Dermatomyositis clinical trials
The registry lists 184 studies for Dermatomyositis across more than 10 countries. 63 are recruiting or about to start. 122 of them are mainly about Dermatomyositis (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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A study of drug A after surgery for early breast cancer
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· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Who runs them
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) (8) · National Institute of Environmental Health Sciences (NIEHS) (6) · Chongqing Precision Biotech Co., Ltd (4) · University Hospital, Strasbourg, France (4) · Assistance Publique - Hôpitaux de Paris (4) · Karolinska Institutet (4) · The First Affiliated Hospital with Nanjing Medical University (4) · Pfizer (4)
What is being tested here
Drugs under test in Dermatomyositis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Tocilizumab | 3 | 0 | 4 |
| Dazukibart | 2 | 2 | 4 |
| Tofacitinib | 2 | 0 | 3 |
| Cyclophosphamide | 2 | 0 | 2 |
| Fludarabine | 2 | 0 | 2 |
| Abatacept | 1 | 0 | 4 |
| Baricitinib | 1 | 1 | 3 |
| Sodium thiosulfate | 1 | 1 | 3 |
| Rituximab | 1 | 1 | 3 |
| Infliximab | 1 | 1 | 3 |
Drug classes tested here JAK inhibitors 3 open · Tyrosine kinase inhibitors (TKIs) 3 open · Antimetabolites 3 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 10
- Nov 2026A Study to Evaluate Safety and Efficacy of Empasiprubart in Adults With Dermatomyositis · argenx
- Nov 2026Clinical Study of CD19 Targeted Universal Chimeric Antigen Receptor T Lymphocytes (UCAR-T) for the Treatment of Refractory Juvenile Dermatomyositis (RJDM) · Chongqing Precision Biotech Co., Ltd
- Jan 2027Construction of a Clinico-Imaging Collaborative Diagnostic Model for Dermatomyositis Combined With Interstitial Lung Disease Based on PET/CT Imaging Features and Clinical Parameters · Ruijin Hospital
- Mar 2027Phase 1b Trial of RAY121 in Immunological Diseases (RAINBOW Trial) · Chugai Pharmaceutical
- Apr 2027Phase 2 Trial to Evaluate the Efficacy, Safety of Allogeneic Mitochondria (PN-101) in Patients With Refractory Polymyositis or Dermatomyositis · Paean Biotechnology Inc.
- Apr 2027Study of KYV-101 Anti-CD19 CAR T Therapy in Adult Dermatomyositis · Stanford University
- May 2027A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD5492 in Adult Participants With Systemic Lupus Erythematosus or Idiopathic Inflammatory Myopathies or Rheumatoid Arthritis. · AstraZeneca
- Jul 2027Emapalumab MDA5 Rapidly Progressive Interstitial Lung Disease (RP-ILD) Study · University of Miami
- Jul 2027Clinical Trial of CD19-targeted CAR-T Therapy for Refractory Juvenile Dermatomyositis · Chongqing Precision Biotech Co., Ltd
- Nov 2027Study of NM8074 in Patients with Dermatomyositis (DM) · NovelMed Therapeutics
Who these studies take
Of the 50 Dermatomyositis studies recruiting now, 24 (48%) set no upper age limit and 16 (32%) stop at 75 or younger. 15 (30%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 6 (12%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 13 (26%) | 13 (26%) |
| 18 | 47 (94%) | 47 (94%) |
| 30 | 48 (96%) | 48 (96%) |
| 40 | 48 (96%) | 48 (96%) |
| 50 | 48 (96%) | 48 (96%) |
| 65 | 45 (90%) | 45 (90%) |
| 75 | 36 (72%) | 36 (72%) |
| 85 | 32 (64%) | 32 (64%) |
Across all 184 studies, recruiting or not: 38% stop at 75 or younger and 21% at 65; 33% take children; 1% are for women only and 0% for men only; 11% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Dermatomyositis studies take
Of 19 phase 2 interventional studies under Dermatomyositis, half reached primary completion within 31 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 2 | 31 mo28–52 · 19 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 12, 2026.
