Brexpiprazole: all 79 studies that test it

Page 1 of 1. Open to participants first (4), then studies with results posted, then the rest; newest registration first within each.

• Longitudinal PET Imaging of Antipsychotic Binding to the Dopamine-3 Receptor in SchizophreniaNot yet recruitingNCT07715253Phase 1
• Optimized Predictive Treatment In Medications for Unipolar Major Depression (OPTIMUM-D)RecruitingNCT05017311Phase 4
• Brexpiprazole Treatment for Bipolar I DepressionRecruitingNCT04569448Phase 3
• Brexpiprazole in Alcohol Use DisorderRecruitingNCT04066192Phase 2
• Brexpiprazole as Adjunctive Therapy in Adults With Major Depressive DisorderCompletedNCT04830215Phase 4Results posted
• Brexpiprazole in Treatment of Children and Adolescents With Irritability Associated With Autism Spectrum Disorder for Subjects That Have Completed Participation in 331-201-00148CompletedNCT04258839Phase 3Results posted
• Evaluating the Safety and Tolerability of Brexpiprazole in the Treatment of Adults With Borderline Personality Disorder (BPD)CompletedNCT04186403Phase 2/3Results posted
• Brexpiprazole in Treatment of Children and Adolescents With Irritability Associated With Autism Spectrum DisorderCompletedNCT04174365Phase 3Results posted
• Brexpiprazole as Combination Therapy With Sertraline in the Treatment of Adults With Post-traumatic Stress DisorderCompletedNCT04174170Phase 3Results posted
• Brexpiprazole as Combination Therapy With Sertraline in Treatment of Adults With PTSDCompletedNCT04124614Phase 3Results posted
• A Trial of Brexpiprazole in the Treatment of Borderline Personality DisorderCompletedNCT04100096Phase 2Results posted
• A Long-Term Study of Brexpiprazole in Patients With Major Depressive DisorderCompletedNCT03737474Phase 3Results posted
• Brexpiprazole for the Long-term Treatment of Patients With Agitation Associated With Dementia of the Alzheimer's TypeCompletedNCT03724942Phase 3Results posted
• A Study of Brexpiprazole in Patients With Major Depressive DisorderCompletedNCT03697603Phase 2/3Results posted
• Brexpiprazole for the Treatment of Patients With Agitation Associated With Dementia of the Alzheimer's TypeCompletedNCT03620981Phase 2/3Results posted
• A 12-week Extension Trial to Evaluate the Safety and Tolerability of Brexpiprazole in the Treatment of Subjects With Agitation Associated With Dementia of the Alzheimer's TypeCompletedNCT03594123Phase 3Results posted
• A Trial to Evaluate the Safety, Efficacy, and Tolerability of Brexpiprazole in Treating Agitation Associated With Dementia of the Alzheimer's TypeCompletedNCT03548584Phase 3Results posted
• A Trial to Evaluate the Efficacy, Safety & Tolerability of Brexpiprazole in the Maintenance Treatment of Adults With Major Depressive DisorderCompletedNCT03538691Phase 3Results posted
• Controlled Trial of Brexpiprazole For The Treatment of Co-occurring Schizophrenia and Substance Use DisorderCompletedNCT03526354Phase 4Results posted
• Brexpiprazole for Bipolar DepressionCompletedNCT03427892Phase 4Results posted
• Brexpiprazole in Borderline Personality DisorderCompletedNCT03418675Phase 2Results posted
• A Trial to Evaluate the Safety and Tolerability of Brexpiprazole in the Treatment of Participants With Bipolar I Disorder.CompletedNCT03287869Phase 3Results posted
• A Trial to Assess Brexpiprazole Versus Placebo for the Treatment of Acute Manic Episodes Associated With Bipolar I DisorderCompletedNCT03259555Phase 3Results posted
• A Trial to Assess Brexpiprazole Versus Placebo for the Treatment of Acute Manic Episodes, Associated With Bipolar I DisorderCompletedNCT03257865Phase 3Results posted
• Safety and Tolerability of Open-Label Flexible-dose Brexpiprazole as Maintenance Treatment in Adolescents With SchizophreniaCompletedNCT03238326Phase 3Results posted
• Trial to Evaluate the Short-term Safety & Efficacy of Brexpiprazole Monotherapy in the Treatment of Adolescents With SchizophreniaCompletedNCT03198078Phase 3Results posted
• A Study of Brexpiprazole Plus Ketamine in Treatment-Resistant Depression (TRD)CompletedNCT03149991Phase 4Results posted
