Cholinesterase Inhibitors: all 505 studies that test it

Page 1 of 6. Open to participants first (34), then studies with results posted, then the rest; newest registration first within each.

• Pharmacokinetics of Huperzine A Oral Solution in Healthy ParticipantsNot yet recruitingNCT07784335Phase 1
• A Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E2511 in Participants With Early Alzheimer's Disease (AD)Not yet recruitingNCT07768592Phase 1
• A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE)RecruitingNCT07633470Phase 4
• Pilot Study of Galantamine to Treat Metabolic Syndrome in People With Chronic Traumatic Spinal Cord Injury (SCI)RecruitingNCT07625332Phase 2/3
• Evaluation of Echothiophate in Pediatric Patients With Refractory AmblyopiaNot yet recruitingNCT07554131Phase 2
• Antagonism of Neostigmine in Continuous Infusion of MivacuriumNot yet recruitingNCT07524959Not applicable
• Comparing Acotiamide and Itopride for the Management of IndigestionNot yet recruitingNCT07449689Phase 4
• Risk of Acute Complications With Rocuronium vs Cisatracurium in Patients With Chronic Kidney DiseaseRecruitingNCT07203287Phase 4
• Acotiamide vs Itopride in Postprandial Distress SyndromeNot yet recruitingNCT07174297Phase 3
• Exploration of the Efficacy and Mechanism of Galantamine (an Extract From Lycoris Aurea) in Treating Ischemic StrokeRecruitingNCT07003386Phase 2/3
• Prophylactic Intravenous Injection of Neostigmine Plus Atropine Versus Ketorolac on Post-dural Puncture Headache in Patients Undergoing Infraumbilical SurgeriesNot yet recruitingNCT06729047Phase 1/2
• The Study of Ginkgo Leaf Dropping Pills and Huperzine A Injection Combined With Median Nerve Electrical Stimulation in the Treatment of Cognitive Impairment After Brain InjuryRecruitingNCT06704334Phase 4
• Acetylcholinesterase Inhibitor in Anorexia Nervosa: Multicenter, Double-Blind, Placebo-Controlled TrialNot yet recruitingNCT06687993Phase 2
• Comparative Study Between Intrathecal Magnesium Sulfate, Neostigmine and Fentanyl As Adjuvant for Bubivacaine in Postoperative Analgesia in Lower Abdominal SurgeriesNot yet recruitingNCT06685705Phase 4
• An Open Trial of a Novel Pharmacotherapy for Habit Modification in Anorexia NervosaNot yet recruitingNCT06518941Phase 2
• Rivastigmine for Antimuscarinic DeliriumRecruitingNCT06382649Phase 2
• LIFT: Life Improvement TrialRecruitingNCT06366724Phase 2
• Effect of Acetylcholinesterase Inhibitors on Bone MetabolismRecruitingNCT06041789Phase 2
• Pharmacological Reversal of Neuromuscular Blockade in Critically Ill PatientsRecruitingNCT05993390Not applicable
• Potential Benefits of Itopride in the Management of Patients With Metabolic Associated Fatty Liver Disease (MAFLD)Not yet recruitingNCT05966025Phase 2
• Pyridostigmine and Amifampridine for Myasthenia GravisRecruitingNCT05919407Phase 3
• Randomized Clinical Trial of Donepezil for the Treatment of Mild Cognitive Impairment in Parkinson's DiseaseNot yet recruitingNCT05709301Phase 2
• Pyridostigmine for the Treatment of Constipation in Parkinson DiseaseRecruitingNCT05603715Phase 2
• Pyridostigmine Efficacy and Safety for Treatment of Ileus After Colorectal SurgeryRecruitingNCT05334485Phase 2/3
• A Study of Huperzine A Injection in Reducing Postoperative Delirium in Elderly Patients Undergoing Non-cardiac SurgeryRecruitingNCT05242419Not applicable
• Neostigmine and Glycopyrrolate for the Treatment of Headache After Dural PunctureRecruitingNCT05116930Phase 2
• Neostigmine Route for Acute Colonic Pseudo ObstructionRecruitingNCT04951726Phase 4
• Enhancing Parasympathetic Activity to Improve Endothelial Dysfunction, Vascular Oxidative Stress in African AmericansRecruitingNCT04769206Phase 1/2
• Donepezil Versus Non-drug Treatment in Alzheimer's Disease.RecruitingNCT04661280Phase 3
• The Effect of Donepezil on Wound HealingRecruitingNCT04505670Phase 2
• Norfloxacin With Itopride Versus Norfloxacin in Secondary Prophylaxis of Spontaneous Bacterial PeritonitisRecruitingNCT04161768Phase 3
• Comparison of Therapeutic Strategies With Cholinesterase Inhibitors (SOS TRIAL)Not yet recruitingNCT03454646Phase 4
• Early Diagnosis and Early Treatment of Alzheimer's Disease Based on Senile Plaque ImagingNot yet recruitingNCT02931136Phase 4
