Drug
Arsenic Trioxide clinical trials
Also written Trisenox and Arsenic Sesquioxide.
- studies test it
- 118
- open now
- 14
- in phase 3
- 8
- first study started
- 1997
Keep track of what changes. Save the Arsenic Trioxide studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
116 studies that test it; most in 2004 (14)
| Year | Studies |
|---|---|
| 1997 | 1 |
| 1998 | 3 |
| 1999 | 1 |
| 2000 | 13 |
| 2001 | 5 |
| 2002 | 8 |
| 2003 | 5 |
| 2004 | 14 |
| 2005 | 7 |
| 2006 | 1 |
| 2007 | 9 |
| 2008 | 4 |
| 2009 | 2 |
| 2010 | 3 |
| 2011 | 5 |
| 2013 | 4 |
| 2014 | 1 |
| 2015 | 1 |
| 2016 | 3 |
| 2017 | 2 |
| 2018 | 4 |
| 2019 | 1 |
| 2020 | 3 |
| 2021 | 3 |
| 2022 | 1 |
| 2023 | 2 |
| 2024 | 1 |
| 2025 | 5 |
| 2026 | 4 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 2
- Phase 1
- 40
- Phase 2
- 76
- Phase 3
- 8
- Phase 4
- 2
- No phase
- 4
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 10 · Other 108
Memorial Sloan Kettering Cancer Center (10) · National Cancer Institute (NCI) (6) · M.D. Anderson Cancer Center (4) · Northwestern University (4) · Stanford University (3) · University of Miami (3) · The University of Texas Medical Branch, Galveston (3) · CTI BioPharma (3)
Often tested with
Tested in the same studies.
Ascorbic Acid (13) · Tretinoin (10) · Dexamethasone (6) · Thalidomide (5) · Cytarabine (5) · Decitabine (4) · Gemtuzumab (3) · Imatinib (3)
Studies
Open first, then newest update. How each study uses Arsenic Trioxide is read from its arms, and is right about nine times in ten.
Testing it · 118
- Arsenic Trioxide Combined With Chemotherapy for Relapsed SHH-Activated and/or TP53-Mutant MedulloblastomaNot yet recruitingPhase 2Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityNCT07856069Written as Arsenic Trioxide (ATO)
- Oral Arsenic (ATO) in Low-risk Myelodysplastic Syndromes (MDS)RecruitingPhase 1Groupe Francophone des MyelodysplasiesNCT06670222Written as Arsenic Trioxide (ATO)
- Arsenic Trioxide to Prevent Relapse in Patients Undergoing Allogeneic Stem Cell Transplantation for Acute Myeloid Leukemia or Myelodysplastic SyndromeNot yet recruitingPhase 1University of Michigan Rogel Cancer CenterNCT07737769Written as Arsenic Trioxide
- Tretinoin and Arsenic Trioxide With or Without Gemtuzumab Ozogamicin in Treating Patients With Previously Untreated Acute Promyelocytic LeukemiaRecruitingPhase 2M.D. Anderson Cancer CenterNCT01409161Written as Arsenic Trioxide
- ATRA and SDK002 in Combination With Chemotherapy and Anti-PD-1 Inhibitor in Patients With Advanced Pancreatic Ductal Adenocarcinoma.Not yet recruitingPhase 1Daniel BreadnerNCT07348107Written as Arsenic Trioxide (ATO)
- A Trial to Investigate Whether Oral Arsenic Trioxide Is Similar to Intravenous Arsenic Trioxide in Pharmacokinetics, Safety, and Efficacy (LATITUDE/SDKARS-301)Not yet recruitingPhase 3SDK Therapeutics, Inc.NCT07296445Written as IV Arsenic Trioxide
- Oral-ATO for TP53-mutated Myeloid MalignanciesRecruitingPhase 2The University of Hong KongNCT06778187Written as Oral arsenic trioxide
- Efficacy and Safety of ATO Plus ATRA in Nucleophosmin-1 Mutated Acute Myeloid LeukemiaEnrolling by invitationPhase 1/2Institute of Hematology & Blood Diseases Hospital, ChinaNCT03031249Written as Arsenic Trioxide
- Arsenic Trioxide With MAPK Inhibitors and Chemotherapy for Stage 4/M NeuroblastomaRecruitingPhase 2Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityNCT06933394Written as Arsenic trioxide
- Fuzuloparib Arsenic Trioxide Platinum Resistance Relapsed Ovarian CancerRecruitingPhase 1/2Xing XieNCT04518501Written as Arsenic trioxide Tablet +Fuzuloparib Capsules
- Evaluate the Efficacy and Safety of Interferon-α Combined With ATO in the Treatment of Arsenic-resistant APLRecruitingNot applicableZhejiang Provincial People's HospitalNCT06450145Written as interferon α-2b
- Arsenic Trioxide Combined With Chemotherapy for the Treatment of p53-mutated Pediatric CancerRecruitingPhase 2Yang LiNCT06088030Written as Arsenic trioxide
- Effectiveness and Safety of Therapy Based on Attenuated ATO Plus Low-Dose ATRA in Patients With APLRecruitingPhase 1/2Hospital Universitario Dr. Jose E. GonzalezNCT05497310Written as Arsenic trioxide
- The Effect of Arsenic Trioxide on Eliminating HIV-1 Reservoir Combined With cARTRecruitingPhase 1Guangzhou 8th People's HospitalNCT03980665Written as Arsenic Trioxide