• A Study of Flexible Dose Brexpiprazole as Monotherapy or Combination Therapy in the Treatment of Adults With Post-traumatic Stress Disorder (PTSD)CompletedNCT03033069Phase 2Results posted
• A Pilot Dose-Response Biomarker Study of Brexpiprazole Treatment in PTSDTerminatedNCT02934932Phase 2Results posted
• Evaluation Study of the Bioavailability of Brexpiprazole Orally Disintegrating Tablets in Healthy Male SubjectsCompletedNCT02875080Phase 1Results posted
• Study of the Safety and Efficacy of Fixed-dose Brexpiprazole (OPC-34712) as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder With and Without Anxious DistressCompletedNCT02196506Phase 3Results posted
• Monotherapy Brexpiprazole (OPC-34712) Trial in the Treatment of Adults With Schizophrenia With ImpulsivityCompletedNCT02194933Phase 3Results posted
• Brexpiprazole (OPC-34712) Trial in the Treatment of Adults With Acute SchizophreniaCompletedNCT02054702Phase 3Results posted
• Monotherapy Brexpiprazole (OPC-34712) Trial in the Treatment of Adults With Early-Episode SchizophreniaCompletedNCT02013622Phase 3Results posted
• Brexpiprazole (OPC-34712) as an Adjunctive Treatment in Active Adults, 18 to 35 Years Old, With Major Depressive Disorder Who Are in a School or Work EnvironmentCompletedNCT02013609Phase 3Results posted
• Brexpiprazole (OPC-34712) as an Adjunctive Treatment in Adults With Major Depressive Disorder and Anxiety SymptomsCompletedNCT02013531Phase 3Results posted
• Brexpiprazole as Adjunctive Therapy With Major Depressive Disorder and an Inadequate Response to Previous Adjunctive TherapyCompletedNCT02012218Phase 3Results posted
• Brexpiprazole as an Adjunctive Treatment to Paroxetine or Sertraline in Adult Patients Suffering From Post-traumatic Stress Disorder (PTSD)TerminatedNCT01987960Phase 3Results posted
• Long-term Safety and Tolerability Study of Brexpiprazole as Adjunctive Treatment in Patients With Major Depressive DisorderTerminatedNCT01944969Phase 3Results posted
• Study of Brexpiprazole as Adjunctive Treatment of Irritability in Patients With Major Depressive Disorder and an Inadequate Response to Antidepressant TherapyCompletedNCT01942785Phase 3Results posted
• Study of Brexpiprazole as Adjunctive Treatment of Sleep Disturbances in Patients With Major Depressive DisorderCompletedNCT01942733Phase 3Results posted
• Safety and Tolerability Study of Flexible Dosing of Brexpiprazole in the Treatment of Subjects With Agitation Associated With Dementia of the Alzheimer's TypeCompletedNCT01922258Phase 3Results posted
• A Phase 3, 12-week, Multicenter, Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Efficacy, Safety, and Tolerability of 2 Fixed Doses of Brexpiprazole in the Treatment of Alzheimer's AgitationCompletedNCT01862640Phase 3Results posted
• PET Trial to Assess the Receptor Occupancy of Brexpiprazole in Adult Subjects With SchizophreniaCompletedNCT01854944Phase 1Results posted
• Brexpiprazole as Adjunctive Treatment in Patients With Major Depressive Disorder With an Inadequate Response to Antidepressant TreatmentCompletedNCT01838681Phase 3Results posted
• Efficacy and Safety of Brexpiprazole as Adjunctive Treatment in Elderly Patients With Major Depressive Disorder With an Inadequate Response to Antidepressant TreatmentTerminatedNCT01837797Phase 3Results posted
• Brexpiprazole in Patients With SchizophreniaCompletedNCT01810783Phase 3Results posted
• Brexpiprazole in Patients With Acute SchizophreniaCompletedNCT01810380Phase 3Results posted
• A Study of Flexible-dose Brexpiprazole as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder, the Delphinus TrialCompletedNCT01727726Phase 3Results posted
• Phase 1 Study to Assess the Safety/Tolerability of Brexpiprazole as Adjunctive Therapy in Elderly Subjects With Major Depressive DisorderCompletedNCT01670279Phase 1Results posted
• Efficacy, Safety, and Tolerability of Brexpiprazole (OPC-34712) as Maintenance Treatment in Adults With SchizophreniaCompletedNCT01668797Phase 3Results posted