• A Study of Pyridostigmine in Postural Tachycardia SyndromeRecruitingNCT00409435Phase 2
• Trial of Itopride 150mg Once a Day Versus Itopride 50 mg Thrice a Day; in Patients With Functional DyspepsiaCompletedNCT06217393Phase 3Results posted
• Neuromuscular Blockade Comparison for GI-2 Recovery After Bowel ResectionCompletedNCT06112353Phase 4Results posted
• Postoperative Urinary Retention After Reversal of Neuromuscular Block by Neostigmine Versus SugammadexCompletedNCT05794503Phase 4Results posted
• Postoperative Urinary Retention in Patients After Noncardiac Surgery and Reversal of Neuromuscular BlockCompletedNCT05545280Phase 4Results posted
• Cognition Platform Study in Participants at Risk for Alzheimer's Disease (AD) (MK-0000-413)CompletedNCT04730635Phase 1Results posted
• Pharmacokinetic Study of 5 and 10 mg Corplex™ Donepezil TDS Compared to 10 mg Aricept® in Healthy VolunteersCompletedNCT04617782Phase 1Results posted
• Comparison of Time to Extubation Using Sugammadex or NeostigmineCompletedNCT04606901Phase 4Results posted
• MK-1942/Donepezil Interactions in Participants With Alzheimer's Disease (MK-1942-005)CompletedNCT04308304Phase 1Results posted
• Monitoring Anti-Dementia Drugs by Serum LevelsCompletedNCT04117178Phase 4Results posted
• Role of Sugammadex as Reversal Agent in Patients Extubated Immediately After Isolated Coronary Artery Bypass Grafting SurgeryCompletedNCT03939923Phase 4Results posted
• Effect of Heat on Rivastigmine TDS ProductsCompletedNCT03915626Early Phase 1Results posted
• A Study in Healthy Men and Women to Test Which Effects Donepezil and BI 425809 Have on Each OtherCompletedNCT03905096Phase 1Results posted
• Neuromuscular Blockade in Patients With Severe Renal ImpairmentCompletedNCT03904550Phase 2Results posted
• The Exercise Response to Pharmacologic Cholinergic Stimulation in Myalgic Encephalomyelitis / Chronic Fatigue SyndromeCompletedNCT03674541Phase 2Results posted
• Effect of Galantamine on Inflammation and CognitionCompletedNCT03384784Phase 2Results posted
• Neuromuscular Blockade on Shoulder Pain of ElderlyCompletedNCT03210376Phase 4Results posted
• Study of Recovery of Strength After Surgery Comparing Two Different Medications for Reversal of Muscle RelaxantCompletedNCT03116997Phase 3Results posted
• Use of Sugammadex for Reversal of Paralysis in MicrolaryngoscopyCompletedNCT03111121Phase 4Results posted
• Treatment of Adolescent Antimuscarinic (Anticholinergic) ToxidromeCompletedNCT03090620Phase 4Results posted
• Detecting an Early Response to Donepezil With Measures of Visual AttentionCompletedNCT03073876Phase 4Results posted
• Deep Neuromuscular Block for Laparoscopic SurgeryCompletedNCT03034577Phase 4Results posted
• A Phase IV Study to Evaluate Safety, Tolerability and Effectiveness of Rivastigmine Patch 15cm2 in Patients With Severe Dementia of the Alzheimer's Type.CompletedNCT02989402Phase 4Results posted
• Quality of Recovery After Reversal With Neostigmine or Sugammadex.CompletedNCT02909439Phase 4Results posted
• The Effects of Normalizing Blood Pressure on Cerebral Blood Flow in Hypotensive Individuals With Spinal Cord InjuryCompletedNCT02893553Phase 2Results posted
• Autonomic Neuropathy, GI Motility, and Inflammation in HIVCompletedNCT02850276Early Phase 1Results posted
• Phase 3 Randomized Placebo Controlled Clinical Trial of DonepezilCompletedNCT02822573Phase 3Results posted
• Safety and Efficacy of Donepezil in Mild to Moderate Alzheimer's DiseaseCompletedNCT02787746Phase 4Results posted
• Study of TAK-071 in Healthy Participants and Participants With Mild Cognitive Impairment/Mild Alzheimer Disease and Relative Bioavailability (BA) and Food Effect of TAK-071 in Healthy ParticipantsTerminatedNCT02769065Phase 1Results posted
• NextStep:Study to Evaluate Safety,Efficacy & Tolerability of Rivastigmine Patch in Mild to Moderate Alzheimer's Patients.CompletedNCT02703636Phase 4Results posted
• A Study of Donepezil Hydrochloride in Patients With Dementia Associated With Cerebrovascular DiseaseCompletedNCT02660983Phase 4Results posted
• Investigation of Pharmacokinetic Drug-drug Interaction of BI 409306 and Donepezil in Healthy Male and Female SubjectsCompletedNCT02635750Phase 1Results posted
