Abortion, Spontaneous clinical trials
The registry lists 221 studies for Abortion, Spontaneous across more than 10 countries. 44 are recruiting or about to start. 123 of them are mainly about Abortion, Spontaneous (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 4 narrower conditions too, such as Abortion, Habitual: 388 studies, 80 open.
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Status
Who runs them
University of Pennsylvania (8) · Ain Shams University (5) · Assistance Publique - Hôpitaux de Paris (5) · University Hospital, Montpellier (4) · National Institute of Environmental Health Sciences (NIEHS) (4) · Reprogenetics (4) · Aalborg University Hospital (3) · Chinese University of Hong Kong (3)
What is being tested here
Drugs under test in Abortion, Spontaneous studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Enoxaparin sodium | 2 | 2 | 3 |
| Enoxaparin | 2 | 2 | 3 |
| Misoprostol | 1 | 4 | 17 |
| Letrozole | 1 | 2 | 6 |
| Mifepristone | 1 | 2 | 5 |
| Progesterone | 1 | 1 | 5 |
| Prednisolone | 1 | 0 | 2 |
| Aspirin | 0 | 1 | 3 |
| Immunoglobulins, Intravenous | 0 | 1 | 2 |
| Immunoglobulin G | 0 | 1 | 2 |
Drug classes tested here Progestins 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026Association Between Plasma Level of Mannose Binding Lectin and Human Reproduction · Aalborg University Hospital
- Dec 2026EARLY-PREG: A Preconception Cohort Study Based on Counterfactuals to Study Maternal-Embryonic Molecular Interactions · MELISA Institute Genomics & Proteomics Research SpA
- Dec 2026PERIodontal Disease, Microbiota and Miscarriage · University Hospital, Toulouse
- Dec 2026Machine-Learning Prediction of Pregnancy Outcomes After Assisted Reproductive Treatments · BetaPlus Center for Reproductive Medicine
- Dec 2026Is Decreased Ovarian Reserve Related to an Increased Number of Previous Early Miscarriages? · ART Fertility Clinics LLC
- Dec 2026Physical Activity, Fertility, and Spontaneous Abortion in Danish Couples Trying to Conceive · University of Aarhus
- Jan 2027The Heartland Study · Heartland Health Research Alliance
- Jan 2027Cost-utility Analysis of Outpatient Manual Vacuum Aspiration Versus Operating Room Electric Aspiration for the Management of First-trimester Miscarriage · Nantes University Hospital
- Jan 2027Hysteroscopy for the Diagnosis and Treatment of Pregnancy of Unknown Location · University of Pennsylvania
- Jan 2027GPT-Based Digital Assistant Support During Treatment for Induced Abortion or Missed Abortion · Wolfson Medical Center
Who these studies take
Of the 36 Abortion, Spontaneous studies recruiting now, 11 (31%) set no upper age limit and 25 (69%) stop at 75 or younger. 8 (22%) take children under 18. 30 (83%) are for women only and 0 (0%) for men only; 9 (25%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 4 (11%) | 0 (0%) |
| 18 | 34 (94%) | 6 (17%) |
| 30 | 35 (97%) | 6 (17%) |
| 40 | 35 (97%) | 6 (17%) |
| 50 | 17 (47%) | 3 (8%) |
| 65 | 11 (31%) | 2 (6%) |
| 75 | 11 (31%) | 2 (6%) |
| 85 | 11 (31%) | 2 (6%) |
Across all 221 studies, recruiting or not: 65% stop at 75 or younger and 63% at 65; 17% take children; 90% are for women only and 0% for men only; 35% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Abortion, Spontaneous studies take
Of 45 interventional studies with no phase under Abortion, Spontaneous, half reached primary completion within 27 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 27 mo12–40 · 45 studies | — | 27 mo12–40 · 43 studies |
| Observational | 35 mo17–91 · 43 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered3
- Operative Hysteroscopic Using a Tissue Removal Device for Surgical Management of Early Pregnancy Loss Without Anesthesia - A Pilot StudyNov 10, 2026NCT07929220
- Virtual Reality for Pain and Anxiety During Surgical Uterine Evacuation After Early Pregnancy LossOct 30, 2026NCT07907679
- Evaluation of Assisted Reproductive Technology (ART) Outcomes in Couples With Nonobstructive Azoospermia, Cryptozoospermia, and Severe OligozoospermiaOct 27, 2026NCT07897279
Studies
Recruiting first, then most recently updated. Showing 50 of 221. Browse all 221 → or search them.
