Ono Pharmaceutical Co. Ltd clinical trials

The registry lists 157 studies whose lead sponsor is Ono Pharmaceutical Co. Ltd or one of 2 companies grouped under it. 25 are recruiting or about to start. Per ClinicalTrials.gov, last updated Oct 22, 2026.

Studies

Recruiting first, then most recently updated. Showing 50 of 157. Browse all 157 →

• INTREPID: A Study of Sapablursen Evaluating the Safety and Efficacy in Participants With Polycythemia Vera (PV)RecruitingNCT07429266Phase 3

  Sponsor listed in the registry: Ono Pharmaceutical Co., Ltd.

• IGNITE: Study of Tirabrutinib vs Rituximab and Temozolomide for Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL)RecruitingNCT07104032Phase 3

  Sponsor listed in the registry: Ono Pharmaceutical Co., Ltd.

• ONO-4538 Phase II Rollover Study (ONO-4538-98)RecruitingNCT04566380Phase 2

  Sponsor listed in the registry: Ono Pharmaceutical Co., Ltd.

• A Study to Evaluate the Safety, Efficacy, and PK of ONO-2017 in Japanese Patients With POS 2 to 17 Year OldsRecruitingNCT07594158Phase 3

  Sponsor listed in the registry: Ono Pharmaceutical Co., Ltd.

• A Study of ONO-4538HSC in Pediatric Patients With Malignant Solid Tumors and in Patients With Epithelioid Sarcoma.RecruitingNCT07734116Phase 1/2

  Sponsor listed in the registry: Ono Pharmaceutical Co., Ltd.

• Evaluate the Effect of Vimseltinib on P-glycoprotein (P-gp) Inhibition in Healthy Male ParticipantsRecruitingNCT07744802Phase 1

  Sponsor listed in the registry: Deciphera Pharmaceuticals, LLC · First submitted after Deciphera Pharmaceuticals, LLC became part of Ono Pharmaceutical Co. Ltd

• A Study of ONO-2020 in Patients With Agitation Associated With Alzheimer's Disease DementiaRecruitingNCT06803823Phase 2

  Sponsor listed in the registry: Ono Pharmaceutical Co., Ltd.

• A Study of DCC-3014 to Evaluate the Efficacy, Safety, and Pharmacokinetics in Subjects With TGCTNot yet recruitingNCT07832747Phase 2

  Sponsor listed in the registry: Ono Pharmaceutical Co., Ltd.

• A Trial of ONO-2808 in Participants With the Parkinsonian Subtype of Multiple System Atrophy (MSA-P)Not yet recruitingNCT07825402Phase 3

  Sponsor listed in the registry: Ono Pharmaceutical Co., Ltd.

• ONO-4915 in Patients With Primary Sjogren's DiseaseNot yet recruitingNCT07823790Phase 2

  Sponsor listed in the registry: Ono Pharmaceutical Co., Ltd.

• A Trial of ONO-4578 Versus Placebo in Combination With Nivolumab and Chemotherapy in Participants With Gastric Cancer, Esophagogastric Junction Cancer, or Esophageal AdenocarcinomaNot yet recruitingNCT07818070Phase 3

  Sponsor listed in the registry: Ono Pharmaceutical Co., Ltd.

• A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of ONO-6414 Administered Orally in Healthy Adult Participants and Patients With Active Ulcerative ColitisRecruitingNCT07749768Phase 1

  Sponsor listed in the registry: Ono Pharmaceutical Co., Ltd.

• A Study of ONO-7429 in Participants With Unresectable Advanced or Recurrent Solid TumorsRecruitingNCT07787208Phase 1

  Sponsor listed in the registry: Ono Pharmaceutical Co., Ltd.

• Study of DCC-2812 in Participants With Advanced Genitourinary CancersRecruitingNCT06966024Phase 1

  Sponsor listed in the registry: Deciphera Pharmaceuticals, LLC · First submitted after Deciphera Pharmaceuticals, LLC became part of Ono Pharmaceutical Co. Ltd

• Study to ONO-4538 in Patients With Rhabdoid TumorRecruitingNCT06622941Phase 2

  Sponsor listed in the registry: Ono Pharmaceutical Co., Ltd.

• MOVE: Tenosynovial Giant Cell Tumor (TGCT) Real-World Participant Experience With VimseltinibRecruitingNCT07075471

  Sponsor listed in the registry: Deciphera Pharmaceuticals, LLC · First submitted after Deciphera Pharmaceuticals, LLC became part of Ono Pharmaceutical Co. Ltd

• Study of DCC-2618 in Patients With GIST After at Least 3 Prior TreatmentsRecruitingNCT07618377Phase 1

  Sponsor listed in the registry: Ono Pharmaceutical Co., Ltd.

