An observational study in Urethral Stricture, sponsored by Al-Azhar University. Completed at 1 site in Egypt. Open to male participants. Per ClinicalTrials.gov, last updated 2026-08-14.
Sponsored by Al-Azhar University · Observational
In this observational study, the investigators will evaluate potential risk factors associated with urethral stricture recurrence after augmentation anterior urethroplasty using dorsal onlay buccal mucosal Graft during the past 10 years. Patients' medical files will be reviewed for data relevant to demographics, clinical and operative characteristics. data will be analyzed using the appropriate statistical tests and the independent predictors of urethroplasty outcome will be identified.
In this series, the investigators will study different factors related to the stricture and to the patients to identify the independent predictors of urethral stricture recurrence after augmentation anterior urethroplasty using dorsal onlay buccal mucosal graft.
A retrospective review of medical records will be performed to identify patients who underwent augmented anastomotic anterior urethroplasty with dorsal onlay graft at Al-Azhar University Hospitals in Egypt since 2010. Patients will be included only if they were two or more years out of surgery. The data will be recorded without patients' identification.
Data to be collected are patient age, body mass index (BMI), smoking status, diabetes status, overall comorbidity, stricture etiology, prior endoscopic treatment and open urethroplasty, urethral stricture length and location, degree of urethral obliteration, urethral plate width, presence and degree of spongiofibrosis. estimated intraoperative blood loss, catheter size, overall operative time, hospital stay and early postoperative complications.
The diagnosis of urethral stricture recurrence is based on the radiological and endoscopic features of stricture recurrence. Time to recurrence will be calculated from the date of surgery till the date restricture diagnosis.
Univariate and multivariate regression analysis will be performed and factors predicting urethral stricture recurrence will be identified.
68 studies on the registry are indexed under Urethral Stricture; 23 are open to participants now.
This study's enrollment of 266 is above the median of 188 across 10 observational studies indexed under Urethral Stricture.
Browse Urethral Stricture studies →Al-Azhar University is the lead sponsor of 505 studies on the registry; 167 are open to participants now.
Of its 5 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
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patients who underwent augmented anterior urethroplasty with buccal mucosal graft at Al-Azhar University Hospital in the past 10 years
Exclusion Criteria:
Patients with urethral stricture recurrence
Procedure: Urethroplasty
Patients with normal, patent urethra
Procedure: Urethroplasty
Augmentation Anterior Urethroplasty Using Dorsal Onlay Buccal Mucosal Graft
urethral restricture rate
The presence of radiologic and endoscopic features of urethral stricture recurrence, as diagnosed by urethrography and cystoscopy during follow-up.
Time frame: At any time from date of surgery until the last follow-up visit (up to 10 years)
Time to urethral restricture.
will be calculated from the date of surgery until the date restricture diagnosis
Time frame: The time from urethroplasty surgery until the time of urethral restricure diagnosis (at any follow-up time point, up to 10 years), as recorded in patients medical files).
Plan to share: Undecided
This study is completed, as verified in Apr 2020. You cannot join it, but the record below documents what was studied.
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Al-Azhar University