A Phase 4 interventional study of Isonicotinic Acid and Placebo in Abortion, Missed, sponsored by Aswan University Hospital. Status unknown at 1 site in Egypt. Open to female participants aged 18 Years to 45 Years. Per ClinicalTrials.gov, last updated 2020-08-05.
Sponsored by Aswan University Hospital · Phase 4, Interventional, and Treatment
Among 12 studies in Abortion, Missed with a site in Egypt — none open to participants now, none under way, none of them phase 3. Abortion, Missed · Egypt.
Among the 12 studies in Abortion, Missed with a site in Egypt, this one is the 3rd largest by planned enrollment of the 11 interventional ones, is the only one that started in 2020, is one of 2 in phase 4, and was the 8th registered.
48 studies on the registry are indexed under Abortion, Missed; 10 are open to participants now.
This study's planned enrollment of 240 is above the median of 110 across 41 interventional studies indexed under Abortion, Missed.
Browse Abortion, Missed studies →None of the 12 studies in Abortion, Missed with a site in Egypt is open now.
Of the 5 Abortion, Missed studies recruiting now, 0 (0%) set no upper age limit and 5 (100%) stop at 75 or younger; 0 take children under 18; 1 take healthy volunteers.
This study: 18 Years to 45 Years · female · no healthy volunteers.
The full table on the hub →12 studies; the count open now beside each. This study's row is marked.
First in 2015; this study’s year is marked. 1 started in 2020.
Median enrollment 140 across the 11 interventional studies, 320 across the 1 observational. Of the 5 that completed or were terminated, 0 (0%) have results posted.
None of the 12 has an industry lead sponsor. The 7 most frequent:
Aswan University Hospital is the lead sponsor of 97 studies on the registry; 3 are open to participants now.
Aswan University Hospital has 1 study filed under Abortion, Missed — fewer than ten, so there is no comparison to draw.
None of the studies under way reaches primary completion within a year.
Among the 12 studies in Abortion, Missed with a site in Egypt, from their registry updates:
Nothing recorded among them since 2026-09-25.
This study compares the success rate of Adjuvant isonicotinic acid hydrazide and misoprostol versus misoprostol alone for medical termination of first-trimester pregnancy among women with one or more previous cesarean deliveries.
In the past, the role of laminaria and prostaglandins in cervical dilatation and reducing intraoperative complications of cervical dilatation have been proven . Misoprostol is a synthetic analogue of prostaglandin E1 used to treat and prevent gastric ulcers, which is now widely used in obstetrics and gynecology. Its applications in obstetrics and gynecology include medical abortion in the first and second trimesters of pregnancy.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The protein in red blood cells that carries oxygen. A low level is anaemia, which can cause tiredness and breathlessness. Measured in g/dL or g/L (9 g/dL is 90 g/L).
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Hemoglobin (Hb)
The protein in red blood cells that carries oxygen. A low level is anaemia, which can cause tiredness and breathlessness. Measured in g/dL or g/L (9 g/dL is 90 g/L).
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
BMI (body mass index)
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
3 tablets of isonicotinic acid hydrazide 300 mg will be given as single daily dose, 900 mg per day for two days at home and the third dose will be given on admission to hospital on day 3 and will be followed by vaginal misoprostol 800 mcg every three hours up to maximum two doses.
Drug: Isonicotinic Acid · Drug: Misoprostol
three tablets of placebo will be given as a single daily dose, for two days at home and will be admitted on day 3 and continue treatment with misoprostol 800 mcg every three hours up to maximum two doses
Drug: Placebo · Drug: Misoprostol
Drug: Isonicotinic Acid then misoprostol Drug: Isonicotinic Acid 300mg total dose 900 mg per day for 3 days
Drug: placebo then misoprostol Drug: Placebo placebo for 3 days
Drug: Misoprostol Misoprosrol 800mcg will be given to all patients for induction of abortion
induction to abortion time
induction to abortion time
Time frame: 9 hours
number of patient with complete abortion
number of patient with complete abortion
Time frame: 9 hours
number of patient need for surgical evacuation of the products of conception
number of patient need for surgical evacuation of the products of conception
Time frame: 12 hours
Plan to share: No
No publications or documents are linked to this record.
Start is estimated for Sep 2020; primary completion for Apr 2021, 7 months later.
How these figures are worked out, and which studies are left out of them.
This study is status unknown, as verified in Aug 2020. You cannot join it, but the record below documents what was studied.
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Aswan University Hospital