• A Study to Evaluate the Safety and Efficacy of Two Dose Levels of ONO-4578 With Opdivo®, in Combination With mFOLFOX6 and Bevacizumab Versus Standard of Care in Participants With Non-MSI-H/dMMR, PD-L1 Positive Advanced Colorectal CancerRecruitingNCT06948448Phase 2

  Sponsor listed in the registry: Ono Pharmaceutical Co., Ltd.

• A Study of ONO-3310 in Healthy Adult Male Subjects and Chronic Kidney Disease Patients With Type 2 Diabetes MellitusRecruitingNCT07619157Phase 1

  Sponsor listed in the registry: Ono Pharmaceutical Co., Ltd.

• A Retrospective Observational Study of Nivolumab in Combination With Chemotherapy as Neoadjuvant Therapy for Resectable NSCLC Patients: Real-World Experience in Taiwan (NEOREAL)RecruitingNCT07169708

  Sponsor listed in the registry: Ono Pharmaceutical Co., Ltd.

• ONO-4538 Study in Patients With Richter's TransformationRecruitingNCT06936943Phase 2

  Sponsor listed in the registry: Ono Pharmaceutical Co., Ltd.

• A Master Protocol to Evaluate DCC-3009 in Gastrointestinal Stromal Tumor (GIST)RecruitingNCT06630234Phase 1/2

  Sponsor listed in the registry: Deciphera Pharmaceuticals, LLC · First submitted after Deciphera Pharmaceuticals, LLC became part of Ono Pharmaceutical Co. Ltd

• A Study to Evaluate Vimseltinib in Adults With Active Chronic Graft-Versus-Host Disease (cGVHD)RecruitingNCT06619561Phase 2

  Sponsor listed in the registry: Deciphera Pharmaceuticals, LLC · First submitted after Deciphera Pharmaceuticals, LLC became part of Ono Pharmaceutical Co. Ltd

• ONO-2017 Study Japanese Patients With Primary Generalized Tonic Clonic Seizures.RecruitingNCT06579573Phase 3
• Safety of Cenobamate in Japanese Subjects With Partial Onset SeizuresRecruitingNCT06590896Phase 2
• Study of ONO-4578 and XELOX/FOLFOX Plus Bevacizumab in Colorectal CancerActive, not recruitingNCT06547385Phase 1

  Sponsor listed in the registry: Ono Pharmaceutical Co., Ltd.

• A Study of ONO-2020 in Participants With Mild to Moderate Alzheimer's DiseaseCompletedNCT06881836Phase 2

  Sponsor listed in the registry: Ono Pharmaceutical Co., Ltd.

• A Study of Inlexisertib (DCC-3116) in Combination With Anticancer Therapies in Participants With Advanced MalignanciesActive, not recruitingNCT05957367Phase 1/2

  Sponsor listed in the registry: Deciphera Pharmaceuticals, LLC · First submitted before Deciphera Pharmaceuticals, LLC became part of Ono Pharmaceutical Co. Ltd

• An Open-label, Uncontrolled Study of ONO-4578 and ONO-4538 in Combination With Standard-of-care Docetaxel and Ramucirumab as Second-line Therapy in Patients With Advanced or Recurrent Non-small Cell Lung CancerCompletedNCT06542731Phase 1

  Sponsor listed in the registry: Ono Pharmaceutical Co., Ltd.

• A Study of Ripretinib vs Sunitinib in Advanced GIST Patients After Treatment With ImatinibActive, not recruitingNCT03673501Phase 3

  Sponsor listed in the registry: Deciphera Pharmaceuticals, LLC · First submitted before Deciphera Pharmaceuticals, LLC became part of Ono Pharmaceutical Co. Ltd

• Evaluate the Effect of Vimseltinib on Pharmacokinetics of Combined Oral Contraceptive (Ethinyl Estradiol/Levonorgestrel)CompletedNCT07539090Phase 1

  Sponsor listed in the registry: Deciphera Pharmaceuticals, LLC · First submitted after Deciphera Pharmaceuticals, LLC became part of Ono Pharmaceutical Co. Ltd

• A Phase I Study of ONO-4538HSC in Subjects With Advanced or Metastatic Solid TumorsActive, not recruitingNCT06548217Phase 1

  Sponsor listed in the registry: Ono Pharmaceutical Co., Ltd.

