Nephrotic Syndrome clinical trials
The registry lists 191 studies for Nephrotic Syndrome across more than 10 countries. 65 are recruiting or about to start. 127 of them are mainly about Nephrotic Syndrome (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
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Who runs them
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (11) · The Children's Hospital of Zhejiang University School of Medicine (11) · Assistance Publique - Hôpitaux de Paris (9) · Istituto Giannina Gaslini (7) · Mario Negri Institute for Pharmacological Research (6) · University of Michigan (5) · Children's Hospital of Fudan University (5) · Assiut University (4)
What is being tested here
Drugs under test in Nephrotic Syndrome studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Drug classes tested here Calcineurin inhibitors 2 open · Factor Xa inhibitors 1 open · Corticosteroids 6 · Statins 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 10, phase 3 first
- Feb 2027Ketoanalogues for Muscle Mass Loss in Nephrotic Syndrome · Phase 3 · Military Institute od Medicine National Research Institute
- Jun 2027Efficacy and Safety of Obinutuzumab Versus Rituximab in Childhood Steroid Dependant and Frequent Relapsing Nephrotic Syndrome · Phase 3 · Assistance Publique - Hôpitaux de Paris
- Dec 2026The Clinical Application Study of Obinutuzumab in Pediatric Refractory Nephrotic Syndrome · Children's Hospital of Chongqing Medical University
- Dec 2026SPL Insufficiency Syndrome (SPLIS)/NPHS14: a SPLIS Observational Study and Patient Registry (International) · University of California, San Francisco
- Dec 2026Steroid Diabetes in Patients With Kidney Disease · Zhejiang Provincial People's Hospital
- Jan 2027A Smart Phone Application to Improve Adoption of the 2024 Kidney Disease Improving Global Outcomes (KDIGO) Chronic Kidney Disease (CKD) Guidelines · St. James's Hospital, Ireland
- Jul 2027The Role of Proprotein-convertase-subtilisin/Kexin-type 9 in Kidney Damage in Nephrotic Syndrom · Kolding Sygehus
- Aug 2027Non-invasive Diagnosis of Idiopathic Nephrotic Syndromes · Assistance Publique - Hôpitaux de Paris
- Aug 2027Clinical Prediction Model for Disease Progression in Primary Membranous Nephropathy · Assiut University
- Nov 2027Atacicept in Multiple Glomerular Diseases · Vera Therapeutics, Inc.
Who these studies take
Of the 50 Nephrotic Syndrome studies recruiting now, 23 (46%) set no upper age limit and 22 (44%) stop at 75 or younger. 37 (74%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 4 (8%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 34 (68%) | 34 (68%) |
| 18 | 43 (86%) | 43 (86%) |
| 30 | 35 (70%) | 35 (70%) |
| 40 | 34 (68%) | 34 (68%) |
| 50 | 33 (66%) | 33 (66%) |
| 65 | 33 (66%) | 33 (66%) |
| 75 | 33 (66%) | 33 (66%) |
| 85 | 26 (52%) | 26 (52%) |
Across all 191 studies, recruiting or not: 59% stop at 75 or younger and 51% at 65; 68% take children; 0% are for women only and 0% for men only; 12% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 13, 2026.
Results posted1
Studies
Recruiting first, then most recently updated. Showing 50 of 191. Browse all 191 → or search them.
- Nephrotic Syndrome Study NetworkRecruitingNCT012090002 countries
- Effects of Meal Macronutrients on Postprandial LipidsNot yet recruitingNCT07313787Phase 21 country
- NEPTUNE Match StudyRecruitingNCT04571658Not applicable1 country
- Immune System Related Kidney DiseaseRecruitingNCT000019791 country
- Diuretic Tuner Clinical Decision SupportRecruitingNCT04759274Not applicable1 country
- Rituximab Plus Cyclosporine in Idiopathic Membranous NephropathyRecruitingNCT00977977Phase 21 country
- Clinical Phenotyping Resource and Biobank Core of the Michigan O'Brien Renal CenterEnrolling by invitationNCT010166131 country
- Belimumab With Rituximab for Primary Membranous NephropathyRecruitingNCT03949855Phase 21 country
- Super Chinese Nephrotic Syndrome Registration System (SUCCESS)RecruitingNCT030019341 country
- Single-cell RNA Sequencing (scRNA-seq) to Investigate the Mechanisms Underlying the Induction of Regulatory T Cells in Patients With Extramembranous Glomerulonephritis Treated With RituximabNot yet recruitingNCT07811557Not applicable1 country
- Clinical Prediction Model for Disease Progression in Primary Membranous NephropathyNot yet recruitingNCT07785739
- Zuberitamab in the First Episode of Paediatric Nephrotic SyndromeNot yet recruitingNCT07765914Phase 31 country
- Natural History of Sphingosine Phosphate Lyase Insufficiency Syndrome (SPLIS)RecruitingNCT066699491 country
- RD06-05 Universal CD19/BCMA CAR-T for Refractory Pediatric Autoimmune DiseasesNot yet recruitingNCT07674147Early Phase 11 country
