Drug
Neostigmine clinical trials
- studies test it
- 82
- open now
- 7
- in phase 3
- 14
- first study started
- 1996
Keep track of what changes. Save the Neostigmine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Brand
Studies by the year they started
82 studies that test it; most in 2017 (10)
| Year | Studies |
|---|---|
| 1996 | 1 |
| 2006 | 1 |
| 2007 | 1 |
| 2008 | 2 |
| 2009 | 3 |
| 2010 | 1 |
| 2011 | 1 |
| 2012 | 3 |
| 2013 | 4 |
| 2014 | 5 |
| 2015 | 4 |
| 2016 | 2 |
| 2017 | 10 |
| 2018 | 5 |
| 2019 | 8 |
| 2020 | 3 |
| 2021 | 8 |
| 2022 | 3 |
| 2023 | 6 |
| 2024 | 7 |
| 2025 | 2 |
| 2026 | 2 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 4
- Phase 1
- 6
- Phase 2
- 13
- Phase 3
- 14
- Phase 4
- 35
- No phase
- 18
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 1 · Other 81
Assiut University (8) · Cairo University (5) · Ain Shams University (3) · James J. Peters Veterans Affairs Medical Center (3) · West Virginia University (2) · Alexandria University (2) · University of Texas Southwestern Medical Center (2) · Mansoura University (2)
Often tested with
Tested in the same studies.
Sugammadex (37) · Glycopyrrolate (16) · Atropine (8) · Dexmedetomidine (4) · Rocuronium (3) · Bupivacaine (3) · Magnesium Sulfate (2) · Cisatracurium (2)
Studies
Open first, then newest update. How each study uses Neostigmine is read from its arms, and is right about nine times in ten.
Testing it · 82
- Risk of Acute Complications With Rocuronium vs Cisatracurium in Patients With Chronic Kidney DiseaseRecruitingPhase 4The University of Texas Medical Branch, GalvestonNCT07203287Written as Neostigmine
- Pharmacological Reversal of Neuromuscular Blockade in Critically Ill PatientsRecruitingNot applicableSeoul National University HospitalNCT05993390Written as Neostigmine
- Antagonism of Neostigmine in Continuous Infusion of MivacuriumNot yet recruitingNot applicableBeijing Tongren HospitalNCT07524959Written as Neostigmine
- Neostigmine and Glycopyrrolate for the Treatment of Headache After Dural PunctureRecruitingPhase 2Mayo ClinicNCT05116930Written as Neostigmine
- Prophylactic Intravenous Injection of Neostigmine Plus Atropine Versus Ketorolac on Post-dural Puncture Headache in Patients Undergoing Infraumbilical SurgeriesNot yet recruitingPhase 1/2Assiut UniversityNCT06729047Written as Neostigmine
- Comparative Study Between Intrathecal Magnesium Sulfate, Neostigmine and Fentanyl As Adjuvant for Bubivacaine in Postoperative Analgesia in Lower Abdominal SurgeriesNot yet recruitingPhase 4Assiut UniversityNCT06685705Written as bupivacaine and Neostigmine
- Neostigmine Route for Acute Colonic Pseudo ObstructionRecruitingPhase 4University of Southern CaliforniaNCT04951726Written as Neostigmine
- The Effect of Neostigmine and Sugammadex on the Optic Nerve Sheath DiameterCompletedPhase 4Cukurova UniversityNCT07666984Written as Neostigmine + Atropine
- Neuromuscular Blockade Comparison for GI-2 Recovery After Bowel ResectionCompletedPhase 4University of California, IrvineNCT06112353Written as Neostigmine Injectable Solution
- Transdermal Administration of a Prokinetic Agent for Bowel Evacuation in Persons With SCICompletedEarly Phase 1James J. Peters Veterans Affairs Medical CenterNCT02370862Written as Neostigmine and Glycopyrrolate
- The Effects of Iontophoresed Vasoactive Drugs on Cutaneus Blood FlowTerminatedNot applicableUniversity Hospital, LinkoepingNCT04777383Written as Neostigmine
- MgSO4 as Adjuvants to Bupivacaine vs Neostigmine in TAP Block in Cesarean SectionCompletedPhase 2/3Assiut UniversityNCT06513013Written as Neostigmine
- Emergence AgitationActive, not recruitingNot applicableAin Shams UniversityNCT07253428Written as Neostigmine + Atropine
