Drug
Bosentan clinical trials
Also written Tracleer, Ro 47-0203 and ACT-050088.
- studies test it
- 86
- open now
- 4
- in phase 3
- 27
- first study started
- 2001
Keep track of what changes. Save the Bosentan studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
86 studies that test it; most in 2011 (12)
| Year | Studies |
|---|---|
| 2001 | 1 |
| 2003 | 5 |
| 2004 | 4 |
| 2005 | 5 |
| 2006 | 11 |
| 2007 | 6 |
| 2008 | 7 |
| 2009 | 5 |
| 2010 | 6 |
| 2011 | 12 |
| 2012 | 1 |
| 2013 | 4 |
| 2014 | 1 |
| 2015 | 3 |
| 2016 | 2 |
| 2017 | 1 |
| 2018 | 2 |
| 2019 | 1 |
| 2021 | 3 |
| 2023 | 1 |
| 2024 | 1 |
| 2025 | 2 |
| 2026 | 2 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 1
- Phase 1
- 17
- Phase 2
- 26
- Phase 3
- 27
- Phase 4
- 15
- No phase
- 7
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 38 · Other 48
Actelion (26) · Boehringer Ingelheim (4) · Assistance Publique - Hôpitaux de Paris (3) · University Hospital, Grenoble (2) · Radboud University Medical Center (2) · Medical University of Vienna (2) · Augusta University (1) · PharmaMar (1)
Often tested with
Tested in the same studies.
Sildenafil (3) · Ambrisentan (2) · Zongertinib (1) · BI 425809 (1) · Nerandomilast (1) · PM 01183 (1) · Zamicastat (1) · Imatinib (1)
Studies
Open first, then newest update. How each study uses Bosentan is read from its arms, and is right about nine times in ten.
Testing it · 86
- Bosentan in the Treatment of Giant Cell ArteritisNot yet recruitingPhase 2Assistance Publique - Hôpitaux de ParisNCT06957002Written as Bosentan
- Endothelin-1 Receptor Blockade in Resistant HypertensionRecruitingPhase 2University Hospital, RouenNCT04388124Written as Bosentan
- Dapagliflozin and Endothelin Receptor Antagonism in Large Vessel Vasculitis (DERAIL-LVV)RecruitingPhase 2University of EdinburghNCT06887062Written as Bosentan and dapagliflozin
- ENDOTHELION Study Group: Effect of Bosentan in NAION PatientsRecruitingPhase 3University Hospital, GrenobleNCT02377271Written as bosentan
- A Study in Healthy Men to Test How Bosentan Influences the Amount of Zongertinib in the BloodCompletedPhase 1Boehringer IngelheimNCT07649941Written as Bosentan
- Gemcitabine, Nab-Paclitaxel, and Bosentan for the Treatment of Unresectable Pancreatic CancerSuspendedPhase 1City of Hope Medical CenterNCT04158635Written as Bosentan
- Pulmonary Artery Remodelling With BosentanCompletedPhase 4ActelionNCT00595049Written as bosentan
- Bosentan in Systemic SclerosisCompletedPhase 4ActelionNCT01395732Written as Bosentan
- Effect of Bosentan in Patients With Metastatic Melanoma Treated With Dacarbazine (DTIC)CompletedPhase 2ActelionNCT01009177Written as Bosentan
- Effect of Bosentan in Scleroderma Renal CrisisCompletedPhase 2Assistance Publique - Hôpitaux de ParisNCT01241383Written as Bosentan
- A Study in Healthy Men to Test Whether Bosentan Influences the Amount of BI 425809 in the BloodCompletedPhase 1Boehringer IngelheimNCT05723874Written as Bosentan
- Preventive Effects of Bosentan on the Systemic Cardiovascular Consequence of Sleep ApneaCompletedPhase 2University Hospital, GrenobleNCT00777985Written as bosentan
- A Study in Healthy Men to Test How Bosentan Influences the Amount of Nerandomilast in the BloodCompletedPhase 1Boehringer IngelheimNCT07081932Written as Bosentan
- Study to Evaluate the Effect of Bosentan on the Pharmacokinetics of Lurbinectedin in Patients With Advanced Solid TumorsCompletedPhase 1PharmaMarNCT05072106Written as Bosentan
- FUTURE 3 Study ExtensionCompletedPhase 3ActelionNCT01338415Written as Bosentan
- Bosentan in Children With Pulmonary Arterial Hypertension Extension StudyCompletedPhase 3ActelionNCT00319020Written as Bosentan
- Combination Therapy in Pulmonary Arterial HypertensionCompletedPhase 4ActelionNCT00433329Written as Bosentan
- Effects of Tracleer (Bosentan) on Pulmonary Arterial Hypertension Related to Eisenmenger PhysiologyCompletedPhase 4ActelionNCT00317486Written as bosentan
- Bosentan in Digital UlcersCompletedPhase 3ActelionNCT00319696Written as Bosentan 62.5 mg
- Effects of Two Dosing Regimens of Bosentan in Children With Pulmonary Arterial HypertensionCompletedPhase 3ActelionNCT01223352Written as bosentan
See all 86 studies that test Bosentan →
Given in every arm · 5 — Bosentan is usual care beside what is tested
- A Clinical Trial to Evaluate MK-4208/Embibatinib in Healthy Adult Participants (MK-4208-001/Embibatinib-1014)CompletedPhase 1Terns, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)NCT07838987Written as Bosentan
- The "VISION" Trial: Ventavis Inhalation With Sildenafil to Improve and Optimize Pulmonary Arterial HypertensionTerminatedPhase 3ActelionNCT00302211Written as Bosentan
- Assess the Efficacy and Safety of Sildenafil When Added to Bosentan in the Treatment of Pulmonary Arterial HypertensionCompletedPhase 4Pfizer's Upjohn has merged with Mylan to form Viatris Inc.NCT00323297Written as Bosentan
- Role of Endothelin-A (ETA) and Endothelin-B (ETB) Receptors in the Vasodilatory Response to Endothelin-3 (ET-3)CompletedEarly Phase 1University of EdinburghNCT01100736Written as Bosentan
- Study of the Initial Combination of Bosentan With Iloprost in the Treatment of Pulmonary Hypertension PatientsStatus unknownPhase 3Air Force Military Medical University, ChinaNCT01712997Written as Bosentan
Codes
What other systems call Bosentan · ClinicalTrials.gg INT006693
- MeSH (NLM) D000077300BosentanConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) Q326023R30BOSENTANConfirmed FDA, NLM, Wikidata
- RxNorm 75207Confirmed FDA, Wikidata
- Wikidata Q27114267bosentan hydrateConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C47417BosentanConfirmed FDA, Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000077300 | Bosentan | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | Q326023R30 | BOSENTAN | Confirmed FDA, NLM, Wikidata |
| RxNorm | 75207 | — | Confirmed FDA, Wikidata |
| Wikidata | Q27114267 | bosentan hydrate | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C47417 | Bosentan | Confirmed FDA, Wikidata |
Also registered as bosentan anhydrous (UNII XUL93R30K2 · RxNorm 1468845).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.