• A Dose Titration Study of CPC-201 in Patients With Dementia of Alzheimer's TypeCompletedNCT02549196Phase 2Results posted
• Neostigmine Treatment of Acute Pancreatitis Combined With Intra-abdominal HypertensionCompletedNCT02543658Phase 2Results posted
• Pilot Study of Sleep Therapy and Biomarkers in Children With Autism Spectrum DisordersTerminatedNCT02487082Phase 2Results posted
• Low-Dose Galantamine to Potentiate the Attention-Enhancing Effects of Low-Dose NicotineCompletedNCT02420327Not applicableResults posted
• Racial Differences in Vagal Control of Glucose HomeostasisCompletedNCT02365285Phase 1/2Results posted
• Treatment and Prognosis of Neurogenic Orthostatic Hypotension : A Prospective Randomized StudyCompletedNCT02308124Phase 4Results posted
• Acetylcholinesterase Inhibition and Orthostatic Hypotension in SCICompletedNCT02307526Phase 2Results posted
• The Impact of Arousal Threshold in Obstructive Sleep ApneaCompletedNCT02264353Phase 4Results posted
• Cholinesterase Inhibitor DiscontinuationCompletedNCT02248636Phase 2/3Results posted
• Galantamine and Memantine Combination for Cognitive Impairments in SchizophreniaTerminatedNCT02234752Phase 2Results posted
• Effects of Cholinergic Augmentation on Measures of Balance and GaitCompletedNCT02206620Phase 2Results posted
• Safety and Efficacy of Donepezil HCl 23 mg in Patients With Moderate to Severe Alzheimer's DiseaseCompletedNCT02097056Phase 4Results posted
• Effects of Donepezil HCL on Task-Activated fMRI Brain Activation in Healthy Older Adults at Genetic Risk for Alzheimer's DiseaseCompletedNCT02087865Phase 4Results posted
• Computerized Cognition Testing in Participants With Mild Alzheimer's Disease (AD) Treated With Donepezil (MK-0000-318)CompletedNCT02064920Phase 2Results posted
• Roflumilast and Donepezil to Reverse Scopolamine Induced Cognitive Deficits in Healthy AdultsCompletedNCT02051335Phase 1Results posted
• Acetylcholine, Tobacco Smoking, Genes and Nicotinic ReceptorsCompletedNCT02008292Not applicableResults posted
• Recovery of Diaphragmatic Function After Neuromuscular Blockade and SugammadexCompletedNCT01962298Phase 3Results posted
• Olfactory Deficits and Donepezil Treatment in Cognitively Impaired ElderlyCompletedNCT01951118Phase 4Results posted
• 16w Interventional Study on Titration and Dose/Efficacy Assessment of Exelon in Chinese Alzheimer's Disease PatientsCompletedNCT01948791Phase 4Results posted
• A Trial of the Drug Donepezil for Sleep Enhancement and Behavioral Change in Children With AutismTerminatedNCT01887132Phase 2Results posted
• A Study to Help People Quit Smoking.CompletedNCT01880099Not applicableResults posted
• Olfactory Deficits in MCI as Predictor of Improved Cognition on DonepezilCompletedNCT01845636Phase 4Results posted
• Donepezil Compared to Placebo in Patients With Chronic Neuropathic PainTerminatedNCT01743976Phase 4Results posted
• Pharmacokinetic Study of Deferiprone in Paediatric PatientsCompletedNCT01740713Phase 2Results posted
• Effects of Huperzine A in Treatment of Moderate to Severe TBITerminatedNCT01676311Phase 2Results posted
• Rivastigmine Patch in Veterans With Cognitive Impairment Following TBICompletedNCT01670526Phase 3Results posted
• Effect of Galantamine on Short-term AbstinenceCompletedNCT01669538Phase 2Results posted
• Combination Treatment Study for Memory Impairment and DepressionCompletedNCT01658228Phase 4Results posted
• Study of Exelon Transdermal Patch in Amnestic Mild Cognitive Impairment PatientsTerminatedNCT01602198Not applicableResults posted
• Tolerability of Rivastigmine Before and After Switching From Oral Formulation to Transdermal Patch in Alzheimer's DementiaCompletedNCT01585272Phase 4Results posted
• Effect of Galantamine on Smoking AbstinenceCompletedNCT01548638Phase 2Results posted
• Cognitive Enhancement as a Target for Cocaine PharmacotherapyCompletedNCT01531153Not applicableResults posted
• The Effect of Donepezil on Gait and Balance in Parkinson's DiseaseCompletedNCT01521117Phase 4Results posted
• Mild Cognitive Impairment in Parkinson's DiseaseCompletedNCT01519271Phase 4Results posted
• Study of Donepezil in Female Breast Cancer Survivors With Cognitive DysfunctionCompletedNCT01466270Phase 2Results posted

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