- The Impact of Sugammadex on Ileus After Abdominal Wall ReconstructionCompletedPhase 4Clayton PetroNCT05985343Written as Neostigmine / Glycopyrrolate
- Neostigmine/Glyco-pyrrolate 50 Mikrogram/kg or Sugammadex 2 mg/kg for Reversal of Neuromuscular Blockade in Elderly PatientsCompletedPhase 4Matias VestedNCT06228092Written as neostigmine/glycopyrrolate
- Use of Sugammadex for Reversal of Paralysis in MicrolaryngoscopyCompletedPhase 4West Virginia UniversityNCT03111121Written as neostigmine
- Using Diaphragm Ultrasonography, Sugammadex Recovers Diaphragmatic Function More Effectively Than Neostigmine.CompletedPhase 1Ain Shams UniversityNCT06982092Written as Neostigmine
- Study of Recovery of Strength After Surgery Comparing Two Different Medications for Reversal of Muscle RelaxantCompletedPhase 3Memorial Sloan Kettering Cancer CenterNCT03116997Written as Neostigmine+glycopyrrolate
- Ketamine Versus Neostigmine in Ultrasound-Guided Transversus Abdominis Plane Block in Caesarean SectionCompletedPhase 3Alexandria UniversityNCT06871033Written as TAP block with neostigmine
- Postoperative Urinary Retention in Patients After Noncardiac Surgery and Reversal of Neuromuscular BlockCompletedPhase 4The Cleveland ClinicNCT05545280Written as Neostigmine with glycopyrrolate
See all 82 studies that test Neostigmine →
Given in every arm · 6 — Neostigmine is usual care beside what is tested
- Ability to Maintain Saturation Levels Without Oxygen Supplementation as a Extubation Criteria Without TOF Monitoring EquipmentEnrolling by invitationNot applicableUniversity of SurabayaNCT06275542Written as Neostigmine
- The Impact of Intravenous Anaesthesia on Angiogenesis in Patients With Breast Cancer (TIVA/TCI-BC)CompletedPhase 2Iuliu Hatieganu University of Medicine and PharmacyNCT02839668Written as Neostigmine
- Intraoperative Lidocaine Infusion vs. Esmolol Infusion for Postoperative Analgesia in Laparoscopic CholecystectomyCompletedPhase 4B.P. Koirala Institute of Health SciencesNCT02327923Written as Neostigmine
- Effectiveness of Caudal Epidural Block on Intraoperative Blood Loss During Hypospadias RepairCompletedPhase 2/3Isfahan University of Medical SciencesNCT02752308Written as neostigmine and atropine
- Does Residual Muscular Weakness Lead to an Increase in Respiratory Complications in Bariatric Patients?CompletedNot applicableCoastal Anesthesiology ConsultantsNCT02037516Written as Neostigmine
- Impact of Anesthetic Choice (Sevoflurane Versus Desflurane) on Airway Reflex Recovery in the Context of Antagonized Neuromuscular BlockCompletedPhase 4University of California, San FranciscoNCT01199237Written as Neostigmine
As the comparator · 67 — what is tested is compared with Neostigmine
- Study on Neostigmine Acupoint Injection at Zusanli(ST36) for Treating Mechanical Ventilation-Associated Gastrointestinal DysfunctionNot yet recruitingNot applicableSoutheast University, ChinaNCT07692282Written as Neostigmine subcutaneous injection
- Impact of Sugammadex Versus Neostigmine on Early Postoperative Pulmonary FunctionRecruitingNot applicableShanghai Pulmonary Hospital, Shanghai, ChinaNCT07309393Written as Neostigmine
- Neuromuscular Blocking Agents on Gastrointestinal Function Following Colorectal SurgeryNot yet recruitingPhase 3Xijing HospitalNCT07271875Written as Neostigmine + Atropine
- The Clinical Effect of Sugammadex Sodium (Domestic) for Antagonizing Neuromuscular Blockade After Thoracic SurgeryRecruitingNot applicableThe Fourth Affiliated Hospital of Zhejiang University School of MedicineNCT06334562Written as Neostigmine
- Recovery Times of Half Dose Sugammadex and Neostigmine for Rocuronium-induced Neuromuscular BlockadeRecruitingPhase 1/2Universitas PadjadjaranNCT06794450Written as Neostigmine + Atropine
