Drug
Saline Solution clinical trials
Also written Normal saline and saline solution.
- studies test it
- 110
- open now
- 11
- in phase 3
- 14
- first study started
- 1999
Keep track of what changes. Save the Saline Solution studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
110 studies that test it; most in 2017 (9)
| Year | Studies |
|---|---|
| 1999 | 1 |
| 2002 | 1 |
| 2005 | 1 |
| 2007 | 4 |
| 2008 | 6 |
| 2009 | 7 |
| 2010 | 4 |
| 2011 | 5 |
| 2012 | 6 |
| 2013 | 4 |
| 2014 | 5 |
| 2015 | 8 |
| 2016 | 7 |
| 2017 | 9 |
| 2018 | 3 |
| 2019 | 3 |
| 2020 | 9 |
| 2021 | 5 |
| 2022 | 5 |
| 2023 | 5 |
| 2024 | 5 |
| 2025 | 2 |
| 2026 | 5 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 8
- Phase 1
- 14
- Phase 2
- 19
- Phase 3
- 14
- Phase 4
- 25
- No phase
- 41
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 4 · Other 106
Vanderbilt University Medical Center (3) · University of Alberta (2) · Columbia University (2) · University of Pittsburgh (2) · The University of Texas Health Science Center at San Antonio (2) · IRCCS Burlo Garofolo (2) · University of Arkansas (2) · Assiut University (2)
Often tested with
Tested in the same studies.
Ropivacaine (5) · Botulinum toxin type A (3) · Ringer's Lactate (3) · Dexamethasone (3) · Soybean oil, phospholipid emulsion (2) · Lidocaine (2) · Exenatide (2) · Olanzapine (1)
Studies
Open first, then newest update. How each study uses Saline Solution is read from its arms, and is right about nine times in ten.
Testing it · 110
- Magnesium Sulfate With Standard Combined Costoclavicular-Suprascapular Block for Pain Relief After Shoulder Arthroscopy.Not yet recruitingNot applicableAssiut UniversityNCT07798115Written as Normal Saline (NS)
- Corticosteroid Against Saline Injections for Thumb Osteoarthritis (CASITOA)RecruitingPhase 2Université du Québec à Trois-RivièresNCT06401317Written as Saline Solution (NaCl 0,9%)
- Perineural vs Intravenous Dexamethasone as an Adjuvant to Brachial Plexus Block in Pediatric Hand SurgeryRecruitingNot applicablePoznan University of Medical SciencesNCT07474909Written as 0.9%NaCl
- Flush, Lyse, OperateNot yet recruitingPhase 4Dartmouth-Hitchcock Medical CenterNCT07592520Written as Intrapleural Saline with possible escalation to intraplerual alteplase and dornase.
- Normal Saline Infusion After Intravenous Thrombolysis in StrokeNot yet recruitingPhase 3Tianjin Medical University General HospitalNCT07497542Written as normal saline
- Genetic Architecture of Natriuretic Peptides and Blood Pressure ResponseNot yet recruitingNot applicableUniversity of Alabama at BirminghamNCT07118592Written as Saline Infusion
- Trial of IV vs Oral Iron Treatment of Iron Deficiency Anemia in the Post-Operative Bariatric Surgical PatientRecruitingPhase 3Auerbach Hematology Oncology Associates P CNCT04268849Written as Saline
- Effect of Nasal Spray Dexmedetomidine on Emergence Delirium Prevention in Total Hip ReplacementRecruitingPhase 4Second Affiliated Hospital, School of Medicine, Zhejiang UniversityNCT06579001Written as Nasal spray dexmedetomidine
- Effect of Fluid Resuscitation on Lactate in Traumatic Injury PatientsNot yet recruitingPhase 1/2Assiut UniversityNCT06370975Written as 0.9% Normal saline
- Evaluation of Blood Sampling From a Pre-existed Peripheral Intravenous Catheter LineRecruitingPhase 4Imam Abdulrahman Bin Faisal UniversityNCT05543772Written as Normal saline
- Botox Vs Spinal Cord Stimulation in the Treatment of Refractory Migraine Clinical TrialNot yet recruitingNot applicableEuropainclinics z.ú.NCT05382832Written as SCS
- Intravenous (IV) Saline and Exercise in Postural Tachycardia Syndrome (POTS)Active, not recruitingNot applicableVanderbilt University Medical CenterNCT01000350Written as Saline
- Effects of Antipsychotics on Brain Insulin Action in FemalesActive, not recruitingNot applicableCentre for Addiction and Mental HealthNCT06251635Written as Saline
- Renal Anhydramnios Fetal TherapyCompletedPhase 1Johns Hopkins UniversityNCT03101891Written as Isotonic fluid
- Outcome of Treatment With Botulinum toxinA in Patients With Temporomandibular Myofascial PainCompletedPhase 4PAEC General Hospital, IslamabadNCT07668375Written as Normal Saline
