Urethral Stricture clinical trials
The registry lists 72 studies for Urethral Stricture across more than 10 countries. 25 are recruiting or about to start. 67 of them are mainly about Urethral Stricture (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-03.
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Who runs them
University Hospital, Ghent (7) · Urotronic Inc. (5) · Ain Shams University (5) · Al-Azhar University (3) · Tanta University (2) · University of California, San Francisco (2) · University of Roma La Sapienza (2) · Sohag University (1)
What is being tested here
Drugs under test in Urethral Stricture studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 10
- Nov 2026Outcomes of Double-face Augmentation Urethroplasty · Menoufia University
- Jan 2027Treatment of Bulbar Urethral Strictures With Optilume Drug-Coated Balloons in an Untreated Population · Aalborg University Hospital
- Feb 2027Urethral Resistive Index (URI): A New Parameter for Diagnosing Urethral Obstruction · Ankara City Hospital Bilkent
- Mar 2027Early vs Late Urinary Catheter Removal After Renal Transplantation · Medical University of Warsaw
- Jun 2027Optilume PoST AppRoval Clinical Evaluation of Andrology ParaMeters · Urotronic Inc.
- Aug 2027Comparison Between Excision And Primary Anastomosis Urethroplasty And Tunica Vaginalis Graft Urethroplasty. · Sahiwal medical college sahiwal
- Aug 2027LishitonglinUS-01 Trial · Peking University First Hospital
- Sep 2027Optimal Duration of Foley Catheter After Bulbar Urethroplasty · Jane Kurtzman
- Oct 2027Observational Study of the LambdaGuide System for Measurement of Observable Genitourinary Anatomy During Cystoscopic Procedures in Men · Lambda Surgical, Inc
- Nov 2027Safety and Potential Effect of Innovative Treatment by Adjuvant Injection of Stromal Vascular Fraction From Autologous Adipose Tissue of URethral Stenosis With Endoscopic Urethrotomy · Assistance Publique Hopitaux De Marseille
Who these studies take
Of the 15 Urethral Stricture studies recruiting now, 11 (73%) set no upper age limit and 1 (7%) stop at 75 or younger. 3 (20%) take children under 18. 0 (0%) are for women only and 13 (87%) for men only; 2 (13%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (7%) | 3 (20%) |
| 18 | 2 (13%) | 13 (87%) |
| 30 | 2 (13%) | 15 (100%) |
| 40 | 2 (13%) | 15 (100%) |
| 50 | 2 (13%) | 15 (100%) |
| 65 | 2 (13%) | 15 (100%) |
| 75 | 2 (13%) | 15 (100%) |
| 85 | 2 (13%) | 13 (87%) |
Across all 72 studies, recruiting or not: 21% stop at 75 or younger and 10% at 65; 14% take children; 1% are for women only and 88% for men only; 10% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Urethral Stricture studies take
Of 24 interventional studies with no phase under Urethral Stricture, half reached primary completion within 40 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 40 mo23–64 · 24 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered2
Studies
Recruiting first, then most recently updated. Showing 50 of 72. Browse all 72 → or search them.
- Urethral Resistive Index (URI): A New Parameter for Diagnosing Urethral ObstructionRecruitingNCT074037861 country
- Observational Study of the LambdaGuide System for Measurement of Observable Genitourinary Anatomy During Cystoscopic Procedures in MenRecruitingNCT079123851 country
- Intraoperative Lidocaine or Dexmedetomidine for Postoperative Pain Modulation After Urethral Reconstruction.RecruitingNCT07676942Not applicable1 country
- REDUCER Trial (TXA in Urethroplasty)Not yet recruitingNCT07501884Phase 41 country
- Comparison Between Excision And Primary Anastomosis Urethroplasty And Tunica Vaginalis Graft Urethroplasty.Not yet recruitingNCT07668973Not applicable
- Safety and Feasibility Study of Autologous Engineered Urethral Constructs for the Treatment of StricturesRecruitingNCT03258658Phase 11 country
- A Comparative Study of the Antibacterial Effects of Two Preoperative Hair Removal Methods in Male Patients With Urethral StrictureNot yet recruitingNCT07508566Not applicable
- Optimal Duration of Foley Catheter After Bulbar UrethroplastyEnrolling by invitationNCT07220980Not applicable1 country
- Safety and Potential Effect of Innovative Treatment by Adjuvant Injection of Stromal Vascular Fraction From Autologous Adipose Tissue of URethral Stenosis With Endoscopic UrethrotomyRecruitingNCT05857371Phase 21 country
- The Impact of Age and Sex on Anticipated and Experienced Pain in First-Time Outpatient Flexible CystoscopyNot yet recruitingNCT073756411 country
- Risk of Recurrent Urethral Stricture After Treatment With Paclitaxel-Coated Dilatation Balloon (Optilume) Compared With Non-coated Dilatation BalloonRecruitingNCT06795074Phase 41 country
- The Effects of Holmium Laser Enucleation and Thulium Laser Enucleation on Continence, Urethral Stricture, and Sexual Function in Benign Prostatic HyperplasiaNot yet recruitingNCT073347301 country