Newly registered1
- A Study of BMS-986553 in Participants With Refractory Autoimmune DiseasesOct 14, 2026NCT07873931
Studies
Recruiting first, then most recently updated. Showing 50 of 184. Browse all 184 → or search them.
- FAST for DM - Fatty Acid Supplementation Trial (FAST) for Dermatomyositis (DM)RecruitingNCT07111065Phase 21 country
- A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune DiseaseRecruitingNCT07085104Phase 12 countries
- Natural History of Inflammatory Muscle DiseasesRecruitingNCT057388241 country
- Topical Ruxolitinib Cream for Refractory Cutaneous DermatomyositisRecruitingNCT06857240Phase 21 country
- A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD5492 in Adult Participants With Systemic Lupus Erythematosus or Idiopathic Inflammatory Myopathies or Rheumatoid Arthritis.RecruitingNCT06916806Phase 110 countries
- Environmental Risk Factors for the Anti-synthetase SyndromeRecruitingNCT012764701 country
- A Study to Assess the Long-term Safety and Efficacy of a Subcutaneous Formulation of Efgartigimod in Adults With Active Idiopathic Inflammatory MyopathyEnrolling by invitationNCT05979441Phase 329 countries
- RESET-Myositis: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Idiopathic Inflammatory Myopathy or Juvenile Idiopathic Inflammatory MyopathyRecruitingNCT06154252Phase 2/34 countries
- A Study of BMS-986553 in Participants With Refractory Autoimmune DiseasesNot yet recruitingNCT07873931Phase 16 countries
- Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVORecruitingNCT03816345Phase 12 countries
- A Study to Investigate the Efficacy and Safety of Anifrolumab Administered as Subcutaneous Injection and Added to Standard of Care Compared With Placebo Added to Standard of Care in Adult Participants With Idiopathic Inflammatory Myopathies (Polymyositis and Dermatomyositis)RecruitingNCT06455449Phase 329 countries
- Adult and Juvenile MyositisRecruitingNCT000179141 country
- Subcutaneous Injection of Sodium Thiosulfate for Ectopic Calcifications or Ossifications. A Pilot StudyRecruitingNCT03582800Phase 21 country
- A Study to Understand How the Study Medicine (PF-06823859) Works in People With Active Idiopathic Inflammatory Myopathies [Dermatomyositis (DM) and Polymyositis (PM)]RecruitingNCT05895786Phase 320 countries
- FT839 in Autoimmune DiseasesRecruitingNCT07800871Phase 1/21 country
- A Study to Understand How the Study Medicine Dazukibart Works in People With Idiopathic Inflammatory MyopathiesRecruitingNCT06698796Phase 312 countries
- Emapalumab MDA5 Rapidly Progressive Interstitial Lung Disease (RP-ILD) StudyRecruitingNCT07486869Phase 21 country
- Pain-Sleep in Rheumatic DiseaseNot yet recruitingNCT07775612Not applicable
- BAFF CAR-T Cells (LMY-922) for Treatment of Refractory Autoimmune DiseaseNot yet recruitingNCT07729995Phase 11 country
- Descartes-08 for Children, Adolescents, and Young Adults With Autoimmune DisordersRecruitingNCT07089121Phase 1/21 country
- Phase 1b Trial of RAY121 in Immunological Diseases (RAINBOW Trial)RecruitingNCT06371417Phase 120 countries
- BCMA-CD19 cCAR-T for the Treatment of Refractory Inflammatory MyopathyRecruitingNCT07715136Phase 11 country
- Phase 1b Long-term Extension Trial of RAY121 in Immunological Diseases (RAINBOW-LTE Trial)Enrolling by invitationNCT06723106Phase 119 countries