• An Open-label, Uncontrolled Study of ONO-7913 and ONO-4538 in Combination With Modified FOLFIRINOX Therapy, the Standard of Care, as First-line Treatment in Patients With Metastatic Pancreatic CancerActive, not recruitingNCT06532344Phase 1

  Sponsor listed in the registry: Ono Pharmaceutical Co., Ltd.

• The Study of ONO-7913, ONO-4538 and the Standard of Care as First-line Treatment in Patients Colorectal CancerActive, not recruitingNCT06540261Phase 1

  Sponsor listed in the registry: Ono Pharmaceutical Co., Ltd.

• A PhaseⅠStudy of ONO-7475 in Combination With ONO-4538 and Gemcitabine Plus Nab-paclitaxel (GnP), the Standard of Care, and ONO-7475 in Combination With GnP in Patients With Pancreatic CancerActive, not recruitingNCT06532331Phase 1

  Sponsor listed in the registry: Ono Pharmaceutical Co., Ltd.

• A Phase 2 Study of ONO-2808 in Patients With Multiple System AtrophyActive, not recruitingNCT05923866Phase 2

  Sponsor listed in the registry: Ono Pharmaceutical Co., Ltd.

• Phase I Study Evaluating Tolerability, Safety, Pharmacokinetics, and Efficacy of Combined ONO-4059 and R-MPV Therapy for PCNSLActive, not recruitingNCT06541665Phase 1

  Sponsor listed in the registry: Ono Pharmaceutical Co., Ltd.

• Study of ONO-4685 in Patients With Relapsed or Refractory T Cell LymphomaActive, not recruitingNCT05079282Phase 1

  Sponsor listed in the registry: Ono Pharmaceutical Co., Ltd.

• A Phase I Study to Investigate the Tolerability and Safety of ONO-4685 Given as Monotherapy in T Cell Lymphoma and CLL/SLLActive, not recruitingNCT06547528Phase 1

  Sponsor listed in the registry: Ono Pharmaceutical Co., Ltd.

• Study of ONO-4578 With and Without ONO-4538 in Subjects Advanced or Metastatic Solid TumorsActive, not recruitingNCT03155061Phase 1

  Sponsor listed in the registry: Ono Pharmaceutical Co., Ltd.

• A Study of ONO-7428 in Participants With Unresectable Advanced or Recurrent Solid TumorsActive, not recruitingNCT06816108Phase 1

  Sponsor listed in the registry: Ono Pharmaceutical Co., Ltd.

• A Study of ONO-7018 in Patients With Relapsed or Refractory Non-Hodgkin LymphomaTerminatedNCT06622226Phase 1

  Sponsor listed in the registry: Ono Pharmaceutical Co., Ltd.

• ONO-4059 Study in Patients With Steroid-resistant PemphigusActive, not recruitingNCT06696716Phase 3

  Sponsor listed in the registry: Ono Pharmaceutical Co., Ltd.

• A Study of ONO-1110 in Patients With Postherpetic NeuralgiaCompletedNCT06708416Phase 2

  Sponsor listed in the registry: Ono Pharmaceutical Co., Ltd.

• A Study of ONO-1110 in Patients With Social Anxiety DisorderCompletedNCT06805565Phase 2

  Sponsor listed in the registry: Ono Pharmaceutical Co., Ltd.

• A Study of ONO-1110 in Patients With Major Depressive DisorderCompletedNCT06792136Phase 2

  Sponsor listed in the registry: Ono Pharmaceutical Co., Ltd.

• A Clinical Study of ONO-1110 in Patients With FibromyalgiaCompletedNCT06752590Phase 2

  Sponsor listed in the registry: Ono Pharmaceutical Co., Ltd.

• A Clinical Study of ONO-1110 in Patients With Hunner Type Interstitial CystitisCompletedNCT06752603Phase 2

  Sponsor listed in the registry: Ono Pharmaceutical Co., Ltd.

• A Study to Investigate the Pharmacokinetics of Tirabrutinib in Participants With Mild, Moderate, and Severe Hepatic Impairment Compared to Healthy ParticipantsCompletedNCT07198087Phase 1

  Sponsor listed in the registry: Ono Pharmaceutical Co., Ltd.

• Study of Vimseltinib (DCC-3014) in Patients With Advanced Tumors and Tenosynovial Giant Cell TumorActive, not recruitingNCT03069469Phase 1/2

  Sponsor listed in the registry: Deciphera Pharmaceuticals, LLC · First submitted before Deciphera Pharmaceuticals, LLC became part of Ono Pharmaceutical Co. Ltd