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Thioctic Acid clinical trials
Also written Alpha lipoic acid.
- studies test it
- 119
- open now
- 22
- in phase 3
- 25
- first study started
- 1995
Keep track of what changes. Save the Thioctic Acid studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
117 studies that test it; most in 2026 (11)
| Year | Studies |
|---|---|
| 1995 | 1 |
| 1998 | 1 |
| 2000 | 1 |
| 2002 | 1 |
| 2003 | 2 |
| 2004 | 3 |
| 2005 | 3 |
| 2006 | 3 |
| 2007 | 2 |
| 2008 | 2 |
| 2009 | 7 |
| 2010 | 10 |
| 2011 | 6 |
| 2012 | 1 |
| 2013 | 6 |
| 2014 | 4 |
| 2015 | 4 |
| 2016 | 6 |
| 2017 | 1 |
| 2018 | 6 |
| 2019 | 6 |
| 2020 | 3 |
| 2021 | 2 |
| 2022 | 3 |
| 2023 | 10 |
| 2024 | 6 |
| 2025 | 6 |
| 2026 | 11 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 3
- Phase 1
- 17
- Phase 2
- 41
- Phase 3
- 25
- Phase 4
- 16
- No phase
- 35
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 8 · Other 111
Ain Shams University (14) · Augusta University (6) · Oregon Health and Science University (6) · Damanhour University (3) · VA Office of Research and Development (3) · National Center for Complementary and Integrative Health (NCCIH) (3) · Shanghai Zhongshan Hospital (2) · Oregon State University (2)
Often tested with
Tested in the same studies.
Vitamin E (12) · Ascorbic Acid (9) · Acetylcysteine (5) · Acetylcarnitine (4) · Sapropterin (4) · Omega-3 fatty acid (3) · Resveratrol (2) · Magnesium (2)
Studies
Open first, then newest update. How each study uses Thioctic Acid is read from its arms, and is right about nine times in ten.
Testing it · 119
- Trial of the Combination of Alpha-Lipoic Acid and Mirabegron in Women and in Men With ObesityNot yet recruitingPhase 2National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NCT05713799Written as Alpha-lipoic acid
- Alpha-Lipoic Acid as an Adjunct to Non-Surgical Periodontal Treatment in GingivitisRecruitingNot applicableBiruni UniversityNCT07882394Written as Alpha-Lipoic Acid 200 mg
- Comparative Study of Combination Treatment of Bionerv E+ Versus Vitamin B Complex in Treatment of Diabetic Polyneuropathy in Type 2 Diabetic Patients and Its Effect on Wound HealingRecruitingNot applicableBREGO Life SciencesNCT07877948Written as Alpha-Lipoic Acid, Vitamin B1, Vitamin B6, Vitamin B12, Vitamin E
- : Vascular Function in Health and DiseaseRecruitingPhase 1D. Walter WrayNCT02966665Written as BH4, L-NMMA, Vitamin C, Vitamin E, α-Lipoic Acid and L-Ascorbate
- Efficacy and Safety of Low-Dose Duloxetine Plus Alpha-Lipoic Acid Versus Standard-Dose Duloxetine in Painful Diabetic Peripheral NeuropathyNot yet recruitingNot applicableBangladesh Medical UniversityNCT07785544Written as Alpha-Lipoic Acid
- Efficacy of Lipoic Acid on Chronic Ischemic Heart Failure PatientsNot yet recruitingPhase 3Shanghai Zhongshan HospitalNCT07725484Written as Alpha-Lipoic Acid (ALA)
- Protective Role of Alpha-Lipoic Acid in Chemotherapy-Induced MucositisRecruitingPhase 2/3Ain Shams UniversityNCT07736495Written as alpha lipoic acid 600 mg twice daily
- Alpha-Lipoic Acid Supplementation and IVF Outcomes in Women of Advanced Maternal AgeRecruitingNot applicableKaohsiung Veterans General Hospital.NCT07685431Written as Alpha-Lipoic Acid (ALA)
- Efficacy of Alpha Lipoic Acid Combined With Myo-Inositol in Non-Diabetic PCOS PatientsRecruitingPhase 3Beni-Suef UniversityNCT07630779Written as Alpha Lipoic Acid
- Clinical Effects of Alpha-Lipoic Acid in Advanced NSCLCNot yet recruitingPhase 2Ain Shams UniversityNCT07574684Written as Alpha Lipoic Acid 600mg
- Alpha-Lipoic Acid in Mitigating Cisplatin-Induced NephrotoxicityRecruitingPhase 2Minia UniversityNCT07564479Written as Alpha-Lipoic Acid (ALA)
