An interventional study of Fascial Distortion Model and Sham treatment in Temporomandibular Disorders (TMD), Manual Therapy and Fascial Distortion, sponsored by Karabuk University. Recruiting at 1 site in Turkey (Türkiye). Open to participants aged 18 Years to 64 Years. Per ClinicalTrials.gov, last updated 2026-08-05.
Sponsored by Karabuk University · Not applicable, Interventional, and Treatment
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Among 150 studies in Temporomandibular Joint Disorders with a site in Turkey — 27 open to participants now, 28 under way, none of them phase 3. Temporomandibular Joint Disorders · Turkey.
Among the 150 studies in Temporomandibular Joint Disorders with a site in Turkey, this one is the 64th largest by planned enrollment of the 80 interventional ones that give a count, is one of 23 that started in 2024, is one of 76 with no phase, reaches primary completion later than 12 of the 27 other live ones, and was the 86th registered.
591 studies on the registry are indexed under Temporomandibular Joint Disorders; 149 are open to participants now.
Browse Temporomandibular Joint Disorders studies →27 of the 150 studies in Temporomandibular Joint Disorders with a site in Turkey are open now. Recruiting first, the newest first:
Mustafa Kemal University · Sites in Turkey
Ages 35–75 · Healthy volunteers
sevilay seda bas · Sites in Turkey
Ages 18–55
Yuzuncu Yil University · Sites in Turkey
Ages 18–65
Uşak University · Sites in Turkey
Ages 18–65
Recep Tayyip Erdogan University · Sites in Turkey
Ages 18+ · Healthy volunteers
A study can be open while its sites in Turkey have not opened yet or have stopped. Only those recruiting at a site in Turkey →
Of the 75 Temporomandibular Joint Disorders studies recruiting now, 26 (35%) set no upper age limit and 45 (60%) stop at 75 or younger; 7 take children under 18; 23 take healthy volunteers.
This study: 18 Years to 64 Years · all sexes · no healthy volunteers.
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150 studies; the count open now beside each. This study's row is marked.
First in 2011; this study’s year is marked. 23 started in 2024.
By drug class, each counting the studies that test any of its medicines:
This study's planned enrollment of 30 is below the median of 45 across 415 interventional studies indexed under Temporomandibular Joint Disorders.
Median enrollment 45 across the 80 interventional studies, 78 across the 70 observational. Of the 114 that completed or were terminated, 4 (4%) have results posted.
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None of the 150 has an industry lead sponsor. The 10 most frequent:
Karabuk University is the lead sponsor of 143 studies on the registry; 40 are open to participants now.
Karabuk University has 1 study filed under Temporomandibular Joint Disorders — fewer than ten, so there is no comparison to draw.
4 of the studies in Temporomandibular Joint Disorders with a site in Turkey that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07577687Yuzuncu Yil UniversityEffect of Emg-Biofeedback and Multimodal Exercise on Temporomandibular Joint Dysfunction | 2026-12-15 |
| NCT07850674Mustafa Kemal UniversitySpinal Mobility, Rigidity, and Kinesiophobia in PD and TMD | 2026-12-23 |
| NCT07576582Uşak UniversityPeloid Therapy in Temporomandibular Joint Dysfunction | 2027-01-01 |
| NCT07791173Zeynep Serra KalkanEvaluation of Temporomandibular Disorders During Pregnancy | 2027-03 |
Add all 4 to your calendar (.ics) → With an account.
Among the 150 studies in Temporomandibular Joint Disorders with a site in Turkey, from their registry updates:
This tab as a report to print or save as PDF → With an account.
The aim of the study was to investigate the effectiveness of Manual Therapy Based on the Fascial Distortion Model in individuals with temporomandibular disorders compared to sham control. Individuals diagnosed with temporomandibular disorder will be randomly assigned to groups as Group 1 (Manual Therapy Based on Fascial Distortion Model) and Group 2 (Sham Control). Head posture, cervical and temporomandibular joint range of motion, cervical muscle performance, pain intensity, pressure pain thresholds, temporomandibular disorder severity, disability, dysfunction, health-related quality of life, kinesiophobia, and central sensitization will be assessed.
Interventions are needed to address head posture, cervical and temporomandibular joint range of motion, cervical muscle performance, pain intensity, pressure pain thresholds, temporomandibular disorder severity, disability, dysfunction, health-related quality of life, kinesiophobia, and central sensitization in individuals with temporomandibular disorder (TMD). This study aims to examine the effectiveness of Manual Therapy Based on the Fascial Distortion Model in individuals with TMDs compared to sham control over a 4-week period. Individuals with TMD will be randomized into Group 1 (Fascial Distortion Model-based Manual Therapy) or Group 2 (Sham Control). Interventions will be conducted once a week in a clinical setting. Head posture will be measured by lateral photogrammetry, cervical range of motion will be measured by an inclinometer, temporomandibular range of motion will be measured by a vernier caliper, cervical muscle performance will be measured by Cervical Spine Functional Strength Test, and pressure pain threshold will be measured by an algometer. Pain intensity will be assessed using the Graded Chronic Pain Scale (Revised) and the Short-Form McGill Pain Questionnaire. TMD severity will be assessed using the Fonseca Anamnestic Index. Mandibular Function Impairment Questionnaire will be used to assess dysfunction. Disability will be evaluated using the Craniofacial Pain and Disability Inventory. Health-related quality of life will be assessed using Short Form-36. Kinesiophobia will be assessed with the Tampa Kinesiophobia Scale; central sensitization will be assessed with the Central Sensitisation Inventory.
All outcomes will be measured at baseline and end of the study, while pain intensity and pressure pain thresholds will also undergo intermediate assessments (2nd and 3rd week).
