Hernia, Ventral clinical trials
The registry lists 230 studies for Hernia, Ventral across more than 10 countries. 45 are recruiting or about to start. 184 of them are mainly about Hernia, Ventral (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09. Counting its narrower condition Hernia, Umbilical too: 282 studies, 53 open.
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Status
Who runs them
The Cleveland Clinic (9) · Zealand University Hospital (8) · Bispebjerg Hospital (8) · The University of Texas Health Science Center, Houston (8) · Medtronic - MITG (7) · Assiut University (7) · University Hospital, Ghent (7) · C. R. Bard (4)
What is being tested here
Drugs under test in Hernia, Ventral studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Botulinum toxin type A | 2 | 0 | 3 |
| Acetaminophen | 1 | 0 | 1 |
| Ketorolac | 1 | 0 | 1 |
| Magnesium Sulfate | 1 | 0 | 1 |
| Tramadol | 1 | 0 | 1 |
| Gabapentin | 1 | 0 | 1 |
| Cyclobenzaprine | 1 | 0 | 1 |
| Bupivacaine | 0 | 1 | 5 |
| Liposomal Bupivacaine | 0 | 0 | 2 |
| Methocarbamol | 0 | 0 | 1 |
Drug classes tested here Local anesthetics 6
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026Compliance-Guided Abdominal Wall Closure Strategy in Large Ventral Hernia Repair · Swissmed Hospital
- Dec 2026GORE® ENFORM Biomaterial Product Study · W.L.Gore & Associates
- Dec 2026Opioid Education Ventral Hernia Repair · Tori Dotson
- Dec 2026Ventral Hernia Improvement of Treatment and Life · Line Marker
- Dec 2026ExtrAperitoneaL Plasty vs Intraperitoneal oNlay mEsh in Ventral Hernia Repair · University Hospital, Basel, Switzerland
- Jan 2027ORION Study: Mesh Position and Risk During Subsequent Minimally Invasive Abdominal Surgery · Istituto Auxologico Italiano
- Mar 2027Cryoneurolysis for Abdominal Wall Relaxation Prior to Ventral Hernia Repair · University of South Florida
- Mar 2027Ventral or Inguinal Hernia, Robotically Repaired With OviTex Mesh · Tela Bio Inc
- Apr 2027Targeted Prehabilitation With Physical Exercise and Inspiratory Muscle Training for Elderly Frail Patients Prior to Ventral Hernia Repair · Prisma Health-Upstate
- May 2027Comparative Evaluation of Preoperative Preparation Methods in Patients With Large Incisional Hernias · State Budget Public Health Institution Scientific Research Institute - Ochapovsky Regional Clinical Hospital
Who these studies take
Of the 26 Hernia, Ventral studies recruiting now, 19 (73%) set no upper age limit and 4 (15%) stop at 75 or younger. 1 (4%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 6 (23%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 23 (88%) | 23 (88%) |
| 30 | 25 (96%) | 25 (96%) |
| 40 | 25 (96%) | 25 (96%) |
| 50 | 25 (96%) | 25 (96%) |
| 65 | 24 (92%) | 24 (92%) |
| 75 | 23 (88%) | 23 (88%) |
| 85 | 20 (77%) | 20 (77%) |
Across all 230 studies, recruiting or not: 16% stop at 75 or younger and 7% at 65; 4% take children; 2% are for women only and 0% for men only; 15% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Hernia, Ventral studies take
Of 88 interventional studies with no phase under Hernia, Ventral, half reached primary completion within 37 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 37 mo19–56 · 88 studies | — | 33 mo19–48 · 75 studies |
| Observational | 39 mo7–72 · 20 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered5
- Robotic vs Open Retromuscular Abdominal Wall Hernia RepairNov 9, 2026NCT07925112
- Short Term Outcomes of for Primary Small Sized Midline Ventral HerniaNov 2, 2026NCT07908758
- Onlay vs. Sublay Mesh Hernioplasty for Primary Ventral HerniaOct 26, 2026NCT07896278
- Duramesh Versus Minimally Invasive IPOM for High-Risk Umbilical Hernia RepairsOct 19, 2026NCT07881354
- Cryoneurolysis for Abdominal Wall Relaxation Prior to Ventral Hernia RepairOct 15, 2026NCT07874724
Studies
Recruiting first, then most recently updated. Showing 50 of 230. Browse all 230 → or search them.
