Each study’s main condition, where its own words name it, so a study counts once.

Sleep Initiation and Maintenance Disorders
11
Sleep Apnea, Obstructive
4
Depressive Disorder, Major
3
Sleep Apnea Syndromes
3
Depression
2
Depression, Postpartum
2
Delirium
2
Cognitive Dysfunction
1
Stress Disorders, Post-Traumatic
1
Spinal Cord Injuries
1
Diabetic Neuropathies
1
Fibromyalgia
1

Who runs them

Industry 12 · Other 38

Labopharm Inc. (5) · Aziende Chimiche Riunite Angelini Francesco S.p.A (4) · Brigham and Women's Hospital (4) · VA Office of Research and Development (3) · University of Washington (2) · Milton S. Hershey Medical Center (2) · Lee's Pharmaceutical Limited (2) · Centre hospitalier de l'Université de Montréal (CHUM) (2)

Often tested with

Tested in the same studies.

Zolpidem (4) · Quetiapine (4) · Diphenhydramine (3) · Eszopiclone (2) · Fluoxetine (2) · Fluvoxamine (2) · Paroxetine (2) · Sertraline (2)

Coming up

From the study records. Dates are the sponsors’ own estimates and often move.

Reaching primary completion within a year · 4

Studies that test Trazodone.

Studies

Open first, then newest update. How each study uses Trazodone is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.

Testing it · 50

See all 50 studies that test Trazodone →

Given beside what is tested · 1 — Trazodone is usual care or a partner of the new treatment
As the comparator · 3 — what is tested is compared with Trazodone

Codes

What other systems call Trazodone · ClinicalTrials.gg INT008344

  • MeSH (NLM) D014196TrazodoneConfirmed ClinicalTrials.gov, NLM, Wikidata
  • UNII (FDA) YBK48BXK30TRAZODONEConfirmed FDA, NLM, Wikidata
  • RxNorm 10737Confirmed FDA, Wikidata
  • Wikidata Q411457trazodoneConfirmed FDA, NLM, Wikidata
  • NCI Thesaurus C29510TrazodoneOne source FDA
  • DrugBank DB00656One source Wikidata

Also registered as trazodone hydrochloride (UNII 6E8ZO8LRNM · RxNorm 82112).

“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.