SupplementDrug
Betaine clinical trials
Also written Cystadane.
- studies test it
- 26
- open now
- 4
- in phase 3
- 2
- first study started
- 2003
Keep track of what changes. Save the Betaine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
26 studies that test it; most in 2024 (3)
| Year | Studies |
|---|---|
| 2003 | 1 |
| 2006 | 2 |
| 2007 | 1 |
| 2009 | 1 |
| 2010 | 1 |
| 2011 | 2 |
| 2012 | 1 |
| 2013 | 2 |
| 2014 | 2 |
| 2015 | 2 |
| 2016 | 1 |
| 2020 | 1 |
| 2021 | 2 |
| 2023 | 1 |
| 2024 | 3 |
| 2025 | 2 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 1
- Phase 1
- 2
- Phase 2
- 8
- Phase 3
- 2
- Phase 4
- 1
- No phase
- 14
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 0 · Other 26
University of California, San Francisco (3) · Mayo Clinic (2) · Southern California Institute for Research and Education (2) · Fundació Sant Joan de Déu (1) · University of Guelph (1) · Poznan University of Life Sciences (1) · Appalachian State University (1) · Michael J. Ormsbee (1)
Often tested with
Tested in the same studies.
Creatine (2) · Ribavirin (2) · Phosphatidylcholines (1) · Dasatinib (1) · Rabeprazole (1) · Choline (1) · Levomefolate calcium (1) · Vitamin B 12 (1)
Studies
Open first, then newest update. How each study uses Betaine is read from its arms, and is right about nine times in ten.
Testing it · 26
- Betaine vs. Placebo for Serologically Diagnosed Metabolic Dysfunction-associated Steatohepatitis (MASH)Not yet recruitingPhase 2Southern California Institute for Research and EducationNCT07276204Written as Betaine
- Exploratory Study on the Efficacy of Betaine Hydrochloride in Treating Autoimmune GastritisRecruitingNot applicableSecond Affiliated Hospital, School of Medicine, Zhejiang UniversityNCT06881511Written as Oral betaine hydrochloride (2 capsules, 3 times daily)
- A Prospective, Randomized, Open Label Trial of Two Doses of Oral BetaineRecruitingNot applicableSouthern California Institute for Research and EducationNCT03073343Written as Betaine (trimethyglycine)
- The Therapeutic Effect of Betaine in SyringomyeliaRecruitingPhase 2Xuanwu Hospital, BeijingNCT06308367Written as Betaine
- Effect of Betaine and Choline on Metabolic HealthCompletedNot applicableUniversity of GuelphNCT06758856Written as Trimethylglycine
- Maternal Betaine Supplementation During BreastfeedingActive, not recruitingPhase 1/2Fundació Sant Joan de DéuNCT04633044Written as Betaine
- Betaine Supplementation and Lipid Metabolism in Overweight and Obese Pre-menopausal WomenCompletedNot applicablePoznan University of Life SciencesNCT06344377Written as Betaine
- Betaine, Exercise Performance, and Gut PermeabilityCompletedNot applicableAppalachian State UniversityNCT06392360Written as Betaine
- Firefighter Thermoregulatory Responses in Active Fire with Betaine SupplementationCompletedNot applicableMichael J. OrmsbeeNCT06042270Written as Betaine
- The Effects of Pre-Loaded Betaine Supplementation on Thermoregulation and Exercise Metabolism in the HeatCompletedNot applicableFlorida State UniversityNCT04585295Written as Betaine
- Pilot Study of Betaine + Combination Antiviral Therapy for Chronic Hepatitis C Genotype 1 Non-responder/RelapsersTerminatedEarly Phase 1University of NebraskaNCT00882193Written as Betaine
- Potential Synergistic Effect of Combined Blood Flow Restriction Training and Betaine Supplementation on Skeletal MuscleCompletedNot applicableBaylor UniversityNCT05790070Written as Betaine
- Betaine METABOLISM OF PATIENTS With HomocystinuriaCompletedPhase 2Assistance Publique - Hôpitaux de ParisNCT02404337Written as Betaine
- Metabolic Effects of Betaine SupplementationCompletedPhase 2Joslin Diabetes CenterNCT01950039Written as Betaine
- Dietary Supplementation to Increase Serum Choline LevelsCompletedNot applicableUniversity of Colorado, DenverNCT02403804Written as Betaine (588 mg qam and 412 mg qpm)
- Effect of Betaine and Food on Gastric pHCompletedNot applicableUniversity of California, San FranciscoNCT02758015Written as Betaine Hydrochloride 1500mg
- Betaine and Peroxisome Biogenesis DisordersCompletedPhase 3McGill University Health Centre/Research Institute of the McGill University Health CentreNCT01838941Written as Betaine
- Effects of Gastric pH on the Pharmacokinetics of DasatinibCompletedPhase 1University of California, San FranciscoNCT01398046Written as Dasatinib plus Rabeprazole AND Betaine Hydrochloride
- Betaine in Patients With Nonalcoholic SteatohepatitisCompletedPhase 2Mayo ClinicNCT00586911Written as Cystadane
- A Preliminary Study of Choline and Betaine Supplementation Among Adults Exposed to Arsenic in BangladeshCompletedPhase 4Columbia UniversityNCT01749982Written as Betaine
Codes
What other systems call Betaine · ClinicalTrials.gg INT007068
- MeSH (NLM) D001622BetaineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 3SCV180C9WBETAINEConfirmed FDA, NLM, Wikidata
- RxNorm 350374Confirmed FDA, Wikidata
- Wikidata Q10860583betaineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C81038BetaineOne source FDA
- DrugBank DB06756One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D001622 | Betaine | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 3SCV180C9W | BETAINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 350374 | — | Confirmed FDA, Wikidata |
| Wikidata | Q10860583 | betaine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C81038 | Betaine | One source FDA |
| DrugBank | DB06756 | — | One source Wikidata |
Also registered as betaine hydrochloride (UNII JK8U8K4D6K · RxNorm 81965).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.