Leiomyoma clinical trials
The registry lists 438 studies for Leiomyoma across more than 10 countries. 74 are recruiting or about to start. 354 of them are mainly about Leiomyoma (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Status
Who runs them
Repros Therapeutics Inc. (18) · Bayer (12) · InSightec (10) · Abbott (9) · AbbVie (8) · Gynesonics (7) · University Magna Graecia (7) · Philips Healthcare (6)
What is being tested here
Drugs under test in Leiomyoma studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Drug classes tested here Local anesthetics 1 open · Hormonal contraceptives 21 · NSAIDs 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Nov 2026Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids · Phase 3 · Qilu Pharmaceutical Co., Ltd.
- Dec 2026Terlipressin vs Placebo to Reduce Bleeding in Fibroid Surgery · Sevil Cankaya
- Dec 2026Stellate Ganglion Block and Dexmedetomidine for Postoperative Sleep in Women Undergoing Laparoscopic Gynecologic Surgery · Catherin Zhang
- Dec 2026Effect of Misoprostol on Fluid Deficit Volume in Hysteroscopic Myomectomy · Northwestern University
- Dec 2026The Effects of One-time Intraoperative Methadone During Laparoscopic Hysterectomy in Reducing Opioid Prescription. · Johns Hopkins University
- Dec 2026Evaluation of Salivary RNA in Subjects Scheduled for Surgery for a Gynecologic Pathology · ZIWIG
- Dec 2026Artificial Intelligence for the Intra-procedural Assessment of Uterine Artery Embolization · Emanuele Barabino
- Dec 2026The Impact of a Novel GnRH Antagonist With Add-back Therapy for Treatment of Uterine Fibroids and Endometriosis on Hemostasis Parameters · University Hospital, Geneva
- Dec 2026Prospective Study of TVRFA Treatment for FIGO Type 3-5 Uterine Fibroids · University of Novi Sad
- Dec 2026A Clinical Study on the Feasibility and Safety of Abdominal Endoscopic Single-port Surgery System to Assist Gynecological Day Surgery · Second Affiliated Hospital of Wenzhou Medical University
Who these studies take
Of the 43 Leiomyoma studies recruiting now, 21 (49%) set no upper age limit and 21 (49%) stop at 75 or younger. 3 (7%) take children under 18. 40 (93%) are for women only and 0 (0%) for men only; 9 (21%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (7%) | 1 (2%) |
| 18 | 38 (88%) | 3 (7%) |
| 30 | 43 (100%) | 3 (7%) |
| 40 | 43 (100%) | 3 (7%) |
| 50 | 36 (84%) | 3 (7%) |
| 65 | 24 (56%) | 3 (7%) |
| 75 | 23 (53%) | 3 (7%) |
| 85 | 22 (51%) | 3 (7%) |
Across all 438 studies, recruiting or not: 58% stop at 75 or younger and 56% at 65; 8% take children; 95% are for women only and <1% for men only; 25% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Leiomyoma studies take
Of 25 phase 3 interventional studies under Leiomyoma, half reached primary completion within 27 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 14 mo3–41 · 13 studies | — | — |
| Phase 3 | 27 mo23–41 · 25 studies | — | — |
| Interventional, no phase | 31 mo15–43 · 57 studies | — | 32 mo14–43 · 52 studies |
| Observational | 29 mo16–99 · 45 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting1
- Epidemiology and Risk Factors of Uterine Fibroids in ChinaOct 13, 2026NCT05840042
Newly registered3
- Prospective Study of TVRFA Treatment for FIGO Type 3-5 Uterine FibroidsNov 6, 2026NCT07923253
- Office Hysteroscopy Versus Operating-room Hysteroscopy for Uterine LesionsNov 2, 2026NCT07908615
- Predictors of Success and Failure of v-NOTES Hysterectomy for Large and Very Large UteriOct 26, 2026NCT07895953
Studies
Recruiting first, then most recently updated. Showing 50 of 438. Browse all 438 → or search them.
