An interventional study of surgical depigmentation and Coenzyme Q10 in Depigmentation Treatment and Depigmentation, sponsored by Al-Azhar University. Recruiting at 1 site in Egypt. Open to participants aged 18 Years to 45 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-07-01.
Sponsored by Al-Azhar University · Not applicable, Interventional, and Treatment
This study aims to assess the clinical effectiveness of Co-enzyme Q10 and Vitamin C, applied individually or in combination after surgical gingival depigmentation.
343 studies on the registry are indexed under Vitiligo; 96 are open to participants now.
This study's planned enrollment of 20 is below the median of 36 across 265 interventional studies indexed under Vitiligo.
Browse Vitiligo studies →Al-Azhar University is the lead sponsor of 531 studies on the registry; 172 are open to participants now.
Of its 5 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
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Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
An allergy, or another reaction of the immune system, to a substance. “Hypersensitivity to the study drug” means a known allergic reaction to it — not every side effect a medicine can have.
Hypersensitivity
An allergy, or another reaction of the immune system, to a substance. “Hypersensitivity to the study drug” means a known allergic reaction to it — not every side effect a medicine can have.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Surgical Depigmentation Alone
Procedure: surgical depigmentation
Surgical Depigmentation + CoQ10
Procedure: surgical depigmentation · Dietary Supplement: Coenzyme Q10
Surgical Depigmentation + Vitamin C
Procedure: surgical depigmentation · Dietary Supplement: Vitamin C
Surgical Depigmentation + CoQ10 + Vitamin C
Procedure: surgical depigmentation · Dietary Supplement: Surgical Gingival Depigmentation Coenzyme Q10 Vitamin C
Surgical gingival depigmentation performed using the conventional scalpel technique. The pigmented gingival epithelium is surgically removed under local anesthesia to eliminate melanin pigmentation and improve gingival esthetics.
Coenzyme Q10 administered according to the study protocol following surgical gingival depigmentation to evaluate its effect on wound healing and gingival depigmentation.
Vitamin C administered according to the study protocol following surgical gingival depigmentation to evaluate its effect on wound healing and gingival depigmentation.
Coenzyme Q10 and vitamin c administered according to the study protocol following surgical gingival depigmentation to evaluate its effect on wound healing and gingival repigmentation.
Change in gingival pigmentation intensity using the Dummett Oral Pigmentation Index (DOPI). The DOPI scale from 0 to 3, where:0 = No clinical pigmentation ,1 = Mild pigmentation , 2 = Moderate pigmentation 3 = Heavy pigmentation
Change in gingival pigmentation intensity that measured by using a standardized gingival pigmentation index (DOPI)
Time frame: 1 week, 1 month and 3 months. ,6 months
Plan to share: No
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Studies of the drugs tested here: Coenzyme Q10 · Ascorbic Acid