Drug
Simendan clinical trials
Also written Simdax and ODM-109.
- studies test it
- 75
- open now
- 5
- in phase 3
- 24
- first study started
- 2002
Keep track of what changes. Save the Simendan studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
75 studies that test it; most in 2009 (7)
| Year | Studies |
|---|---|
| 2002 | 2 |
| 2003 | 1 |
| 2004 | 2 |
| 2005 | 4 |
| 2006 | 2 |
| 2007 | 2 |
| 2008 | 2 |
| 2009 | 7 |
| 2010 | 3 |
| 2011 | 6 |
| 2012 | 3 |
| 2013 | 2 |
| 2014 | 4 |
| 2015 | 3 |
| 2016 | 1 |
| 2017 | 2 |
| 2018 | 6 |
| 2019 | 5 |
| 2020 | 5 |
| 2021 | 5 |
| 2022 | 1 |
| 2023 | 5 |
| 2025 | 2 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 1
- Phase 2
- 22
- Phase 3
- 24
- Phase 4
- 30
- No phase
- 5
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 13 · Other 62
Orion Corporation, Orion Pharma (7) · Assistance Publique - Hôpitaux de Paris (4) · Tenax Therapeutics, Inc. (3) · Sahlgrenska University Hospital (3) · Ain Shams University (2) · Göteborg University (2) · Tampere University Hospital (2) · University Medical Center Nijmegen (2)
Often tested with
Tested in the same studies.
Dobutamine (5) · Milrinone (4) · Magnesium Sulfate (1) · Epinephrine (1) · Norepinephrine (1)
Studies
Open first, then newest update. How each study uses Simendan is read from its arms, and is right about nine times in ten.
Testing it · 75
- Shorter Weaning From Invasive Ventilation With LevosimendanRecruitingPhase 4Radboud University Medical CenterNCT07105202Written as levosimendan
- Levosimendan in Acute Decompensated Heart FailureNot yet recruitingPhase 2/3Chittagong Medical CollegeNCT07262723Written as Levosimendan
- Effect of Early Use of Levosimendan Versus Placebo on Top of a Conventional Strategy of Inotrope Use on a Combined Morbidity-mortality Endpoint in Patients With Cardiogenic ShockRecruitingPhase 3Pr Bruno LEVYNCT04020263Written as Levosimendan 2.5 MG/ML Injectable Solution
- RCT Study of Levosimendan Improving Prognosis of Cardiac ArrestNot yet recruitingPhase 4Peking University Third HospitalNCT05956431Written as Levosimendan Injection
- Using TEE to Evaluate the Effect of Levosimendan on Patients With ARDS Associated With RVD During MVNot yet recruitingPhase 2/3Wuhan Union Hospital, ChinaNCT05768230Written as levosimendan
- Interest of Levosimendan in Reducing Weaning Failures of ExtraCorporeal Life Support - ECLSTerminatedPhase 3Centre Hospitalier Universitaire DijonNCT04158674Written as Levosimendan
- Clinical Outcomes of Levosimendan Versus Dobutamine Versus Milrinone in Cases With Acute Decompensated Heart Failure With Impaired Renal FunctionCompletedPhase 4Ain Shams UniversityNCT07186062Written as Levosimendan
- Levosimendan as Treatment of Aneurysmal SubArachnoid HaemorrhageCompletedPhase 2Assistance Publique - Hôpitaux de ParisNCT05664191Written as Levosimendan
- Levosimendan in Acute Kidney Injury StudyCompletedPhase 2/3VieCuri Medical CentreNCT01720030Written as Levosimendan
- Open-Label Rollover Study of Levosimendan in PH-HFpEF PatientsCompletedPhase 2Tenax Therapeutics, Inc.NCT03624010Written as Levosimendan
- Levosimendan In Ambulatory Heart Failure PatientsTerminatedPhase 4Medical University of BialystokNCT04705337Written as Levosimendan
- Effect Levosimendan Administration on Postoperative NT-proBNP in Cardiac Risk PatientsCompletedPhase 3Medical University of ViennaNCT04329624Written as Levosimendan
- LEVOSIMENDAN to Facilitate Weaning From ECMO in Severe Cardiogenic Shock PatientsCompletedPhase 3Assistance Publique - Hôpitaux de ParisNCT04728932Written as Levosimendan
- Hemodynamic Evaluation of Levosimendan in Patients With PH-HFpEFCompletedPhase 2Tenax Therapeutics, Inc.NCT03541603Written as Levosimendan
- Is Levosimendan Superior to Milrinone Regarding Acute Kidney Injury After Cardiac Surgery for Congenital Heart Disease?CompletedPhase 2Göteborg UniversityNCT02232399Written as Levosimendan
- Levosimendan Versus Combination With Magnesium Sulphate on Spine Protection by NIRS in Infants Undergoing CoarctectomyCompletedPhase 4Dalia Saad Abd-El KaderNCT04330755Written as Levosimendan
- Levosimendan Versus Placebo Before Tricuspid Valve Surgery in Patients With Right Ventricular DysfunctionStatus unknownPhase 3Assistance Publique - Hôpitaux de ParisNCT05233202Written as Levosimendan
- Effects of Oral Levosimendan on Respiratory Function in Patients With Amyotrophic Lateral Sclerosis (ALS): Open-Label ExtensionTerminatedPhase 3Orion Corporation, Orion PharmaNCT03948178Written as Levosimendan
- Acute and Chronic Protective Effects of Peri-interventional Administration of Levosimendan in ST Elevation Myocardial InfarctionsWithdrawnNot applicableRWTH Aachen UniversityNCT03022877Written as Levosimendan
- Effects of Oral Levosimendan (ODM-109) on Respiratory Function in Patients With ALSCompletedPhase 3Orion Corporation, Orion PharmaNCT03505021Written as Levosimendan
See all 75 studies that test Simendan →
As the comparator · 2 — what is tested is compared with Simendan
- Artificial Voice Analysis and Telemonitoring for Heart Failure. A Feasibility StudyRecruitingNot applicableNiguarda HospitalNCT07664748Written as Levosimendan
- A Clinical Study on Levosimendan Improvement of Prognosis of ARDS Patients by Optimizing Pulmonary HemodynamicsStatus unknownPhase 3Shenzhen Second People's HospitalNCT04020003Written as Levosimendan
Codes
What other systems call Simendan · ClinicalTrials.gg INT006729
- MeSH (NLM) D000077464SimendanConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 349552KRHKSIMENDANConfirmed FDA, NLM, Wikidata
- Wikidata Q27256351simendanConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C87689SimendanOne source FDA
- DrugBank DB12286One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000077464 | Simendan | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 349552KRHK | SIMENDAN | Confirmed FDA, NLM, Wikidata |
| Wikidata | Q27256351 | simendan | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C87689 | Simendan | One source FDA |
| DrugBank | DB12286 | — | One source Wikidata |
Also registered as levosimendan (UNII C6T4514L4E · RxNorm 73107).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.