Gambling clinical trials

The registry lists 158 studies for Gambling across more than 10 countries. 42 are recruiting or about to start. 145 of them are mainly about Gambling (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06.

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Status

Completed: 82
Recruiting: 24
Status unknown: 23
Not yet recruiting: 18
Withdrawn: 5
Terminated: 4

Phase

Phase 2: 18
Phase 3: 8
Phase 1: 6
Phase 4: 4

Where

United States: 38
France: 28
Canada: 22
Sweden: 14
Spain: 6
Finland: 4

Who runs them

Nantes University Hospital (16) · Centre for Addiction and Mental Health (12) · Karolinska Institutet (7) · UConn Health (6) · Region Skane (5) · University of Chicago (5) · Shanghai Mental Health Center (4) · University of Sao Paulo (3)

What is being tested here

Drugs under test in Gambling studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

Drug	Open	Phase 3	All
Nalmefene	1	2	2
Naltrexone	0	0	5
Acetylcysteine	0	0	2
Tolcapone	0	0	2
Naloxone	0	0	2
Topiramate	0	1	2
Milk-thistle extract	0	0	1
Ecopipam	0	0	1
Acamprosate	0	0	1
Bupropion	0	0	1

Drug classes tested here Opioid antagonists 1 open · Antipsychotics 3

Coming up

2phase 3 studies under way

14studies finish main data collection within a year1 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Jul 2027NAlmefene Versus Placebo in Addition to Treatment As Usual on Craving in Behavioural Addictions · Phase 3 · Nantes University Hospital
Nov 2026Efficacy and Safety of Combo-stim Deep Brain Stimulation for Treatment-refractory Mental Disorders · Shanghai Mental Health Center
Nov 2026Effect of High-Intensity Transcranial Alternating Current Stimulation on Gambling Disorder: A Randomized Controlled Trial · Shanghai Mental Health Center
Dec 2026ACT-Based Intervention for Problem Gambling · Universidad Europea de Madrid
Dec 2026Contingency Management to Reinforce Attendance to Cognitive Behavioral Treatment for Gambling Disorder · East Tennessee State University
Dec 2026Contingency Management as an Adjunct Treatment for Rural and Remote Disordered Gamblers · University of Lethbridge
Dec 2026Effects of Proactive Call to Customers of Norsk Rikstoto (Horse Gambling Operator in Norway): A Randomized Controlled Study · University of Bergen
Jan 2027Digital Cognitive Behavioral Therapy for Gambling Disorder · Universitas Indonesia
Jan 2027Internet-based Versus Synchronous Cognitive Behavioural Therapy for Patients With Gambling Disorder · Aarhus University Hospital
Feb 2027Interaction Between Atypical Work Schedules and/or Idel Time at Work on At-risk Gambling Practices · Centre Hospitalier Universitaire de Nīmes

Who these studies take

Of the 24 Gambling studies recruiting now, 14 (58%) set no upper age limit and 10 (42%) stop at 75 or younger. 1 (4%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 5 (21%) take healthy volunteers.

Recruiting studies that take each age, of 24
Age	Women	Men
10	0 (0%)	0 (0%)
18	22 (92%)	22 (92%)
30	24 (100%)	24 (100%)
40	24 (100%)	24 (100%)
50	24 (100%)	24 (100%)
65	21 (88%)	21 (88%)
75	14 (58%)	14 (58%)
85	14 (58%)	14 (58%)

Across all 158 studies, recruiting or not: 47% stop at 75 or younger and 33% at 65; 8% take children; 1% are for women only and 3% for men only; 26% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Gambling studies take

Of 47 interventional studies with no phase under Gambling, half reached primary completion within 16 months of starting, counting those still running.

Start to primary completion	Every sponsor	Industry	Non-industry
Interventional, no phase	16 mo10–51 · 47 studies	—	16 mo10–51 · 47 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 11, 2026.

Started recruiting1

Psilocybin AsSisted pSychotherapy for the treatmENt of Gambling disordER : a Pilot StudyOct 16, 2026NCT07391332

Newly registered1

Low-Intensity Focused Ultrasound for Gambling DisorderNov 6, 2026NCT07923032

Studies

Recruiting first, then most recently updated. Showing 50 of 158. Browse all 158 → or search them.