Drug
Misoprostol clinical trials
Also written Cytotec.
- studies test it
- 309
- open now
- 16
- in phase 3
- 72
- first study started
- 1999
Keep track of what changes. Save the Misoprostol studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Brand
- Cytotec
- 88
Studies by the year they started
305 studies that test it; most in 2016 (24); 1 more planned to start later
| Year | Studies |
|---|---|
| 1999 | 3 |
| 2000 | 2 |
| 2001 | 1 |
| 2002 | 1 |
| 2003 | 2 |
| 2004 | 6 |
| 2005 | 11 |
| 2006 | 7 |
| 2007 | 11 |
| 2008 | 12 |
| 2009 | 13 |
| 2010 | 7 |
| 2011 | 12 |
| 2012 | 19 |
| 2013 | 15 |
| 2014 | 21 |
| 2015 | 17 |
| 2016 | 24 |
| 2017 | 15 |
| 2018 | 22 |
| 2019 | 16 |
| 2020 | 14 |
| 2021 | 13 |
| 2022 | 10 |
| 2023 | 10 |
| 2024 | 9 |
| 2025 | 9 |
| 2026 | 3 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 10
- Phase 1
- 12
- Phase 2
- 52
- Phase 3
- 72
- Phase 4
- 75
- No phase
- 108
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 2 · Other 307
Gynuity Health Projects (43) · Cairo University (19) · Ain Shams University (18) · Assiut University (12) · Aswan University Hospital (9) · Montefiore Medical Center (4) · Ain Shams Maternity Hospital (4) · Hawler Medical University (4)
Often tested with
Tested in the same studies.
Mifepristone (32) · Oxytocin (22) · Carbetocin (10) · Dinoprostone (9) · Tranexamic Acid (7) · Isosorbide mononitrate (3) · Letrozole (3) · Arginine Vasopressin (3)
Studies
Open first, then newest update. How each study uses Misoprostol is read from its arms, and is right about nine times in ten.
Testing it · 309
- Office Hysteroscopy in Postmenopausal Women: A Randomized Trial of Cervical Preparation StrategiesRecruitingNot applicableFaculty of Medicine of TunisNCT07697781Written as Misoprostol ( Cytotec) 200 microgram a tablet
- Optimal Time Interval Between Mifepristone and Misoprostol Administration for Early Pregnancy LossNot yet recruitingPhase 3University of PennsylvaniaNCT07506512Written as 200mg mifepristone and 800mg misoprostol
- Period Pills for Menstrual Regulation: A New Reproductive Health OptionRecruitingPhase 4University of California, San FranciscoNCT07671989Written as Mifepristone + Misoprostol
- Use Misoprostol to Optimize Prevention of Cervical CancerRecruitingNot applicableUniversity of Alabama at BirminghamNCT06669533Written as Misoprostol
- Induction of Labor in Morbidly Obese PatientsRecruitingEarly Phase 1University of Maryland, BaltimoreNCT06199154Written as Misoprostol
- Mifepristone vs MisoprostolRecruitingPhase 1Montefiore Medical CenterNCT06502158Written as Misoprostol
- Foley Balloon for Cervical Preparation Before Dilation and EvacuationRecruitingNot applicableStony Brook UniversityNCT06850974Written as Misoprostol
- Comparison of Efficacy and Safety of Oral Versus Vaginal Misoprostol in Missed Abortion in First Trimester of PregnancyNot yet recruitingPhase 1Hamna KhaliqNCT07526064Written as Oral misoprostol
- Misoprostol Before Caesarean SectionRecruitingPhase 4Kafrelsheikh UniversityNCT06946914Written as Misoprostol
- Comparison Between Preoperative Vaginal and Postoperative Sublingual Misoprostol for Prevention of Postpartum Hemorrhage During Cesarean SectionNot yet recruitingPhase 3Assiut UniversityNCT06765473Written as Misoprostol
- Misoprostol Versus Oxytocin Infusion On Reducing Blood Loss During Abdominal MyomectomyRecruitingPhase 3Cairo UniversityNCT06325501Written as Misoprostol 200mcg Tab
- Prevention of Recurrent Ulcer Bleeding in Patients With Idiopathic Gastroduodenal UlcerRecruitingPhase 4Chinese University of Hong KongNCT03675672Written as Misoprostol Oral Tablet
- Misoprostol for Induction of Labor in Obese Women: Comparison Between 25 and 50 mcg Oral AdministrationRecruitingNot applicableCentro Hospitalar e Universitário de Coimbra, E.P.E.NCT05857059Written as Misoprostol 25 mcg
- MISOPROSTOL FOR THE TREATMENT OF SUSPECTED POSTPARTUM RETAINED PRODUCTS OF CONCEPTIONRecruitingNot applicableAssuta Ashdod HospitalNCT06009679Written as Misoprostol 200mcg Tab
- Pre Versus Post-operative Misoprostol in Reducing Blood Loss After Cesarean SectionRecruitingPhase 4Cairo UniversityNCT05928871Written as Misoprostol 200mcg Tab
- Comparison of Oral Versus Vaginal Misoprostol for Labour Induction at TermRecruitingPhase 2/3Services Institute of Medical Sciences, PakistanNCT05957666Written as Misoprostol Oral Tablet