- Joshi's Step With Buccal Mucosal Graft Urethroplasty in Nearly Obliterated Bulbar Urethral StrictureRecruitingNCT07088198Not applicable1 country
- Penile Skin Versus Buccal Mucosal Graft in Augmentation Urethroplasty for Long Anterior Urethral StrictureRecruitingNCT07074717Not applicable1 country
- Treatment of Bulbar Urethral Strictures With Optilume Drug-Coated Balloons in an Untreated PopulationNot yet recruitingNCT06827210Not applicable1 country
- Multi-stage Urethroplasty with Augmentation Using a Dorsal Graft Inlay Technique Comparing Graft Use in First or Second StageRecruitingNCT04965025Not applicable1 country
- Role of Paclitaxel in Stricture UrethraRecruitingNCT05678413Not applicable1 country
- Urethral Stricture DatabaseRecruitingNCT063620831 country
- Vessel-sparing Technique Versus Conventional Repair of PFUI: A Prospective Comparative StudyNot yet recruitingNCT062480471 country
- DoVe Trial: Dorsal Onlay Versus Ventral Onlay in Isolated Bulbar Urethral StricturesRecruitingNCT04551417Not applicable1 country
- Small Intestinal Submucosa Graft for Repair of Anterior Urethral StricturesEnrolling by invitationNCT06192654Not applicable1 country
- 9000 URETHRA STUDY: a Study About Urethroplasty for Urethral Stricture DiseaseRecruitingNCT040719251 country
- Anatomical and Functional Outcome of PSG Vs BMG for Urethral Substitution in Long Segment Anterior Urethral StricturesRecruitingNCT06056856Not applicable1 country
- Comparison Between Two Techniques Used in Treatment of Long Anterior Urethral StrictureNot yet recruitingNCT05918315Not applicable1 country
- The Accuracy of Pulsed Fluoroscopy Retrograde Urethrogram Vs the Traditional Retrograde Urethrogram In Diagnosing Urethral StrictureRecruitingNCT05519566Not applicable1 country
- Platelet Rich Plasma Versus Mitomycin C Injection Following Visual Internal Urethrotomy in Urethral StrictureCompletedNCT07883837Phase 31 country
- Outcomes of Double-face Augmentation UrethroplastyActive, not recruitingNCT07436819Not applicable1 country
- The Effect of Platelet Rich Plasma Injection on Post Internal Urethrotomy Stricture RecurrenceCompletedNCT07837167Phase 31 country
- Optilume PoST AppRoval Clinical Evaluation of Andrology ParaMetersActive, not recruitingNCT05383274Phase 41 country
- Peri-operative Oral Pain Control Following Buccal Graft UrethroplastyCompletedNCT05300685Phase 31 country
- Early vs Late Urinary Catheter Removal After Renal TransplantationActive, not recruitingNCT04815954Not applicable1 country
- LishitonglinUS-01 TrialActive, not recruitingNCT07769060Phase 21 country
- Factors Predicting Urethral Stricture Recurrence After Dorsal Onlay Augmented, Buccal Mucosal Graft UrethroplastyCompletedNCT043570801 country
- ROBUST III- Re-Establishing Flow Via Drug Coated Balloon For The Treatment Of Urethral Stricture DiseaseActive, not recruitingNCT03499964Not applicable2 countries
- Bioengineered Collagen Implant for Urethral Stricture RepairCompletedNCT05463991Not applicable1 country
- Holmium Laser Versus Cold Knife Treatment in Urethral StricturesCompletedNCT07505316Not applicable1 country
- Re-establishing Flow Via Drug Coated Balloon For The Treatment Of Urethral Stricture DiseaseCompletedNCT03270384Not applicable1 country
- Optilume Registry for Treatment of Stricture of the Anterior UrethraActive, not recruitingNCT054794225 countries
- Effectiveness of Intermittent Bladder Catheterization (IBC) in Reducing Recurrence of Urethral StrictureCompletedNCT06064968Not applicable1 country
- Mobile Health Application to Improve Patient Satisfaction After UrethroplastyWithdrawnNCT06384066Not applicable1 country
- Efficacy of Opioid-limiting Pain Management Protocol in Men Undergoing UrethroplastyCompletedNCT03859024Phase 41 country
- ROBUST I Pilot Study, Re-Establishing Flow Via Drug Coated Balloon For The Treatment Of Urethral Stricture DiseaseCompletedNCT03014726Early Phase 11 country
- Intralesional Injection of Mitomycin C Following Visual Internal Urethrotomy for Recurrent Urethral StrictureCompletedNCT06232005Phase 2/31 country
- VeSpAR: Comparing Vessel-Sparing Anastomotic Repair and Transecting Anastomotic Repair in Isolated Short Bulbar Strictures.CompletedNCT03572348Not applicable8 countries
- Laser Visual Internal Urethrotomy With Versus Without Paclitaxel InjectionCompletedNCT06123520Phase 31 country
- Clostridium Histolyticum Collagenase Injection for Urethral DiseaseCompletedNCT02948842Phase 21 country
- Effect of Caudal and Penile Block on Hypospadias Repair ComplicationsCompletedNCT02851290Not applicable1 country
- Treatment of Urethral Stricture With Urethral Drug BallStatus unknownNCT05812482Not applicable1 country
- Diagnosis of Urethral Stricture With Sono-urethrography vs Conventional Urethrography (SONO-URETHRA)WithdrawnNCT01790776Phase 31 country
- Post-Operative Imaging After Urethroplasty With Peri-catheter Retrograde Urethrography Or Trial of Voiding With Voiding Cysto-urethrographyCompletedNCT04307537Phase 21 country