- Robotic vs Open Retromuscular Abdominal Wall Hernia RepairNot yet recruitingNCT07925112
- Duramesh Versus Minimally Invasive IPOM for High-Risk Umbilical Hernia RepairsRecruitingNCT07881354Not applicable1 country
- GORE® ENFORM Biomaterial Product StudyRecruitingNCT04718168Not applicable1 country
- Preoperative BOTOX® Injection for Large Ventral Hernia RepairRecruitingNCT07220382Phase 41 country
- The IMPACT Study: Personalized Physical Therapy for Better Recovery and a Stronger Core After Hernia SurgeryNot yet recruitingNCT07145099Not applicable1 country
- Cryoneurolysis for Abdominal Wall Relaxation Prior to Ventral Hernia RepairNot yet recruitingNCT07874724Not applicable1 country
- Standard Closure vs. Integrated Mesh-Fascial Closure (IMFC) for Incisional Hernia RepairRecruitingNCT07843225Not applicable1 country
- Epidural Analgesia Versus Opioid-sparing Analgesia for Open Ventral Hernia Repair With Transversus Abdominis ReleaseRecruitingNCT07840183Phase 41 country
- Compliance-Guided Abdominal Wall Closure Strategy in Large Ventral Hernia RepairRecruitingNCT07422441Not applicable1 country
- Image-Guided Herniorrhaphy StudyNot yet recruitingNCT07267494Not applicable1 country
- Study of AGN-151607-DP to Assess Adverse Events and Change in Disease Activity in Adult Participants Undergoing Open Abdominal Ventral Hernia RepairRecruitingNCT07226791Phase 21 country
- Robotic Single Port Ventral Hernia RepairRecruitingNCT07755657Not applicable1 country
- Risk Factors for Mesh Infection After Abdominal Wall ReconstructionRecruitingNCT077257181 country
- Hernia Sac Flap Coverage of Mesh in Bony-Edged Ventral Hernia RepairRecruitingNCT07720154Not applicable1 country
- Robotic Versus Open Ventral Hernia RepairRecruitingNCT05472987Not applicable1 country
- ExtrAperitoneaL Plasty vs Intraperitoneal oNlay mEsh in Ventral Hernia RepairRecruitingNCT06367309Not applicable1 country
- oPen Versus RobotIc retrOmuscular Repair in Medium to Large Ventral HerniasRecruitingNCT06364306Not applicable2 countries
- Recover@Home Postoperative Follow-up StudyNot yet recruitingNCT07714343Not applicable1 country
- Opioid Education Ventral Hernia RepairEnrolling by invitationNCT07639281Not applicable1 country
- Targeted Prehabilitation With Physical Exercise and Inspiratory Muscle Training for Elderly Frail Patients Prior to Ventral Hernia RepairEnrolling by invitationNCT06874413Not applicable1 country
- Ventral or Inguinal Hernia, Robotically Repaired With OviTex MeshRecruitingNCT04779918Not applicable1 country
- Prospective Study of Minimally Invasive (Laparoscopic and Robotic) Hernia Repair (Incisional and Primary, Midline and Lateral, Not Inguinal)RecruitingNCT075442381 country
- Comparative Evaluation of Preoperative Preparation Methods in Patients With Large Incisional HerniasRecruitingNCT07549113Not applicable1 country
- Ventral Hernias Following Cytoreductive Surgery : Incidence, Risk Factors and Surgical Management.RecruitingNCT074514831 country
- Preoptimisation in Ventral Hernia SurgeryRecruitingNCT07316426Not applicable1 country
- Emergency Hernia RepairNot yet recruitingNCT07314398
- Comparison of Two Plane Blocks Used in Open Ventral Hernia Repair OperationsNot yet recruitingNCT07163026Not applicable1 country
- A Prospective Study of Fortiva in Hernia RepairEnrolling by invitationNCT061019791 country
- Quadratus Lumborum Versus Placebo in Open Ventral Hernia RepairNot yet recruitingNCT06953635Not applicable1 country
- Ventral Hernia Improvement of Treatment and LifeEnrolling by invitationNCT068643771 country
- Abdominoplasty with Ventral Hernia Repair Versus Hernioplasty .Not yet recruitingNCT05792839Not applicable
- Anovo Surgical System in Ventral HerniaRecruitingNCT06457971Not applicable2 countries
- Sublay Versus Intraperitoneal Onlay Mesh Repair in Large Ventral HerniasNot yet recruitingNCT06643234Not applicable
- STRONG for Surgery & Strong for Life - Intensive Prehabilitation for Risk Reduction in Ventral Hernia RepairRecruitingNCT06611462Not applicable1 country
- Factors Influencing the Results of Treatment in Patients With Hernias of Various LocalizationsRecruitingNCT059202001 country
- Evaluation of Posterior Component Separation Technique in the Management of Complex Ventral Hernia.Not yet recruitingNCT06352489Not applicable
- Only Mesh Fixation With Glue of Ventral/Incisional Laparoscopic Hernia RepairNot yet recruitingNCT06183840Not applicable
- Minimally Invasive Techniques in Ventral HernioplastyNot yet recruitingNCT06255314Not applicable1 country
- Sutured vs Sutureless Mesh Fixation for Onlay Ventral Hernia RepairNot yet recruitingNCT06209450Not applicable
- Ventral Mesh Hernioplasty : Laparoscopic Versus Open SublayNot yet recruitingNCT06149858Not applicable
- Bariatric SUrgery With Mesh REpair of Ventral Hernia: a Randomized Controlled TrialRecruitingNCT05488288Phase 31 country
- Mass Closure vs Layer by Layer ClosureRecruitingNCT06016426Not applicable1 country
- Performance of Biologic Mesh Materials in Abdominal Wall ReconstructionRecruitingNCT02703662Phase 2/31 country
- Robotic Versus Hybrid Assisted Ventral Hernia RepairRecruitingNCT05233020Not applicable1 country
- Effect of Prehabilitation on Surgical Outcomes of Abdominally-based Plastic Surgery ProceduresRecruitingNCT04787874Not applicable1 country
- ORION Study: Mesh Position and Risk During Subsequent Minimally Invasive Abdominal SurgeryActive, not recruitingNCT073849621 country
- Assessment of GORE® SYNECOR Biomaterial in Focused Patient Populations and Long-Term ApplicationActive, not recruitingNCT050940894 countries
- Cytokine Response to Abdominal Wall ReconstructionCompletedNCT074225841 country
- Short Term Outcomes of for Primary Small Sized Midline Ventral HerniaCompletedNCT07908758Not applicable1 country
- Onlay vs. Sublay Mesh Hernioplasty for Primary Ventral HerniaCompletedNCT07896278Not applicable1 country