- Different Medications to Induce LaborCompletedPhase 3Icahn School of Medicine at Mount SinaiNCT06259097Written as Misoprostol
- Letrozole and Misoprostol for Early Pregnancy Loss ManagementCompletedPhase 2University of PennsylvaniaNCT06452719Written as Misoprostol
- Comparison of the Efficacy of Misoprostol and Tranexamic Acid for Postpartum Hemorrhage Prophylaxis in Cesarean DeliveryCompletedPhase 4Ankara Etlik City HospitalNCT06970483Written as Misoprostol 200mcg Tab
- Surgical vs. Medical Abortion on Sexual Function After Early Pregnancy LossCompletedNot applicableHarran UniversityNCT07646275Written as mifepristone and misoprostol
See all 309 studies that test Misoprostol →
Given in every arm · 40 — Misoprostol is usual care beside what is tested
- Letrozole Plus Misoprostol Versus Misoprostol Alone for Treating Women With Missed MiscarriageRecruitingPhase 4Nishtar Medical UniversityNCT07160855Written as Misoprostol (given vaginally)
- Double Simultaneous Uterotonic Agents Versus Single Agent Regimen to Prevent Early Postpartum HemorrhageRecruitingPhase 3Stony Brook UniversityNCT05245227Written as Sublingual Misoprostol
- Simultaneous Mifepristone and Misoprostol Versus Misoprostol Alone for Induction of Labor of Nonviable Second Trimester Pregnancy: a Pilot Randomized Controlled TrialCompletedPhase 4Washington University School of MedicineNCT05322252Written as Misoprostol
- Laminaria Japonicum Followed by Misoprostol Versus Misoprostol Alone for Mid-Trimester Abortion Induction in Scarred UterusCompletedPhase 4Pavly Maged Jimmy FouadNCT07465016Written as Misoprostol ( Cytotec) 200 microgram a tablet
- Termination Of Anembryonic PregnancyWithdrawnPhase 2Assiut UniversityNCT02573051Written as Misoprostol
- Pre-Operative Effects of Mifepristone on Dilation and Evacuation ServicesCompletedNot applicableStanford UniversityNCT01862991Written as Misoprostol
- Value of Mifepristone in Cervical Preparation Prior to Dilation and Evacuation 19-24 WeeksCompletedNot applicableStanford UniversityNCT01615731Written as Misoprostol
- Ulipristal Acetate for Use in Early Pregnancy LossCompletedPhase 2University of North Carolina, Chapel HillNCT05216952Written as Misoprostol Pill
- Propranolol and Misoprostol Versus Misoprostol Alone for Induction of Labor in PrimigravidasCompletedPhase 2Ahmed mohamed fathy ismailNCT04533841Written as Misoprostol
- Same-Day Mifepristone-Misoprostol Compared to Misoprostol Only for Surgical Abortion Cervical PreparationCompletedPhase 4Medstar Health Research InstituteNCT02412618Written as Misoprostol
- Use of Ulipristal Acetate in Induction of Second Trimester Missed AbortionCompletedPhase 4Ain Shams UniversityNCT04989400Written as Misoprostol
- Non-surgical Alternatives to Treatment of Failed Medical AbortionTerminatedPhase 4Gynuity Health ProjectsNCT02704481Written as Misoprostol
- Evening Primrose Oil to Misoprostol During Induction of Second-trimester Missed MiscarriageCompletedPhase 4Assiut UniversityNCT03584698Written as Misoprostol 100Mcg Tab
- Vaginal Misoprostol With Intracervical Foley Catheter in Induction of LaborCompletedPhase 4Ain Shams UniversityNCT03682718Written as Misoprostol
- Isonicotinic Acid Hydrazide Pretreatment With Misoprostol Induction of Abortion in First-trimester Missed MiscarriageStatus unknownPhase 4Aswan University HospitalNCT04499976Written as Misoprostol
- Isonicotinic Acid Hydrazide (INH) Pretreatment With Misoprostol Versus Misoprostol Alone in Missed AbortionStatus unknownNot applicableAswan University HospitalNCT04500002Written as Misoprostol
- Comparing Two Medical Treatments for Early Pregnancy Failure.TerminatedPhase 4Radboud University Medical CenterNCT03212352Written as Misoprostol
- Comparative Effectiveness of Pregnancy Failure Management RegimensCompletedPhase 3University of PennsylvaniaNCT02012491Written as Misoprostol
- Using Isosorbide Mononitrate in Reducing Time in Induction of Labor in Post Date WomenStatus unknownPhase 2Abdelrahman Ali Fadel Youssef MohamedNCT03854383Written as Misoprostol
- Sublingual Misoprostol With or Without Intravenous Tranexamic Acid During Hemorrhagic Cesarean SectionStatus unknownNot applicableAswan University HospitalNCT03774706Written as Misoprostol
Showing 20 of 40.
