Prilocaine clinical trials
Also written Citanest.
Counted the way a researcher would: Prilocaine with its salts, dosage forms, brands and biosimilars. Looking for a trial to join? Including related medicines shows more you could take part in.
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How each study uses Prilocaine is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
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Approvals
The first approval found in each region, with its record
- United States
- 18 Nov 1965 · CITANEST PLAIN · NDA 014763 (FDA, Drugs@FDA)
- European Union
- 15 Nov 2013 · Fortacin · EMEA/H/C/002693 (EMA; in a combination)
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
How studies write it
Studies that test it under each name
Studies by the year they started
34 studies that test it; most in 2023 (6)
| Year | Studies |
|---|---|
| 2008 | 2 |
| 2009 | 2 |
| 2010 | 3 |
| 2011 | 1 |
| 2012 | 3 |
| 2015 | 2 |
| 2016 | 3 |
| 2017 | 2 |
| 2018 | 2 |
| 2019 | 1 |
| 2021 | 1 |
| 2022 | 1 |
| 2023 | 6 |
| 2024 | 4 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 1 · Other 33
National University Hospital, Singapore (2) · Cairo University (2) · Federal University of Minas Gerais (2) · CAMC Health System (1) · Helwan University (1) · Guy's and St Thomas' NHS Foundation Trust (1) · Theodor Bilharz Research Institute (1) · South Valley University (1)
Often tested with
Tested in the same studies.
Lidocaine (14) · Bupivacaine (9) · Ethyl Chloride (1) · Carticaine (1) · Epinephrine (1) · Felypressin (1) · Lidocaine, Prilocaine Drug Combination (1) · Remifentanil (1)
Related medicines
As reviewed, each with the page that says it.
- One of Local anesthetics source
Coming up
From the study records. Dates are the sponsors’ own estimates and often move.
Reaching primary completion within a year · 1
Studies that test Prilocaine.
- May 2027Spinal Anesthesia With Bupivacaine Versus Prilocaine on Postoperative Shivering After Inguinal Hernia RepairPhase 4 · Amr mohamed
Studies
Open first, then newest update. How each study uses Prilocaine is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 34
- Spinal Anesthesia With Bupivacaine Versus Prilocaine on Postoperative Shivering After Inguinal Hernia RepairNot yet recruitingPhase 4Amr mohamedNCT07564180Written as Prilocaine spinal anesthesia
- Pain Control in Pediatric Oncology: Utility of EMLA Cream vs Lidocaine Injection in Lumbar PuncturesCompletedPhase 4CAMC Health SystemNCT04003012Written as EMLA
- Intrathecal Injection of Hyperbaric Prilocaine Versus Hyperbaric Bupivacaine for Cystoscopic ProceduresCompletedNot applicableHelwan UniversityNCT07664618Written as Prilocaine
- Hyperbaric Prilocaine Compared With Hyperbaric Bupivacaine in Cervical Cerclage?CompletedPhase 4Guy's and St Thomas' NHS Foundation TrustNCT04394533Written as Prilocaine (Hyperbaric 2%)
- Hyperbaric Bupivacaine Versus Hyperbaric Prilocaine in Spinal AnaesthesiaActive, not recruitingPhase 4National University Hospital, SingaporeNCT07329582Written as prilocaine
- Unilateral Intrathecal Bupivacaine Versus Prilocaine on Postoperative Spontaneous VoidingCompletedPhase 4Theodor Bilharz Research InstituteNCT07262398Written as Prilocaine
- Effect of Prilocaine vs Bupivacaine on Hemodynamics in Spinal Anesthesia for Geriatric PatientsCompletedPhase 3Cairo UniversityNCT06165679Written as Prilocaine
- Comparing the Effect of Spinal Bupivacaine Versus Spinal Prilocaine on Maternal Blood Pressure in Cesarean SectionCompletedNot applicableSouth Valley UniversityNCT06290583Written as Prilocaine
- Comparison of Infraclavicular Brachial Plexus Block and Local Anesthesia in Arteriovenous Fistula Surgeries and Their Effects on Tissue Oxygen SaturationCompletedNot applicableAnkara City Hospital BilkentNCT06416111Written as Prilocaine
- Effect of Prilocaine on Motor Block During Caesarean SectionCompletedPhase 4Cairo UniversityNCT06133881Written as prilocaine
- Topical Anaesthesia in Cutaneous Head and Neck SurgeryCompletedNot applicableUniversity Hospital WaterfordNCT06274905Written as EMLA