- Study of Mesenchymal Autologous Stem Cells as Regenerative Treatment for Multiple SclerosisActive, not recruitingPhase 1/2Haukeland University HospitalNCT04749667Written as Saline
- Intravenous Fluid for Pediatric Migraine in the Emergency DepartmentCompletedPhase 1/2University of AlbertaNCT01073787Written as Normal saline
- Effect of Different Modalities of Cryotherapy on Post-Operative Pain in Patients With Symptomatic Irreversible PulpitisCompletedNot applicableOctober 6 UniversityNCT06304259Written as Saline
- Corticosteroid Effects on Asymptomatic Gadolinium-enhancing Lesions in Multiple SclerosisCompletedPhase 2Mazandaran University of Medical SciencesNCT04979650Written as Normal saline
- A Phase I Study to Evaluate the Safety and Drug Allergy of HLB3-002 in Healthy VolunteersCompletedPhase 1Huonslab Co., Ltd.NCT06713317Written as 0.9% NaCl
See all 110 studies that test Saline Solution →
Given in every arm · 120 — Saline Solution is usual care beside what is tested
- Effect of Preoperative Intranasal Dexmedetomidine on Incidence of Intraoperative Shivering in Patients Undergoing Cesarean Section Under Spinal AnesthesiaNot yet recruitingPhase 4Assiut UniversityNCT07855536Written as Normal Saline 0.9%
- RM1 Project 1 - tAN NaloxoneRecruitingEarly Phase 1Medical University of South CarolinaNCT05490134Written as Saline
- Reversing Glucose and Lipid-mediated Vascular DysfunctionRecruitingEarly Phase 1University of Kansas Medical CenterNCT04832009Written as Saline
- Brain Tumor Surgery and Postoperative DeliriumNot yet recruitingNot applicableKaohsiung Medical University Chung-Ho Memorial HospitalNCT06863064Written as Normal Saline
- Comparsion of Intravenous Injection of Magnesium Sulfate and Lidocaine Effectiveness on the Prevention of Laryngospasm and Analgesic Requirement in TonsillectomyNot yet recruitingPhase 3Assiut UniversityNCT06761547Written as Saline
- Allopurinol and Trimetazidine as a Preventive of Acute Kidney Injury in PCI PatientsRecruitingPhase 4Beni-Suef UniversityNCT05540184Written as Normal saline
- Effect on QTc, Pharmacokinetics, Safety, and Preliminary Efficacy of Single-agent Palifosfamide-tris in Subjects With Advanced Solid TumorsCompletedPhase 1Alaunos TherapeuticsNCT01340547Written as Normal Saline
- The Suppression of Toll Like Receptors by InsulinCompletedNot applicableUniversity at BuffaloNCT01151605Written as Saline Infusion
- Gastric CLEANsing by Intravenous AZithromycin in Urgent EndoscopyCompletedNot applicableClinical Hospital ColentinaNCT06077916Written as Saline solution
- Effects of Ghrelin Administration on MotivationCompletedNot applicableUniversity Hospital TuebingenNCT06576440Written as Saline
- Utility of Liposomal Bupivacaine Transversus Abdominal Plane Block for Open MyomectomyCompletedPhase 4Icahn School of Medicine at Mount SinaiNCT04272086Written as normal saline
- ZIKA Vaccine in Naive SubjectsCompletedPhase 1National Institute of Allergy and Infectious Diseases (NIAID)NCT02952833Written as Saline
- 2 Dose Neuraxial Morphine for Prevention of PDPHCompletedPhase 4Columbia UniversityNCT02473276Written as Sterile normal saline
- Substance P Challenge in Healthy ParticipantsCompletedNot applicableGlaxoSmithKlineNCT04676763Written as Normal Saline
- Effects of Niacin on Intramyocellular Fatty Acid Trafficking in Upper Body Obesity and Type 2 Diabetes MellitusCompletedEarly Phase 1Mayo ClinicNCT03867500Written as Saline
- Sex Differences in Risk for Alcohol AbuseCompletedNot applicableMark FillmoreNCT04543942Written as Saline
- Using Vasopressor Medication to Support Blood Pressure During Intubation ProcedureCompletedPhase 3Wright State UniversityNCT05355974Written as normal saline
- Skin Irritation Potential of MOB015B in Healthy Subjects Using a Cumulative Irritant Patch Test DesignCompletedPhase 1Moberg Pharma ABNCT06369675Written as 0.9% Saline
- Erector Spinae Plane Block Versus Intercostal for VATSCompletedNot applicableMcGill University Health Centre/Research Institute of the McGill University Health CentreNCT03902782Written as Normal saline
- Depomedrol for Genicular Nerve Block.CompletedNot applicableMenoufia UniversityNCT05893771Written as normal saline
Showing 20 of 120.