- Atacicept in Multiple Glomerular DiseasesRecruitingNCT06983028Phase 21 country
- From Immune System Damage to Podocyte Cell Damage: Prospective Database and Biological Collection of Patients (Children and Adults) With MGLS and HSFPRecruitingNCT041740661 country
- SGLT2 Inhibitors in Adult Primary Nephrotic SyndromeRecruitingNCT07214818Phase 2/31 country
- CD19/BCMA UCAR-T for B Cell-Related Autoimmune DiseaseRecruitingNCT07586267Early Phase 11 country
- A Smart Phone Application to Improve Adoption of the 2024 Kidney Disease Improving Global Outcomes (KDIGO) Chronic Kidney Disease (CKD) GuidelinesRecruitingNCT07561957Not applicable1 country
- Allogeneic CD19/BCMA CAR-T for B Cell-Related Autoimmune DiseaseRecruitingNCT07507201Early Phase 11 country
- Multitarget Strategy for Primary PodocytopathiesRecruitingNCT06718894Not applicable1 country
- An Outcome Analysis of Primary Membranous NephropathyRecruitingNCT062423271 country
- A Study of the Safety, Tolerability, Pharmacokinetics and Efficacy of Treatment With AP1189 in Patients With iMN and Severe ProteinuriaRecruitingNCT04456816Phase 21 country
- A Study of Anti-CD38 Monoclonal Antibody (SG301) Subcutaneous Injection in Children With Nephrotic Syndrome With Frequent Relapses or Steroid DependenceRecruitingNCT07087314Phase 21 country
- CAR T-cell Therapy Targeting CD19 and BCMA in Patients With B Cell Mediated Autoimmune DiseaseRecruitingNCT07305116Phase 11 country
- Interview Study of Adult and Child Patients and Parents of Children With Swelling Due to Nephrotic Syndrome.RecruitingNCT055055001 country
- Dupilumab Therapy in Nephrotic Syndrome in ChildrenRecruitingNCT07091175Phase 21 country
- Anti-CD19/BCMA CAR-NK Cells in Patients With B Cell Mediated Autoimmune DiseaseRecruitingNCT06792799Early Phase 11 country
- SPL Insufficiency Syndrome (SPLIS)/NPHS14: a SPLIS Observational Study and Patient Registry (International)RecruitingNCT048851791 country
- The Role of Vitamin K2 in Preventing Glucocorticoid-Induced Bone Loss in Children With Nephrotic SyndromeRecruitingNCT07206537Not applicable1 country
- The FOrMe Registry (The German Focal Segmental Glomerulosclerosis and Minimal Change Disease Registry)RecruitingNCT039499721 country
- The Role of Proprotein-convertase-subtilisin/Kexin-type 9 in Kidney Damage in Nephrotic SyndromRecruitingNCT063739131 country
- Autoantibodies Against-nephrin in Idiopathic Nephrotic SyndromeRecruitingNCT063346921 country
- Study of Therapeutic Efficacy of CAR-T Cell Therapy in Patients With MDR-SRNSRecruitingNCT06553898Phase 11 country
- Non-invasive Diagnosis of Idiopathic Nephrotic SyndromesRecruitingNCT068208661 country
- Edoxaban Steady-State PK/PD in Adults With Nephrotic SyndromeNot yet recruitingNCT07116239Not applicable
- Blinatumomab for CNI-Resistant/Intolerant SRNS in ChildrenRecruitingNCT06607991Phase 11 country
- Study on the Efficacy and Safety of Fecal Microbiota Transplantation in the Treatment of Steroid - Dependent /Steroid-resistant Nephrotic Syndrome in ChildrenNot yet recruitingNCT07003438Early Phase 1
- Biomarkers and Outcome Predictors of Pediatric Nephrotic Syndrome: A Genetic, Transcriptomic, and Secretome Multiomics StudyNot yet recruitingNCT06792448
- Rituximab in the First Episode of Paediatric Nephrotic SyndromeNot yet recruitingNCT05850546Phase 31 country
- Cardiac Performance Evaluation in Children With Steroid Dependent vs Steroid Resistant Nephrotic SyndromeRecruitingNCT06622915Not applicable1 country
- Study of the Telitacicept in Pediatric Patients With Frequently Relapsing or Steroid Dependent Nephrotic SyndromeRecruitingNCT06125405Phase 31 country
- Clinical Follow-up Study of Rituximab in the Treatment of Nephrotic Syndrome in ChildrenRecruitingNCT065300041 country
- Electroencephalographic Changes in Nonconvulsive Children With Chronic Renal DiseaseNot yet recruitingNCT06185257
- The Efficacy and Safety of Prednisone Combined With Huaiqihuang Granule for Primary Nephrotic Syndrome in ChildrenRecruitingNCT05772871Phase 41 country
- Predictive Determinants of Nephrotic Syndrome Remission in Patients With At-risk Polymorphism of APOL1Not yet recruitingNCT064430341 country
- Effect of Sodium-glucose Cotransporter-2 Inhibitors (SGLT-2i) on Proteinuria in Nephrotic Children Older Than 10 YearsRecruitingNCT06417320Phase 41 country
- Rituximab, Cyclophosphamide, and Corticosteroids in Primary Membranous NephropathyRecruitingNCT05679336Not applicable1 country
- Steroid Diabetes in Patients With Kidney DiseaseRecruitingNCT061617011 country
- Efficacy and Safety of Rituximab Versus Mycophenolate Mofetil in Children With Steroid-dependent Nephrotic SyndromeRecruitingNCT05843968Phase 21 country