- Operative Hysteroscopic Using a Tissue Removal Device for Surgical Management of Early Pregnancy Loss Without Anesthesia - A Pilot StudyNot yet recruitingNCT07929220Not applicable
- Virtual Reality for Pain and Anxiety During Surgical Uterine Evacuation After Early Pregnancy LossNot yet recruitingNCT07907679Not applicable1 country
- Efficacy of Progesterone and Low Molecular Weight Heparin in Recurrent Pregnancy LossNot yet recruitingNCT07796737Phase 31 country
- Optimal Time Interval Between Mifepristone and Misoprostol Administration for Early Pregnancy LossNot yet recruitingNCT07506512Phase 3
- Machine-Learning Prediction of Pregnancy Outcomes After Assisted Reproductive TreatmentsRecruitingNCT078557831 country
- GRACE - Genetic Insights Into Early pRegnancy Loss Using Cell-free fEtal DNARecruitingNCT07639333Not applicable1 country
- GPT-Based Digital Assistant Support During Treatment for Induced Abortion or Missed AbortionNot yet recruitingNCT07856940Not applicable1 country
- Pregnancy in the Context of Urbanicity and Climate Change. The Overall Aim of the Project is to Co-create, Implement, and Test New Clinical Guidelines in Order to Improve the Quality of Care in Antenatal Clinics in the Context of Urbanisation and Climate Change in Dar es Salaam, Tanzania.Enrolling by invitationNCT07751432Not applicable1 country
- Cost-utility Analysis of Outpatient Manual Vacuum Aspiration Versus Operating Room Electric Aspiration for the Management of First-trimester MiscarriageNot yet recruitingNCT07732231Not applicable1 country
- Efficacy of Recombinant Human G-CSF in Women With Unexplained Recurrent MiscarriageRecruitingNCT07724405Phase 21 country
- Using Placental Pathology to Prevent Recurrent Adverse Pregnancy Outcomes: A Pilot ProjectRecruitingNCT06004674Phase 21 country
- Walk With Me (WWM) for Perinatal GriefRecruitingNCT07011940Not applicable1 country
- Is Decreased Ovarian Reserve Related to an Increased Number of Previous Early Miscarriages?RecruitingNCT059695741 country
- Hysteroscopy vs. Endouterine Aspiration in the Management of Trophoblastic RetentionRecruitingNCT05789940Not applicable1 country
- A Multicenter, Prospective, Randomized Controlled Clinical Study on the Effect of Hysteroscopic Uterine Septum Resection on IVF-ET Outcomes in Infertile Patients With Non-recurrent MiscarriageRecruitingNCT07611656Not applicable1 country
- PERIodontal Disease, Microbiota and MiscarriageRecruitingNCT065766221 country
- EARLY-PREG: A Preconception Cohort Study Based on Counterfactuals to Study Maternal-Embryonic Molecular InteractionsRecruitingNCT073580261 country
- Conversational AI Platform for Early Pregnancy Care City-wide Recruitment: A Feasibility StudyRecruitingNCT07197892Not applicable1 country
- Microbiome and Metabolome Profiles in Couples Undergoing IVF and Reproductive OutcomesRecruitingNCT075326291 country
- Determinants of Repeated Spontaneous Miscarriages and Unexplained Fetal DeathsRecruitingNCT04207814Not applicable1 country
- Hysteroscopy for the Diagnosis and Treatment of Pregnancy of Unknown LocationRecruitingNCT07469605Not applicable1 country
- Comparison of Surgical Management of Early Pregnancy Loss by Suction Curettage Versus Hysteroscopy in Patients Undergoing In-vitro Fertilization (IVF)RecruitingNCT07143578Not applicable1 country