- Effect of Low-Dose Versus High-Dose Alpha-Lipoic Acid on Oxidative Stress, Inflammation, and Clinical Outcomes in Acute Exacerbations of Chronic Obstructive Pulmonary DiseaseNot yet recruitingPhase 3Ain Shams UniversityNCT07456176Written as Alpha Lipoic Acid 600 MG Oral Tablets
- Alpha Lipoic Acid in Pediatrics on HemodialysisEnrolling by invitationPhase 3Ain Shams UniversityNCT06286098Written as Alpha lipoic acid
- Effects of Lower Body Positive Pressure Therapy Versus Alpha Lipoic Acid and Omega-3 Fatty Acids on Knee OsteoarthritisNot yet recruitingPhase 3Badr UniversityNCT07399743Written as Alpha-Lipoic Acid (ALA)+PT
- Comparing N-Acetylcysteine (NAC) Versus Alpha-Lipoic Acid (ALA) as Adjuncts for Postoperative Pain Management After Laparoscopic AppendectomyNot yet recruitingNot applicableAin Shams UniversityNCT07360379Written as Alpha-Lipoic Acid (ALA)
- Evaluation of the Effect of Alpha Lipoic Acid on Radiation Induced Dermatitis in Breast Cancer PatientsRecruitingNot applicableAin Shams UniversityNCT07256119Written as Alpha Lipoic Acid
- Effects of Adding Quercetin or Alpha Lipoic Acid to Usual Care on Symptoms and Blood Markers in Iraqi Women With Polycystic Ovary SyndromeRecruitingPhase 2Al-Mustansiriyah UniversityNCT07182526Written as Alpha Lipoic Acid 600 MG Oral Tablet
- Evaluating the Effect of N-Acetyl Cysteine and Alpha Lipoic Acid in Patients With Beta ThalassemiaNot yet recruitingPhase 3Tanta UniversityNCT07157722Written as Alpha Lipoic Acid 600 MG Oral Tablets
- Vascular Function and Oxidative Stress in Emergency Medical RespondersRecruitingNot applicableUniversity of DelawareNCT06985394Written as Antioxidant cocktail
- Effect of Alpha Lipoic Acid on Chemotherapy Induced Neurological Changes in Breast Cancer PatientsRecruitingPhase 4Ain Shams UniversityNCT06406127Written as Alpha Lipoic Acid 600 MG Oral Capsule
See all 119 studies that test Thioctic Acid →
As the comparator · 6 — what is tested is compared with Thioctic Acid
- Photobiomodulation Therapy vs. Alpha-Lipoic Acid in Burning Mouth Syndrome TreatmentActive, not recruitingNot applicableLu JiangNCT07381361Written as Alpha Lipoic Acid
- Pregabalin and Alpha-lipoic Acid Combination Versus Each Monotherapy in Patients With Diabetic Peripheral NeuropathyCompletedPhase 4Yuhan CorporationNCT04846673Written as Alpha-Lipoic Acid 480mg
- Caffeine vs. ALA in BMS Treatment. (BMS: Burning Mouth Syndrome. ALA: Alpha-Lipoic Acid.)CompletedNot applicableLu JiangNCT06195137Written as Alpha Lipoic Acid
- Clinical Study Evaluating the Safety and Efficacy of Roflumilast in Type 2 Diabetic Patients With Diabetic NeuropathyCompletedPhase 3Tanta UniversityNCT05369793Written as Alpha lipoic acid
- A Study of the Pharmacokinetics and Immunologic Effects of Lipoic Acid in Multiple SclerosisCompletedPhase 1Oregon Health and Science UniversityNCT00676156Written as oral lipoic acid (LA)
- Effects of Quinapril 40 mg With Alpha Lipoic Acid or Placebo on Diabetes and HypertensionCompletedNot applicableInVasc Therapeutics, Inc.NCT00795262Written as accupril, alpha lipoic acid
Codes
What other systems call Thioctic Acid · ClinicalTrials.gg INT007740
- MeSH (NLM) D008063Thioctic AcidConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 73Y7P0K73YALPHA LIPOIC ACIDConfirmed FDA, NLM, Wikidata
- RxNorm 6417Confirmed FDA, Wikidata
- Wikidata Q312229(RS)-thioctic acidConfirmed FDA, NLM, Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D008063 | Thioctic Acid | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 73Y7P0K73Y | ALPHA LIPOIC ACID | Confirmed FDA, NLM, Wikidata |
| RxNorm | 6417 | — | Confirmed FDA, Wikidata |
| Wikidata | Q312229 | (RS)-thioctic acid | Confirmed FDA, NLM, Wikidata |
Also registered as arlipoic acid (UNII VLL71EBS9Z).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.