As the comparator · 33 — what is tested is compared with Saline Solution
- Perioperative Dezocine Administration and Postoperative Delirium in Elderly Cardiac Surgery PatientsNot yet recruitingNot applicableChinese Academy of Medical Sciences, Fuwai HospitalNCT07768150Written as Normal Saline (NS)
- Wound Irrigation With Saline Versus Hypodilute-chlorhexidine After Cesarean Section (WISHES Study)RecruitingNot applicableLoma Linda UniversityNCT06339203Written as Normal Saline
- Study on the Improvement of Microcirculation in Patients With Sepsis by Vitamin B6, Vitamin B12 and Vitamin CRecruitingNot applicableFan ZengNCT06749756Written as 0.9%Nacl
- Nasal Irrigation With Combination of 0.9% NaCl and Binahong Extract (Anredera Cordifolia) 2,5% In Allergic RhinitisEnrolling by invitationPhase 1Gadjah Mada UniversityNCT05960526Written as Isotonic saline nasal irrigation
- Auricular Acupuncture vs SOC in Migraine HARecruitingNot applicableUniversity of LouisvilleNCT02681211Written as Normal saline fluid bolus 20mL/kg, max 1000mL
- ATAPAC Study (TauroLock Activity in Adult Cancer Patients)CompletedNot applicableCentre Hospitalier Régional Metz-ThionvilleNCT02279121Written as saline solution
- Dexmedetomidine for ESPB in Pain Management After Pediatric Idiopathic Scoliosis SurgeryCompletedPhase 4Poznan University of Medical SciencesNCT06789016Written as 0.9%NaCl
- Peritoneal Lavage Using Saline or Saline With Ondansetron for Pain Control After Laparoscopic CholecystectomyActive, not recruitingPhase 4Instituto Mexicano del Seguro SocialNCT06632184Written as Saline Intraperitoneal Lavage
- Dexamethasone for ESPB in Total Hip ArthroplastyCompletedPhase 4Poznan University of Medical SciencesNCT06789042Written as 0.9%NaCl
- Ultrasound-Guided Injections for Meniscal Injuries in Active-Duty MilitaryCompletedPhase 2Kessler FoundationNCT04274543Written as Normal Saline
- Effect of Mild Sedation and Analgesia on Radial Artery Cannulation in Novice ResidentsCompletedNot applicableAffiliated Hospital of Jiaxing UniversityNCT05863455Written as control
- Ketamine Infusion in Neurologic DeficitCompletedPhase 2/3Unity Health TorontoNCT02636218Written as 0.9% NaCl
- Dexmedetomidine Infusion During Laparoscopic AdrenalectomyCompletedNot applicableYonsei UniversityNCT06037135Written as 0.9% normal saline
- Safety of N-acetylcysteine in Maternal Chorioamnionitis (NAC in Chorio)CompletedPhase 1/2Medical University of South CarolinaNCT00724594Written as Control
- Ketamine or Neostigmine for Serratus Anterior Plane Block in Modified Radical MastectomyCompletedNot applicableCairo UniversityNCT04544228Written as bupivacaine +saline
- Autologous Platelet-rich Plasma for Clomiphene Citrate-induced Thin EndometriumCompletedPhase 2/3Benha UniversityNCT03770026Written as Saline cervical flushing
- Hypertonic Saline for Fluid Resuscitation After Cardiac SurgeryCompletedPhase 4Insel Gruppe AG, University Hospital BernNCT03280745Written as 0.9% saline
- Saline Hypertonic in PreschoolersCompletedNot applicableUniversity of Washington, the Collaborative Health Studies Coordinating CenterNCT02378467Written as 0.9% Isotonic Saline (IS)
- IV Glucose for Dehydration TreatmentCompletedPhase 2Children's Hospital of PhiladelphiaNCT01285713Written as Normal Saline (NS)
- Hemostasis Evolution During Fluid Loading in Abdominal Surgery. Effects of Fluid Choice: Saline Versus Hydroxyethyl Starch (HAEMO Study)CompletedPhase 4University Hospital, Clermont-FerrandNCT03420261Written as 0.9% saline
Showing 20 of 33.
Codes
What other systems call Saline Solution · ClinicalTrials.gg INT006697
- NCI Thesaurus C821SalineOne source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| NCI Thesaurus | C821 | Saline | One source FDA |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.