- Study for Patients With Newly Diagnosed, High-risk Acute Promyelocytic LeukemiaCompletedPhase 3Technische Universität DresdenNCT02688140Written as Arsenic trioxide
- Tretinoin and Arsenic Trioxide in Treating Patients With Untreated Acute Promyelocytic LeukemiaActive, not recruitingPhase 3Children's Oncology GroupNCT02339740Written as Arsenic Trioxide
- Evaluate the Pharmacokinetics of Oral Arsenic Trioxide Solution Under Fasting and Fed Conditions, to Compare Intravenous Arsenic Trioxide, in Acute Promyelocytic LeukemiaCompletedPhase 1SDK Therapeutics, Inc.NCT06882031Written as Treatment A: Arsenic Trioxide (ATO) Intravenous
- Venetoclax Combined With ATRA and ATO in Hyperleukocytic Acute Promyelocytic LeukemiaActive, not recruitingNot applicableAnhui Medical UniversityNCT07187505Written as Arsenic Trioxide (ATO)
- Phase II Study of Combined Chemotherapy With Arsenic Trioxide in Stage 4/M NeuroblastomaActive, not recruitingPhase 2Yang LiNCT03503864Written as Arsenic Trioxide
- A Study for Oral SY-2101 for Participants With Acute Promyelocytic LeukemiaSuspendedPhase 1Syros PharmaceuticalsNCT04996030Written as SY-2101
See all 118 studies that test Arsenic Trioxide →
Given in every arm · 8 — Arsenic Trioxide is usual care beside what is tested
- Early Use of Realgar-Indigo Naturalis Formula (RIF) Combined With All-trans Retinoic Acid (ATRA) for Treating Acute Promyelocytic Leukemia (APL).RecruitingPhase 3First Affiliated Hospital Xi'an Jiaotong UniversityNCT07503730Written as ATO
- Treatment Study for Children and Adolescents With Acute Promyelocytic LeukemiaRecruitingPhase 2Associazione Italiana Ematologia Oncologia PediatricaNCT04793919Written as Arsenic Trioxide
- Treatment of Acute Myeloid Leukemia With Arsenic and All-trans Retinoid AcidStatus unknownPhase 1First Affiliated Hospital Xi'an Jiaotong UniversityNCT05297123Written as Arsenic Trioxide
- Leukemia SPORE Phase II DAC Study for R/R and Elderly Acute AML and MDSCompletedPhase 2Fox Chase Cancer CenterNCT02190695Written as Arsenic trioxide
- Velcade, Trisenox, Vitamin C and Melphalan for Myeloma PatientsCompletedPhase 1/2M.D. Anderson Cancer CenterNCT00469209Written as Trisenox (Arsenic Trioxide)
- All-trans Retinoic Acid, and Arsenic +/- IdarubicinCompletedPhase 2M.D. Anderson Cancer CenterNCT00413166Written as Arsenic Trioxide (ATO)
- Tretinoin, Cytarabine, and Daunorubicin Hydrochloride With or Without Arsenic Trioxide Followed by Tretinoin With or Without Mercaptopurine and Methotrexate in Treating Patients With Acute Promyelocytic LeukemiaCompletedPhase 3National Cancer Institute (NCI)NCT00003934Written as arsenic trioxide
- Arsenic Trioxide With or Without Tretinoin in Treating Patients With Hematologic Cancer That Has Not Responded to Previous TherapyTerminatedPhase 1/2Washington University School of MedicineNCT00006220Written as arsenic trioxide
As the comparator · 3 — what is tested is compared with Arsenic Trioxide
- Pivotal Open-label Phase 3 Clinical Study of QTX-2101 in Adult Patients With Acute Promyelocytic LeukemiaRecruitingPhase 3Quetzal TherapeuticsNCT07504458Written as IV arsenic trioxide (ATO) + ATRA
- A Study for Improving the Outcome of Childhood Acute Promyeloid LeukemiaCompletedPhase 4South China Children's Leukemia GroupNCT02200978Written as ATO
- Treatment of Non-high-risk Acute Promyelocytic Leukemia (APL) With Realgar-Indigo Naturalis Formula (RIF)Status unknownPhase 3First Affiliated Hospital Xi'an Jiaotong UniversityNCT02899169Written as Arsenic trioxide
Codes
What other systems call Arsenic Trioxide · ClinicalTrials.gg INT006674
- MeSH (NLM) D000077237Arsenic TrioxideConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) S7V92P67HOARSENIC TRIOXIDEConfirmed FDA, NLM, Wikidata
- RxNorm 18330Confirmed FDA, Wikidata
- Wikidata Q7739arsenic trioxideConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C1005Arsenic TrioxideConfirmed FDA, Wikidata
- DrugBank DB01169One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000077237 | Arsenic Trioxide | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | S7V92P67HO | ARSENIC TRIOXIDE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 18330 | — | Confirmed FDA, Wikidata |
| Wikidata | Q7739 | arsenic trioxide | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C1005 | Arsenic Trioxide | Confirmed FDA, Wikidata |
| DrugBank | DB01169 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.