As the comparator · 30 — what is tested is compared with Misoprostol
- Combined Misoprostol and Cervical Balloon vs Misoprostol Alone for Induction on the First Day in PrimiparasNot yet recruitingPhase 4Peking University First HospitalNCT07690007Written as Misoprostol
- Carbetocin vs Misoprostol for Postpartum Hemorrhage PreventionNot yet recruitingNot applicableWestern Galilee Hospital-NahariyaNCT07353281Written as Misoprostol
- Effect of Dexamethasone on Labour Induction in Term PregnanciesRecruitingEarly Phase 1Cairo UniversityNCT07109258Written as Misoprostol 25 mcg
- Prostaglandins Versus Trans-cervical Balloon for Induction of Labor in Fetal Growth Restriction (PROBIN)RecruitingNot applicableUniversity Hospital, BordeauxNCT05674487Written as Misoprostol
- Balloon + Oxytocin Versus Oral Misoprostol to Induce Labor in Case of PROM (RUBAPRO2)TerminatedPhase 4University Hospital, Clermont-FerrandNCT05568745Written as Misoprostol Oral Tablet
- Tranexamic Acid Versus Misoprostol to Reduce Blood Loss During and After Cesarean SectionCompletedPhase 4Medicare Hospital (Pvt) LimitedNCT07712510Written as rectal misoprostol
- Cervical Ripening Balloon Compared With Vaginal Misoprostol for Cervical Ripening in Obese Woman at TermActive, not recruitingNot applicableHUDDA AhmadNCT07685756Written as Misoprostol
- The HYsteroscopic Miscarriage MaNagement Trial: A Pilot RCT Investigating a Novel Management Pathway for RPOCCompletedNot applicableBirmingham Women's and Children's NHS Foundation TrustNCT04751500Written as Medical management
- Efficacy of Carbetocin Versus Oxytocin Plus Misoprostol in Decreasing Blood Loss During Cesarean SectionCompletedPhase 4Ain Shams Maternity HospitalNCT05664659Written as Oxytocin + misoprostol
- Misoprostol With Mechanical Dilation Versus Oxytocin With Mechanical Dilation for High-risk Pregnancy InductionsCompletedNot applicableThomas Jefferson UniversityNCT04492072Written as Misoprostol
- Comparative Efficacy of Lidocaine Spray Versus Vaginal Misoprostol in IUD InsertionCompletedPhase 3Cairo UniversityNCT04339049Written as vaginal misoprostol
- Uterotonics for Severe PreeclampsiaCompletedNot applicableAssiut UniversityNCT04756661Written as Misoprostol
- Methods to Reduce Blood Loss in Abdominal MyomectomyStatus unknownPhase 4Cairo UniversityNCT04595812Written as Misoprostol 200mcg Tab vaginal
- Vaginal Dinoprostone Versus Vaginal Misoprostol Prior to Diagnostic Office Hysteroscopy in Postmenopausal PatientsCompletedPhase 4Cairo UniversityNCT04044079Written as Misoprostol
- Vaginal Misoprostol and Dinoprostone and Isonicotinic Acid Hydrazide Prior to Copper Intrauterine Device InsertionStatus unknownNot applicableAswan University HospitalNCT04505943Written as misoprostol
- Vaginal Misoprostol and Dinoprostone Prior to Copper Intrauterine Device Insertion in WomenStatus unknownNot applicableAswan University HospitalNCT04505917Written as misoprostol
- Comparison of Vaginal Misoprostol and Dinoprostone Prior to Copper Intrauterine Device Insertion in Nulliparous WomenCompletedPhase 4Cairo UniversityNCT04080336Written as Misoprostol
- Tranexamic Acid Versus Vaginal Misoprostol in Abdominal MyomectomyStatus unknownPhase 4Cairo UniversityNCT04358965Written as vaginal misoprostol
- Dinoprostone vs Misoprostol Before LNG-IUD InsertionStatus unknownPhase 3Cairo UniversityNCT04301349Written as vaginal misoprostol
- Comparison of Vaginal Misoprostol and Dinoprostone Prior to Copper Intrauterine Device Insertion in Women Delivered Only by Cesarean DeliveryStatus unknownPhase 4Cairo UniversityNCT04080349Written as Misoprostol 200Mcg Tab
Showing 20 of 30.
Codes
What other systems call Misoprostol · ClinicalTrials.gg INT008535
- MeSH (NLM) D016595MisoprostolConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 0E43V0BB57MISOPROSTOLConfirmed FDA, NLM, Wikidata
- RxNorm 42331Confirmed FDA, Wikidata
- Wikidata Q416025misoprostolConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C1313MisoprostolOne source FDA
- DrugBank DB00929One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D016595 | Misoprostol | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 0E43V0BB57 | MISOPROSTOL | Confirmed FDA, NLM, Wikidata |
| RxNorm | 42331 | — | Confirmed FDA, Wikidata |
| Wikidata | Q416025 | misoprostol | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C1313 | Misoprostol | One source FDA |
| DrugBank | DB00929 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.