- Selective Spinal Anaesthesia With Hyperbaric Prilocain With 2%Provides Better Perioperative Hemodynamic Stability for Patients With Peripheral Vascular Disease and Cardiac Dysfunction in Lower Limb SurgeryStatus unknownNot applicableAssiut UniversityNCT05877690Written as Prilocaine Hydrochloride 2% Injection
- Efficacy and Safety of Prilocaine 2% and Lidocaine 5% Hyperbaric Against Spinal Anesthesia in Post Cystoscopy ProcedureStatus unknownPhase 4Universitas Sebelas MaretNCT05834647Written as Prilocaine 2%
- Comparison of Hyperbaric Prilocaine 2% 50 Mg and Hyperbaric Bupivacaine 0.5% 12.5 Mg Against Spinal Anesthesia Recovery Time in Cystoscopy ProcedureStatus unknownPhase 4Indonesia UniversityNCT05610007Written as Prilocaine
- Spinal Prilocaine for Caesarian SectionsCompletedNot applicableUniversity Hospital, AntwerpNCT03219086Written as Prilocaine
- Pediatric Study to Access Pharmacokinetics and Safety of Oraqix GelCompletedPhase 4Dentsply InternationalNCT01591616Written as lidocaine and prilocaine
- Comparison of Articaine and Prilocaine for Extraction of Maxillary TeethCompletedPhase 4Taibah UniversityNCT04236115Written as Prilocain 3%
- Pain Perception During Vulvar BiopsyTerminatedPhase 4Duke UniversityNCT03654417Written as EMLA
- Local Anesthetic Cream in Younger Patients Undergoing Lumbar PuncturesCompletedPhase 2Wake Forest University Health SciencesNCT01516684Written as EMLA
- Jet Injection of 1% Buffered Lidocaine Versus Topical EMLA for Local Anesthesia Before Lumbar Puncture in ChildrenTerminatedNot applicableUniversity of Colorado, DenverNCT01628874Written as EMLA
See all 34 studies that test Prilocaine →
Given beside what is tested · 9 — Prilocaine is usual care or a partner of the new treatment
- Intraprostatic Anesthesia During Transperineal Prostate BiopsyActive, not recruitingNot applicableMarmara UniversityNCT07683182Written as Prilocaine
- Combined Adductor&Sciatic Nerve Block vs Femoral&Sciatic Nerve Block in Total Knee Replacement SurgeryCompletedNot applicableBakirkoy Dr. Sadi Konuk Research and Training HospitalNCT05648708Written as Bupivacaine and prilocaine hydrochloride
- Effect of Intrathecal Morphine on Urinary Bladder Function and Recovery in Patients Having a Cesarean DeliveryCompletedNot applicableUniversity of LiegeNCT05042817Written as 50 mg prilocaine + 2.5 mcg sufentanil
- Comparison of Infraclavicular And Supraclavicular BlockStatus unknownPhase 4Bozyaka Training and Research HospitalNCT04784104Written as Prilocaine HCl 2% Injectable solution
- Botulinum Toxin Type A Injection After Topical Anesthesia Versus Petrolatum OintmentCompletedPhase 4The University of Texas Health Science Center, HoustonNCT03799484Written as 2.5% lidocaine/2.5% prilocaine
- Decision Support for Intraoperative Low Blood PressureCompletedNot applicableVanderbilt University Medical CenterNCT02726620Written as Prilocaine
- Study of Fentanyl-Propofol-EMLA of L.M.X4 Technique for Bone Marrow AspirationTerminatedPhase 3St. Jude Children's Research HospitalNCT00187135Written as EMLA
- 7% Lidocaine/7% Tetracaine Cream Versus 2,5% Lidocaine / 2,5% Prilocaine CreamCompletedPhase 4Erasmus Medical CenterNCT02372786Written as 2,5% lidocaine / 2,5% prilocaine cream
- Ultrasound Guided Distal Sciatic Nerve Block - a Comparison With Nerve Stimulator TechniqueCompletedNot applicableHelios Research CenterNCT01643616Written as Prilocaine 1%
Codes
What other systems call Prilocaine · ClinicalTrials.gg INT008087
- MeSH (NLM) D011318PrilocaineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 046O35D44RPRILOCAINEConfirmed FDA, NLM, Wikidata
- RxNorm 8686Confirmed FDA, Wikidata
- Wikidata Q413598prilocaineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C47685PrilocaineOne source FDA
- DrugBank DB00750One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D011318 | Prilocaine | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 046O35D44R | PRILOCAINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 8686 | — | Confirmed FDA, Wikidata |
| Wikidata | Q413598 | prilocaine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C47685 | Prilocaine | One source FDA |
| DrugBank | DB00750 | — | One source Wikidata |
Also registered as prilocaine hydrochloride (UNII MJW015BAPH · RxNorm 2557).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.