- Sugammadex on Laparoscopic Bariatric SurgeryNot yet recruitingNot applicableShanxi Bethune HospitalNCT06678451Written as Neostigmine
- Effects of Sugammadex and Conventional Reversal on Lung Function in Laparoscopic Abdominal SurgeryRecruitingNot applicableRhendra Hardy Mohamad ZainiNCT06210165Written as Neostigmine and atropine
- Sugammadex vs Neostigmine/Glycopyrrolate on Urinary Retention After Spine SurgeryCompletedPhase 4University of Missouri-ColumbiaNCT05887375Written as Neostigmine
- Sugammadex vs Neostigmine Reversal in Pediatric AppendectomyTerminatedPhase 4Emory UniversityNCT05256901Written as Neostigmine/Glycopyrrolate
- Sugammadex v.s. Neostigmine/GlycopyrrolateCompletedNot applicableNational Taiwan University HospitalNCT06398899Written as Group N: neostigmine/glycopyrrolate
- To Observe Haemodynamic Parameters Including, Heart Rate, Blood Pressure, Respiratory Rate , and Oxygen Saturation, With or Without Giving Reversal Agent on Extubation, in Patients Receiving Single Shot of Atracurium , and to Observe Post Operative Residual Paralysis and Airway Reflexes in PACU.CompletedPhase 1/2Ziauddin UniversityNCT07097441Written as neostigmine (reversal agent)
- Efficacy, Safety, and Pharmacokinetics of Sugammadex (MK-8616) for Reversal of Neuromuscular Blockade in Pediatric Participants Aged Birth to <2 Years (MK-8616-169)CompletedPhase 4Merck Sharp & Dohme LLCNCT03909165Written as Neostigmine + Glycopyrrolate
- Sugammadex Versus Neostigmine for Reversal of Neuromuscular Blockade at the End of Kidney Transplantation SurgeryCompletedPhase 4University of Colorado, DenverNCT03923556Written as Neostigmine
- Role of Curarization During Anesthesia for Laparoscopic HysterectomyCompletedPhase 2Campus Bio-Medico UniversityNCT03519633Written as Neostigmine
- Diaphragm Function After Reversal of Rocuronium-induced Neuromuscular Blockade With Sugammadex or Neostigmine in ChildrenCompletedNot applicableSeoul National University HospitalNCT05724550Written as Neostigmine
- Efficacy and Safety of Sugammadex in Thoracoscopy Thymectomy for Chinese Adults With Myasthenia GravisCompletedNot applicableBeijing Tongren HospitalNCT06436768Written as Neostigmine
- Impact of Sugammadex vs. Neostigmine Reversal on Post-Operative Recovery and ComplicationsCompletedPhase 4University Health Network, TorontoNCT03679611Written as Neostigmine
- Perioperative Respiratory Adverse events_sugammadexCompletedPhase 4Seoul National University HospitalNCT05354466Written as Neostigmine
- Sugammadex To IMprove Bowel FunctionCompletedPhase 4Oregon Health and Science UniversityNCT04546672Written as Neostigmine
- Low Dose of Sugammadex vs Neostigmine and Glycopyrrolate for the Reversal of RocuroniumCompletedPhase 4Ciusss de L'Est de l'Île de MontréalNCT05718934Written as Neostigmine and glycopyrrolate
Showing 20 of 67.
Codes
What other systems call Neostigmine · ClinicalTrials.gg INT007877
- MeSH (NLM) D009388NeostigmineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 3982TWQ96GNEOSTIGMINEConfirmed FDA, NLM, Wikidata
- RxNorm 7315Confirmed FDA, Wikidata
- Wikidata Q410546neostigmineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C75024NeostigmineOne source FDA
- DrugBank DB01400One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D009388 | Neostigmine | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 3982TWQ96G | NEOSTIGMINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 7315 | — | Confirmed FDA, Wikidata |
| Wikidata | Q410546 | neostigmine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C75024 | Neostigmine | One source FDA |
| DrugBank | DB01400 | — | One source Wikidata |
Also registered as neostigmine bromide (UNII 005SYP50G5 · RxNorm 82055) and neostigmine methylsulfate (UNII 98IMH7M386 · RxNorm 7316).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.