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Exclusion Criteria:
It will conducted for forty-five minutes once a week in a clinical setting for 4 weeks.
Procedure: Fascial Distortion Model
Sham application will conducted for forty-five minutes once a week in a clinical setting for 4 weeks.
Procedure: Sham treatment
The following techniques were used on the cranial and cervical areas during therapy: Trigger band technique, herniated trigger point technique, continuum technique, folding technique, cylinder technique, and tectonic technique.
Also known as: Typaldos Manual Therapy
The techniques in the therapy will be applied by imitating the techniques in the therapy for the fascial distortions determined according to the Manual Therapy Based on the Fascial Distortion Model.
Head posture
Lateral photogrammetry according to Eye-Tragus-Horizontal Angle, Pogonion-Tragus-C7 Angle, Tragus-C7-Horizontal Angle, Tragus-C7-Shoulder Angle, and Shoulder-C7-Horizontal Angle.
Time frame: From enrollment to the end of treatment at 4th week
Cervical range of motions
Inclinometric measurements based on flexion, extension, lateral flexions, and rotations.
Time frame: From enrollment to the end of treatment at 4th week
Temporomandibular range of motions
Digital vernier caliper measurements based on maximum pain-free mouth opening, maximum possible mouth opening, maximum possible assisted mouth opening, laterotrusions, and protrusion.
Time frame: From enrollment to the end of treatment at 4th week
Cervical muscle performance
The Functional Strength Testing of the Cervical Spine was used to evaluate the cervical muscle performance. This is a test that functionally evaluates cervical muscle strength. Results of this test are assessed as functional, functionally fair, functionally poor, and nonfunctional. Six-to-eight repetitions for the flexion test and 20-25 s holding time for the other tests indicate that the test result is functional. Three-to-five repetitions for the flexion test and 10-19 s holding time for the other tests indicate that the test result is functionally fair. One-to-two repetitions for the flexion test and 1-9 s holding time for the other tests indicate that the test result is functionally poor. Zero repetition for the flexion test and 0 s holding time for the other tests indicate that the test result is nonfunctional. Each test was terminated at onset of pain, and the relevant value was recorded.
Time frame: From enrollment to the end of treatment at 4th week
Pressure pain threshold
Algometer. Tempormandibular joint, masseter, temporalis anterior, suboccipital muscle, trapezius, lateral epicondyle for both side.
Time frame: From enrollment to the end of treatment at 1st week, 2nd week, 3rd week, and 4th week.
Pain intensity in the last week
Short-Form McGill Pain Questionnaire. Minimum and maximum values are 0 and 3 points, respectively. Higher scores mean a worse outcome.
Time frame: From enrollment to the end of treatment at 1st week, 2nd week, 3rd week, and 4th week.
Chronic pain intensity
Graded Chronic Pain Scale (Revised). Scoring: Grade 1=mild, Grade 2=bothersome, Grade 3=high impact chronic pain. Higher scores mean a worse outcome.
Time frame: From enrollment to the end of treatment at 1st week, 2nd week, 3rd week, and 4th week.
Temporomandibular disorders severity
Fonseca Anamnestic Index. Minimum and maximum values are 0 and 10 points, respectively. Higher scores mean a worse outcome.
Time frame: From enrollment to the end of treatment at 4th week
Dysfunction
Mandibular Function Impairment Questionnaire. Minimum and maximum values are 0 and 4 points, respectively. Higher scores mean a worse outcome.
Time frame: From enrollment to the end of treatment at 4th week
Disability
Craniofacial Pain and Disability Inventory. Minimum and maximum values are 0 and 3 points, respectively. Higher scores mean a worse outcome.
Time frame: From enrollment to the end of treatment at 4th week
Health-related quality of life
Short Form-36. Its subdomains are physical functioning, role physical, bodily pain, general health, vitality, social functioning, role emotional, and mental health.
Time frame: From enrollment to the end of treatment at 4th week
Kinesiophobia
Tampa Kinesiophobia Scale for Temporomandibular Disorders. Minimum and maximum values are 1 and 4 points, respectively. Higher scores mean a worse outcome.
Time frame: From enrollment to the end of treatment at 4th week
Central sensitization
Central Sensitisation Inventory. Minimum and maximum values are 0 and 4 points, respectively. Higher scores mean a worse outcome.
Time frame: From enrollment to the end of treatment at 4th week
Present pain intensity
Visual Analog Scale. Minimum and maximum values are 0 and 10 cm, respectively. Higher scores mean a worse outcome.
Time frame: From enrollment to the end of treatment at 1st week, 2nd week, 3rd week, and 4th week.
Present pain intensity (ordinal)
Present pain intensity scale of McGill Pain Questionnaire. Minimum and maximum values are 0 and 5 points, respectively. Higher scores mean a worse outcome.
Time frame: From enrollment to the end of treatment at 1st week, 2nd week, 3rd week, and 4th week.
Pain intensity in the last week (ordinal)
Numeric Pain Rating Scale. Minimum and maximum values are 0 and 10 points, respectively. Higher scores mean a worse outcome.
Time frame: From enrollment to the end of treatment at 1st week, 2nd week, 3rd week, and 4th week.
Plan to share: No
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Ran from Oct 2024 to primary completion in Dec 2024, 2 months.
Of 242 non-industry interventional studies with no phase under Temporomandibular Joint Disorders, half reached primary completion within 11 months of starting (the median), counting those still running; a quarter within 5 and three quarters within 21. This study's 2 months is below that.
Counting every sponsor, half of 246 studies reached it within 10 months; a quarter within 5 and three quarters within 21.
How these figures are worked out, and which studies are left out of them.
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Temporomandibular Joint Disorders →