An interventional study of Joshi's step in Joshi's Step, Buccal Mucosal Graft and Urethroplasty, sponsored by Tanta University. Recruiting at 1 site in Egypt. Open to male participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-07-28.
Sponsored by Tanta University · Not applicable, Interventional, and Treatment
This study aims to evaluate the functional and surgical outcome of Joshi's step with buccal graft urethroplasty for the management of nearly obliterated bulbar urethral stricture.
Urethroplasty is a rapidly evolving art that continually improves and reinvents itself. After a century of silence, during which the anastomotic repair was the only solution for approaching the strictured urethra, the 1990s can be considered the Renaissance period for reconstructive urology.
In 2022, Joshi and Kulkarni introduced a new step to the augmented urethroplasty, particularly in patients with extremely narrow strictures where a single augmentation was insufficient. They avoid any resection of the residual native urethral plate, marking the narrowest portion. Then, the edges of the mucosa are reapproximated with interrupted suturing in a proper non-resecting approach.
Tanta University is the lead sponsor of 963 studies on the registry; 304 are open to participants now.
Of its 16 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Patients will undergo dorsal onlay buccal mucosal graft urethroplasty with Joshi's step
Procedure: Joshi's step
Patients will undergo dorsal onlay buccal mucosal graft urethroplasty with Joshi's step
Success rate
Incidence of success rate will be recorded.
Time frame: 6 months postoperatively
Urine flow rate
Urine flow rate will be recorded.
Time frame: 6 months postoperatively
The urethral lumen
The urethral lumen by ascending urethrogram will be recorded.
Time frame: 6 months postoperatively
Plan to share: Yes — The data will be available upon a reasonable request from the corresponding author after the end of study for one year.
Supporting information: Study protocol
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