- A Study of Healthy Donor CD19-targeted Allogeneic CAR T Cells in Participants With Severe, Refractory Autoimmune DiseasesRecruitingNCT07115745Phase 110 countries
- Immunosuppressant Management in Rheumatology Patients Undergoing Elective Total Shoulder ArthroplastyRecruitingNCT07138898Phase 21 country
- Identification of Cutaneous and Blood Biomarkers Predictive of Response to Systemic Treatments During Chronic Inflammatory Skin DiseasesRecruitingNCT065994111 country
- Baricitinib in Patients With Relapsing or naïve DermatomyositisRecruitingNCT04972760Phase 31 country
- Teams Engaged in Accessible Mental Health Interventions for Lupus Erythematosus and Dermatomyositis StressNot yet recruitingNCT06999109Not applicable1 country
- Intralesional Injection of STS in Treatment of CalcinosisRecruitingNCT06672822Phase 21 country
- Exploratory Clinical Study of Anti-CD19/BCMA Universal CAR-T Cell Injection for the Treatment of Refractory Autoimmune DiseasesRecruitingNCT07558850Not applicable1 country
- Safety and Efficacy of ULSC on Disease Severity and Steroid Tapering in Participants With Dermatomyositis/ Polymyositis (DM/PM), Also Known as Idiopathic Inflammatory Myopathy (IIM)RecruitingNCT07160205Phase 2/31 country
- Clinical Responsiveness of Dermatomyositis Using Cutaneous Dermatomyositis Disease Area and Severity Index (CDASI)RecruitingNCT029453451 country
- Clinico-biological Collection of Autoimmune, Dysimmune or Auto-inflammatory Dermatological DiseasesRecruitingNCT063876541 country
- Rheumatology Patient Registry and BiorepositoryRecruitingNCT044020861 country
- A Long-Term Follow-Up Study for Participants Previously Treated With KYV-101RecruitingNCT074031881 country
- RCT of Tocilizumab for Anti-MDA5+DMRecruitingNCT07377058Not applicable1 country
- MIHRA - Patient-Rooted Insights for Shaping Myositis Science (PRISMS)RecruitingNCT073741071 country
- Hypnotherapy for Needle-related Procedural Pain and Anxiety Management in a Pediatric SettingNot yet recruitingNCT07349667Not applicable1 country
- Panniculitis in DermatomyositisRecruitingNCT073459491 country
- Severity Factors of Dermatomyositis in the Caribbean Population - DM-ANTILLESRecruitingNCT072659991 country
- CAR-T Cells in Systemic B Cell Mediated Autoimmune DiseaseRecruitingNCT06347718Phase 1/21 country
- Clinical Study of BCMA/CD70-targeted CAR-T Therapy for Refractory Pediatric Rheumatic DiseasesRecruitingNCT07184450Phase 11 country
- Phase 2 Trial to Evaluate the Efficacy, Safety of Allogeneic Mitochondria (PN-101) in Patients With Refractory Polymyositis or DermatomyositisNot yet recruitingNCT07122648Phase 21 country
- Photoacoustic/Ultrasound Imaging in Patients of Dermatomyositis With Calcinosis Cutis: Characteristic Findings and Treatment Response EvaluationRecruitingNCT07037472Not applicable1 country
- Study of KYV-101 Anti-CD19 CAR T Therapy in Adult DermatomyositisRecruitingNCT06298019Phase 11 country
- Anti-CD19 CAR T-Cell Therapy in Refractory Systemic Autoimmune DiseasesRecruitingNCT06685042Phase 1/21 country
- Study of NM8074 in Patients with Dermatomyositis (DM)Not yet recruitingNCT06887738Phase 2
- Mesenchymal Stem Cells Infusion in Patients With Autoimmune DiseasesEnrolling by invitationNCT06888973Phase 1/21 country
- Home Based Clinical Management of Interstitial Lung Disease in Systemic Rheumatic DiseasesRecruitingNCT06732674Not applicable1 country
- Rheumatology Diet StudyRecruitingNCT063399571 country