- Levothyroxine Treatment and IVF Outcomes in Women With Subclinical Hypothyroidism: A Target Trial EmulationRecruitingNCT072572501 country
- Post-traumatic Stress Disorder in Spontaneous AbortionRecruitingNCT073066761 country
- Cohort of Patients Presenting Unexplained Recurrent Miscarriages and Identification of Early Miscarriage Recidivism FactorsRecruitingNCT055572011 country
- Comprehensive Assessment of First Trimester Pregnancy LossRecruitingNCT072938191 country
- Association Between Plasma Level of Mannose Binding Lectin and Human ReproductionRecruitingNCT051695411 country
- New Cross-linked Hyaluronan Gel to Prevent Adhesion After USG-MVA: RCTRecruitingNCT05360186Not applicable1 country
- Use of Aromatase Inhibitor Before Misoprostol in Medical Termination of MiscarriageRecruitingNCT07109947Not applicable1 country
- The Heartland StudyRecruitingNCT054927081 country
- A Multicenter, Prospective, Randomized, Controlled Clinical Study on the Effect of Hysteroscopic Uterine Septum Resection on the Natural Pregnancy Outcomes in Patients With Non-recurrent Spontaneous AbortionRecruitingNCT07039097Not applicable1 country
- A Prospective Study Evaluating the Impact of Conservative Management on Retained Products of Conception and EMVRecruitingNCT068620891 country
- Ultrasound-guided Manual Vacuum Aspiration (USG-MVA)RecruitingNCT054135251 country
- Effectiveness of Anti-Inflammatory Drugs for Preventing Pain Versus Treating Pain During Medical Abortion From 13 to 22 Weeks at Hung Vuong HospitalRecruitingNCT06696573Not applicable1 country
- Physical Activity, Fertility, and Spontaneous Abortion in Danish Couples Trying to ConceiveRecruitingNCT06705712Not applicable1 country
- Prospective Recurrent Pregnancy Loss RegistryRecruitingNCT059891781 country
- Non-invasive Monitoring of MiscarriageRecruitingNCT065816921 country
- Exploration of Allograft Humoral Rejection in Chronic Histiocytic IntervillositisRecruitingNCT05936333Not applicable1 country
- Genomics and Microbiome Investigation in Cases of Recurrent Pregnancy LossesRecruitingNCT066043381 country
- Prednisolone Administration in Patients With Unexplained REcurrent MIscarriagesRecruitingNCT05725512Phase 41 country
- Machine Learning Miscarriage Management Clinical Decision Support Tool StudyRecruitingNCT063841441 country
- Comprehensive Assessment of Risks for Miscarriage.RecruitingNCT044566601 country
- Prospective Study of BMD and Ca-P Metabolism in RSA Patients: LMWH Use Versus ControlRecruitingNCT058785741 country
- Interest of a Short Early Psychological Care in Women With MiscarriageNot yet recruitingNCT05653414Not applicable
- Factors Influencing Fertility or Pregnancy HealthActive, not recruitingNCT045957601 country
- Evaluation of Assisted Reproductive Technology (ART) Outcomes in Couples With Nonobstructive Azoospermia, Cryptozoospermia, and Severe OligozoospermiaCompletedNCT078972791 country
- Conversational Artificial Intelligence (AI) to Improve PeRiconception Care AccessCompletedNCT06618144Not applicable1 country
- Sperm Selection Strategies and Male-Factor Phenotypes in ICSIActive, not recruitingNCT078255841 country
- Parents' Experience of Child Loss During Pregnancy or BirthCompletedNCT067716611 country
- Letrozole and Misoprostol for Early Pregnancy Loss ManagementCompletedNCT06452719Phase 21 country