- Hereditary Leiomyomatosis Renal Cell Cancer - Study of the Genetic Cause and the Predisposition to Renal CancerRecruitingNCT000507521 country
- Office Hysteroscopy Versus Operating-room Hysteroscopy for Uterine LesionsNot yet recruitingNCT07908615Not applicable1 country
- Predictors of Success and Failure of v-NOTES Hysterectomy for Large and Very Large UteriRecruitingNCT078959531 country
- Epidemiology and Risk Factors of Uterine Fibroids in ChinaRecruitingNCT058400421 country
- The Effects of Uterine Fibroids on Pregnancy in WomenRecruitingNCT060209241 country
- A Prospective Validation Study of Radiomics in the Differential Diagnosis of Uterine Leiomyoma and Uterine SarcomaNot yet recruitingNCT07269535
- Radiomics-Based Non-Invasive MRI Differentiation of Uterine Sarcomas and FibroidsEnrolling by invitationNCT071290051 country
- Bearing nsPVA Embolization for Uterine Artery Embolization (BETTER-UAE)RecruitingNCT061536673 countries
- Stellate Ganglion Block and Dexmedetomidine for Postoperative Sleep in Women Undergoing Laparoscopic Gynecologic SurgeryRecruitingNCT07860203Not applicable1 country
- Prescription of Letrozole for Uterine MyomaRecruitingNCT06143631Phase 41 country
- LapBox® Manual Containment SystemNot yet recruitingNCT07767968Not applicable1 country
- Vaginal Sildenafil for Primary DysmenorrheaNot yet recruitingNCT07508358Phase 11 country
- Artificial Intelligence Into Ultrasound Diagnostics in Reproductive MedicineRecruitingNCT078109201 country
- QL Block in Laparoscopic MyomectomyRecruitingNCT05979493Phase 41 country
- Prospective Perioperative Clinical Registry for Women Undergoing Benign Gynecological SurgeryNot yet recruitingNCT077720761 country
- Safety and Efficacy of Microwave Ablation Alone Versus Microwave Ablation Combined With Chemical Ablation in the Treatment of Uterine Fibroids: A Prospective, Multicenter StudyNot yet recruitingNCT07754877Not applicable1 country
- Terlipressin vs Placebo to Reduce Bleeding in Fibroid SurgeryNot yet recruitingNCT07746349Not applicable
- Impact of Educational Videos on Pre-operative AnxietyEnrolling by invitationNCT07740759Not applicable1 country
- Deep Neuromuscular Blockade and a Low-Residue Diet for the Surgical Field in vNOTES HysterectomyRecruitingNCT07730970Not applicable1 country
- Cyclobenzaprine for Postoperative Pain in Minimally Invasive HysterectomyNot yet recruitingNCT07664956Phase 41 country
- FATIMA Trial: EGCG and Vitamin D3 for Prevention of Fibroid RecurrenceRecruitingNCT07647198Phase 21 country
- Effect of Misoprostol on Fluid Deficit Volume in Hysteroscopic MyomectomyRecruitingNCT07286188Phase 41 country
- The Impact of Myomectomy on IVF Outcomes: A Multicenter Randomized Controlled TrialNot yet recruitingNCT07578623Not applicable
- to Evaluate the Efficacy and Safety of KLH-2109 in Patients With Uterine Fibroids and MenorrhagiaRecruitingNCT07378098Phase 31 country
- The Impact of a Novel GnRH Antagonist With Add-back Therapy for Treatment of Uterine Fibroids and Endometriosis on Hemostasis ParametersRecruitingNCT07173127Not applicable1 country
- Single-channel Fibroid Morcellation System Used in Clinical Research on Laparoscopic MyomectomyNot yet recruitingNCT07512973Not applicable
- Transmucosal Uterosacral Electrical Stimulation for Pelvic Pain ReliefNot yet recruitingNCT07501676Not applicable1 country
- HIFU Versus Myomectomy for the Treatment of Symptomatic Uterine FibroidsRecruitingNCT06692335Not applicable1 country
- TEAS Combined With Triple Antiemetic Drugs to Prevent PONV in High-Risk PatientsRecruitingNCT07480785Not applicable1 country
- Phase II Study of CMS-D002 Capsule for Uterine Fibroids With MenorrhagiaRecruitingNCT07402369Phase 21 country
- The Effect of Uterine Manipulator Use During Abdominal Hysterectomy on Postoperative Sexual FunctionRecruitingNCT07431788Not applicable1 country
- Vitamin D, Epigallocatechin Gallate, D-chiro-inositol and Vitamin B6 in Uterine FibroidRecruitingNCT05448365Not applicable1 country
- Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine FibroidsRecruitingNCT06671548Phase 31 country
- The Effects of One-time Intraoperative Methadone During Laparoscopic Hysterectomy in Reducing Opioid Prescription.RecruitingNCT06536517Phase 21 country
- Role of Senescent Cells in Uterine Fibroid Pathogenesis (SOUL Study)RecruitingNCT061358701 country
- Efficacy of Ultrasound Guided Microwave Ablation in the Treatment of Uterine Fibroids.Not yet recruitingNCT07235787Not applicable1 country
- Artificial Intelligence for the Intra-procedural Assessment of Uterine Artery EmbolizationNot yet recruitingNCT072304441 country
- Comparing the Efficacy of TU-LESS and vNOTES for Hysterectomy of Enlarged UterusNot yet recruitingNCT06663553Not applicable1 country
- Prospective Validation Study of a Uterine Fibroid-Related Infertility Prediction ModelNot yet recruitingNCT07177534
- An Open-Label Study to Evaluate the Effect of Elix Cycle Balance & Elix Daily Harmony on Fibroid-related SymptomsRecruitingNCT07078682Not applicable1 country
- A Randomized Study Comparing Subtotal vs Total Hysterectomy Long Term OutcomesNot yet recruitingNCT06802198Not applicable1 country
- Comparison of Operative Hysteroscopy Performed in the Operating Room Versus Outpatient SettingsRecruitingNCT071466591 country
- POPQ Associated With Total Laparoscopic HysterectomyNot yet recruitingNCT071372991 country
- Relugolix Pregnancy Registry: An Observational Study of the Safety of Relugolix-Containing Therapy Exposure in Pregnant Women and Their OffspringRecruitingNCT057391231 country
- Ultrasound Transformation of Myomas During Relugolix-Estradiol-Norethisterone Treatment: The MySaturn StudyRecruitingNCT069530761 country
- A Phase 3B Study to Evaluate Bone Mineral Density With Long-Term Use of Relugolix Combination Tablet in Women With Uterine Fibroids or EndometriosisRecruitingNCT05862272Phase 31 country
- CEH-EUS for Differentiating GISTs and Leiomyomas: A Multicenter Prospective Self-Controlled StudyNot yet recruitingNCT071064111 country
- Multicenter Observational Study of Multimodal AI for Upper GI Mesenchymal Tumor DiagnosisRecruitingNCT070781361 country
- Assessment of Tubal Occlusion During Minimally Invasive MyomectomyRecruitingNCT06988774Not applicable1 country
- Effect of Vitamin D3 Supplementation on Symptomatic Uterine Fibroid in Women With Vitamin D DeficiencyRecruitingNCT07012161Early Phase 11 country