Drug
Nalmefene clinical trials
Also written Selincro.
- studies test it
- 35
- open now
- 2
- in phase 3
- 9
- first study started
- 2005
Keep track of what changes. Save the nalmefene studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Brand
Combined with it in one product
Studies by the year they started
35 studies that test it; most in 2015 (5)
| Year | Studies |
|---|---|
| 2005 | 2 |
| 2008 | 1 |
| 2009 | 3 |
| 2013 | 1 |
| 2014 | 2 |
| 2015 | 5 |
| 2016 | 4 |
| 2017 | 3 |
| 2018 | 2 |
| 2021 | 4 |
| 2022 | 2 |
| 2023 | 2 |
| 2024 | 2 |
| 2026 | 2 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 1
- Phase 1
- 13
- Phase 2
- 8
- Phase 3
- 9
- Phase 4
- 4
- No phase
- 2
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 20 · Other 15
H. Lundbeck A/S (6) · Opiant Pharmaceuticals Inc (3) · Otsuka Pharmaceutical Co., Ltd. (3) · Purdue Pharma LP (2) · Tharimmune Inc (2) · Somaxon Pharmaceuticals (2) · National Institute on Alcohol Abuse and Alcoholism (NIAAA) (1) · Knoa Pharma LLC (1)
Often tested with
Tested in the same studies.
Magnesium Chloride (1) · Dexmedetomidine (1) · Baclofen (1) · Low-Dose Naltrexone (1) · Naloxone (1)
Studies
Open first, then newest update. How each study uses nalmefene is read from its arms, and is right about nine times in ten.
Testing it · 35
- TH104 for the Treatment of Pruritus in Primary Biliary CholangitisNot yet recruitingPhase 2Tharimmune IncNCT06733519Written as Nalmefene
- NAlmefene Versus Placebo in Addition to Treatment As Usual on Craving in Behavioural AddictionsRecruitingPhase 3Nantes University HospitalNCT05540288Written as Nalmefene
- Title: Effect of Opioid Receptor Modulation on Alcohol Self-Administration and Neural Response to Alcohol Cues in Heavy Drinkers: Role of OPRM1 Gene VariationCompletedPhase 1National Institute on Alcohol Abuse and Alcoholism (NIAAA)NCT02639273Written as Nalmefene
- Reversal of Opioid-induced Respiratory Depression With Opioid AntagonistsTerminatedPhase 1Leiden University Medical CenterNCT05338632Written as Nalmefene HCl injection
- Pharmacokinetic (PK) Evaluation of Nalmefene FormulationsCompletedPhase 1Knoa Pharma LLCNCT07543276Written as Nalmefene + 0.94% MgCl2
- Effect of Nalmefene on the Quality of Resuscitation in Patients Under General AnesthesiaCompletedPhase 4RenJi HospitalNCT04713358Written as Nalmefene
- Pharmacodynamic Evaluation of Intranasal NalmefeneCompletedPhase 1Opiant Pharmaceuticals IncNCT04828005Written as Nalmefene hydrochloride
- Pharmacodynamic Evaluation of Intramuscular Nalmefene Autoinjector 1.5 mg Compared to Intranasal Narcan 4 mgCompletedPhase 1Purdue Pharma LPNCT06719986Written as Nalmefene HCl injection
- An Evaluation of The Absolute Bioavailability of TH104CompletedPhase 1Tharimmune IncNCT06198686Written as Nalmefene
- Nalmefene vs Naloxone for the Treatment of Recurrent Respiratory Depression After Opioid OverdoseWithdrawnPhase 3University of New MexicoNCT06408714Written as Nalmefene Injection
- Pharmacokinetic Evaluation of Intranasal NalmefeneCompletedPhase 1Opiant Pharmaceuticals IncNCT04759768Written as Nalmefene Hydrochloride
- Pharmacokinetic Evaluation of Intranasal Nalmefene Using Three Dosing RegimensCompletedPhase 1Opiant Pharmaceuticals IncNCT05219669Written as Nalmefene Hydrochloride
- Nalmefene in Patients With Alcoholic Compensated Cirrhosis for the Treatment of Alcohol Dependence.WithdrawnPhase 3Centre Hospitalier Universitaire, AmiensNCT02824354Written as Nalmefene (Selincro®) 18 mg tablet
- Clinical Outcomes From NalmefeneWithdrawnPhase 4Purdue Pharma LPNCT05808881Written as Nalmefene Hydrochloride Injection
- Effect of Dexmedetomidine Combined With Low-dose Nalmefene on Preventing Remifentanil-induced Postoperative HyperalgesiaCompletedNot applicableTianjin Medical University General HospitalNCT03096730Written as Nalmefene
- Patient Driven Recovery With Nalmefene and CoachingCompletedPhase 1Yale UniversityNCT03279562Written as Nalmefene
- Nalmefene, Baclofen and Impulsivity in Subjects With Alcohol Use Disorder and Healthy Control SubjectsCompletedPhase 2Prof. Daniele ZullinoNCT03034408Written as Nalmefene
- St. PETERsburg Pain and Alcohol Intervention With Naltrexone and NalmefeneCompletedPhase 1/2Boston Medical CenterNCT03278886Written as Nalmefene
- A Long-term Extension Study for the Phase 3 Study of Nalmefene (339-14-001) in Patients With Alcohol DependenceCompletedPhase 3Otsuka Pharmaceutical Co., Ltd.NCT02382276Written as Nalmefene hydrochloride
- A Multicenter, Randomized, Double-blind, Placebo-controlled, 3-parallel-group Comparison Trial to Investigate the Effect of Nalmefene on Alcohol Consumption Reduction in Patients With Alcohol Dependence (Phase 3 Trial)CompletedPhase 3Otsuka Pharmaceutical Co., Ltd.NCT02364947Written as Nalmefene hydrochloride
Codes
What other systems call nalmefene · ClinicalTrials.gg INT003113
- MeSH (NLM) C038981nalmefeneConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) TOV02TDP9INALMEFENEConfirmed FDA, NLM, Wikidata
- RxNorm 31479Confirmed FDA, Wikidata
- Wikidata Q4353252nalmefeneConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C61855NalmefeneOne source FDA
- DrugBank DB06230One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C038981 | nalmefene | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | TOV02TDP9I | NALMEFENE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 31479 | — | Confirmed FDA, Wikidata |
| Wikidata | Q4353252 | nalmefene | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C61855 | Nalmefene | One source FDA |
| DrugBank | DB06230 | — | One source Wikidata |
Also registered as nalmefene hydrochloride (UNII K7K69QC05X · RxNorm 236069) and nalmefene hydrochloride dihydrate (UNII 52Z0G7QVJX).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.