• Multicenter, Open-label, Safety and Tolerability StudyCompletedNCT01649557Phase 2Results posted
• A Long-term Trial of OPC-34712 in Patients With SchizophreniaCompletedNCT01456897Phase 3Results posted
• A Dose-finding Trial of OPC-34712 in Patients With SchizophreniaCompletedNCT01451164Phase 2/3Results posted
• Study of Safety & Tolerability of OPC-34712 as Adjunctive Therapy in Treatment of Adult Patients With Major Depressive DisorderCompletedNCT01447576Phase 2Results posted
• Trial to Evaluate the Effects of OPC-34712 on QT/QTc in Subjects With Schizophrenia or Schizoaffective DisorderCompletedNCT01423916Phase 1Results posted
• Safety and Tolerability Study of Oral OPC-34712 as Maintenance Treatment in Adults With SchizophreniaCompletedNCT01397786Phase 3Results posted
• Study of the Effectiveness of Three Different Doses of OPC-34712 in the Treatment of Adults With Acute SchizophreniaCompletedNCT01396421Phase 3Results posted
• Efficacy Study of OPC-34712 in Adults With Acute SchizophreniaCompletedNCT01393613Phase 3Results posted
• Study of the Safety and Efficacy of Fixed Dose OPC-34712 as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder (the Pyxis Trial)CompletedNCT01360645Phase 3Results posted
• Study of the Safety and Efficacy of Two Fixed Doses of OPC-34712 as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder (the Polaris Trial)CompletedNCT01360632Phase 3Results posted
• A Study Evaluating the of OPC-34712 in Subjects With Normal Hepatic Function and Hepatically Impaired SubjectsCompletedNCT01299454Phase 1Results posted
• Trial Evaluating OPC-34712 in Subjects With Normal Renal Function and Renally Impaired SubjectsCompletedNCT01289080Phase 1Results posted
• Study of the Safety and Efficacy of OPC-34712 as a Complementary Therapy in the Treatment of Adult Attention Deficit/Hyperactivity DisorderCompletedNCT01074294Phase 2Results posted
• Study of the Safety and Efficacy of OPC-34712 as Adjunctive Therapy in the Treatment of Adults With Major Depressive DisorderCompletedNCT01052077Phase 2Results posted
• Study to Evaluate the Efficacy, Safety, and Tolerability of Oral OPC-34712 and Aripiprazole for Treatment of Acute SchizophreniaCompletedNCT00905307Phase 2Results posted
• Study of the Safety and Efficacy of OPC-34712 as Adjunctive Therapy in the Treatment of Patients With Major Depressive DisorderCompletedNCT00797966Phase 2Results posted
• Bioequivalence Study to Compare Brexpiprazole 4 mg Film Coated Tablets Versus RXULTI 4 mg Film Coated Tablet (Brexpiprazole)CompletedNCT07266792Phase 1
• Open-label Brexpiprazole fMRI Trial in Adults With Major Depressive Disorder and AnxietyWithdrawnNCT05504486Phase 4
• Canadian Biomarker Integration Network for Depression (CAN-BIND) - Validation StudyCompletedNCT04162522Phase 3
• Safety and Efficacy of Brexpiprazole in the Treatment of SchizophreniaCompletedNCT03874494Phase 3
• The Pharmacokinetics, Tolerability and Safety of Brexpiprazole in Healthy Chinese SubjectsCompletedNCT03734354Phase 1
• The Pharmacokinetics, and Safety of Brexpiprazole Tablets in Chinese Healthy SubjectsCompletedNCT03734302Phase 1
• The Safety and Efficacy of Brexpiprazole as Adjunctive Therapy in the Treatment of Major Depressive DisorderTerminatedNCT03487198Phase 3
• Trial to Assess the Pharmacokinetics, Safety, Tolerability of Oral Brexpiprazole in Children (6 to <13 Years Old) With Central Nervous System DisordersCompletedNCT03292848Phase 1
• Comparison of the Effectiveness of Brexpiprazole With That of RisperidoneWithdrawnNCT02758067Phase 3
• Study to Assess the Safety, Tolerability and Pharmacokinetics of Oral Brexpiprazole (OPC- 34712) in Adolescents With SchizophreniaCompletedNCT02411695Phase 1
• Brexpiprazole (OPC 34712) Trial in the Treatment of Adults With Major Depressive Disorder and IrritabilityWithdrawnNCT02212613Phase 3
• Positron Emission Tomagraphy (PET) Study Following a Single Oral Dose of OPC-34712CompletedNCT00805454Phase 1

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